
#401: Personalization Is EVERYTHING: The New Science of Weight Health, GLP-1s, and Building Lasting Longevity With Ashley Koff
2026/1/06 | 1h 38 mins.
Today, I'm joined by the insightful Ashley Koff, renowned registered dietitian and fierce advocate for personalized, realistic nutrition that actually works in the real world. In this episode, Ashley Koff opens up about her personal and professional journey—from her early days in big brand marketing (think sugared cereals and infobesity) to her pivotal "aha" moments that led her to champion true weight health, not just weight loss. Episode Timestamps: Welcome and introduction to the Longevity Podcast ... 00:00:00 Personal experiences shaping nutrition philosophy ... 00:05:59 Influence of marketing on nutrition decisions ... 00:09:01 Big revelations: digestion, GLP-1, and health ... 00:16:43 The power of personalization in nutrition ... 00:19:59 The "Mr. Pizza Pop" case and behavioral change ... 00:23:03 Digestion as the foundation before diet quality ... 00:27:05 Dangers of generic "healthy diet" advice ... 00:36:01 GLP-1 medications: promise, risks, and prerequisites ... 00:40:10 Who truly needs GLP-1 versus lifestyle change alone ... 00:43:09 Muscle, bone, and shifting focus to building health ... 00:51:30 Nutrient intake, fiber, and supplement personalization ... 00:55:11 Digestive enzymes and optimizing digestion ... 01:03:10 Food noise, satiety, and psychological freedom ... 01:07:29 Ongoing assessment: tracking weight, fat, muscle ... 01:15:19 Weaning off GLP-1 and the importance of professional support ... 01:18:32 Our Amazing Sponsors: Primeadine by Oxford Healthspan: Primeadine supports autophagy — your cells' natural renewal and cleanup process — using food-derived spermidine, no fasting required. If you want to support resilience from the inside out, head to https://www.oxfordhealthspan.com/BIONAT15 and use code BIONAT15 at checkout (one-time purchases only). Magnesium Breakthrough by BiOptimizers: Better sleep isn't about willpower — it's about absorption. Magnesium Breakthrough uses seven real forms of magnesium that help you rest deeper and recover faster. Get up to 35% off at bioptimizers.com/bionat with code BIONAT. Just Thrive Gut Essentials Bundle: pairs a probiotic proven to arrive 100% alive with digestive bitters that support digestion and curb cravings, so you actually feel the difference fast. Save 20% on your first Gut Essentials Bundle at justthrivehealth.com/NAT20 with code NAT20 — 100% money-back guarantee. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

#400: Why Chasing Muscle for Longevity Might Backfire: The Real Keys to Aging Well With Joel Greene.
2026/1/02 | 1h 33 mins.
Today, I'm excited to bring back the always thought-provoking Joel Greene, author of "The Immunity Code" and "The Way," for a fresh conversation on why true longevity is about so much more than how much muscle you have or the latest diet trend you're following. Joel Greene opens up about the hard lessons he's learned from decades of self-experimentation and reveals why chasing that ideal gym physique might actually backfire as you age. Episode Timestamps: Welcome & episode introduction ... 00:00:00 The evolving nature of health and homeostasis ... 00:08:29 Beware rigid diet tribes—find nutritional flexibility ... 00:21:41 Biomarkers people miss: fasting insulin and acyl carnitines ... 00:23:11 Chronic ketosis, ATP, and metabolic slowdowns ... 00:25:16 Myth-busting muscle and the limits of bodybuilding for aging ... 00:27:17 Functional movement, flexibility, and big toe strength ... 00:34:29 Simple foundation: daily jumps or hops ... 00:47:41 Sensible protocols for muscle gain after 50 ... 01:00:07 Balance in diet as the true key to insulin sensitivity ... 01:08:06 Rules of thumb: meal timing for insulin ... 01:15:56 Stillness, faith, and feeding your spirit ... 01:21:56 Most abused supplement: Antioxidants ... 01:27:54 Body fat percentage as top longevity marker ... 01:29:12 Our Amazing Sponsors: Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial. Blue Peptide Spray from Young Goose - Brings the message back loud and clear. With NAD+ APEX™️ to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Mitopure® Longevity Gummies are the only clinically proven Urolithin A gummies supporting mitochondrial health — one of the key hallmarks of aging. Get 35% off a one-month subscription at Timeline.com/Nat2026 *Special deal through January 2026. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

#399: Longevity Rewired: Hormones, Sunlight & The Weight Loss LIE | Reversing Aging in 2025 With Nat Niddam
2025/12/26 | 38 mins.
Today, I'm joined by a lineup of trailblazers in the science of longevity: Ben Azadi, Dr. Teo Soleymani, Dr. Carrie Jones, Ian White, Dr. Robert Lufkin, and Dr. Jenn Simmons . Together we dig into some of the most persistent myths and cutting-edge research shaping how we age—including why "eat less, move more" misses the mark, what really causes skin cancers, breast cancer screening risks, and the often-overlooked ripple effects of perimenopause. Links to full episodes: #333: Keto Myths, Carb Days, and Why Calories Don't Count | Ben Azadi on Breaking the Weight Loss Cycle Episode 338: How the Sun ACTUALLY Impacts Skin Aging and Cancer Risk: Skin Cancer Controversies, Sun Safety Secrets, and Anti-Aging Breakthroughs With Teo Soleymani, MD Episode 376: Survival Tips for Perimenopause, NEW At-Home Hormone Testing & Bioidentical Myths With Dr. Carrie Jones Episode 350: Nature's Longevity CODE Revealed: Exosomes, Plasma HACKS & the Real Science of Aging | With Dr. Ian White Episode 318: Lies He Taught In Medical School: The METABOLIC Secret To Reversing Chronic Disease with Dr. Robert Lufkin Episode 300: Breast Cancer Overdiagnosis, Mammogram Myths, The REAL Risks For Women And Bold NEW Alternatives With Dr. Jenn Simmons Episode Timestamps: Welcome & podcast overview ... 00:00:00 Longevity habits handout & sponsor plug ... 00:00:48 Clean protein choices & contamination risks ... 00:01:25 Calorie focus vs. hormones in weight loss ... 00:02:42 Why calories in/calories out fails ... 00:03:27 Cellular inflammation & gut microbiome in weight ... 00:04:43 Healthy, flexible metabolism over fast metabolism ... 00:07:51 Sun exposure, genetics & skin cancer ... 00:08:02 Sunscreen myths & ingredient safety ... 00:11:47 Perimenopause symptoms beyond hot flashes ... 00:12:27 Hormone replenishment: lifestyle + medical strategies ... 00:15:35 Breaking menopause myths & self-education ... 00:19:05 Blood factors & parabiosis in aging ... 00:21:37 Plasma exchange — practical and scientific updates ... 00:26:01 Western medicine vs. chronic disease reality ... 00:28:07 Breast cancer screening & over-treatment concerns ... 00:33:16 Hormone therapy after menopause—timing & benefits ... 00:37:07 Our Amazing Sponsors: PW1 protein powder is third-party tested for more than 200 contaminants, and Puori was the only brand that earned the Clean Label Project Transparency Certificate. That level of disclosure is rare. And refreshing. If you want protein that supports your goals — without the guesswork — go to Puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site. Manukora - Now in NEW Glass Jars - This isn't regular honey. Manukora's bees collect nectar from the Manuka tea tree, which packs 3x more antioxidants and prebiotics than normal honey. Plus it naturally contains MGO, that rare antibacterial compound. Head to MANUKORA.com/NAT to save up to 31% plus get $25 worth of free gifts with the Starter Kit. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

#398: The Dopamine Biohack | Brain Chemistry, Motivation & Testosterone Secrets Revealed With Lucas Aoun
2025/12/23 | 1h 24 mins.
Today, I'm joined by Lucas Aoun, from Australia, supplement formulator, and self-described human guinea pig. Lucas and I dive into his personal journey from working behind the counter at his father's pharmacy, to experimenting with early nootropic formulas, and ultimately becoming a sought-after educator in the world of biohacking. Episode Timestamps: Podcast introduction and guest welcome ... 00:00:00 Lucas Aoun's journey into biohacking ... 00:04:13 Innovative supplement formulation and teacrine ... 00:10:00 Dopamine's role in motivation and productivity ... 00:32:09 Bioindividual supplement responses and AI in health ... 00:17:00 Alcohol alternatives and social nootropics ... 00:39:52 Optimizing exercise timing and performance ... 00:48:49 Testosterone, thyroid, and men's health fundamentals ... 00:53:01 Diet diversity: carnivore, vegan, and healthy fats ... 00:59:19 Catwaba Pure: origins, benefits, and uses ... 01:13:12 Our Amazing Sponsors: Nootropept by LVLUP - an advanced cognitive enhancement formula that combines fast-acting neuropeptides, cholinergic support, and mitochondrial-boosting compounds to sharpen mental clarity, memory, and long-term brain performance. Visit https://lvluphealth.com/ and use code NAT at checkout for 20% off. PW1 protein powder is third-party tested for more than 200 contaminants, and Puori was the only brand that earned the Clean Label Project Transparency Certificate. That level of disclosure is rare. And refreshing. If you want protein that supports your goals — without the guesswork — go to Puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site. NEW Timeline Gummies: Urolithin A supports muscle strength and cellular energy. It's about improving how your body functions at the source. Mitopure is the only clinically proven Urolithin A, giving you six times more than you'd get from a glass of pomegranate juice. Visit Timeline.com/nat20 and use code nat20 for 20% off your purchase. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group

#397: STRESS: The Silent Accelerator of Aging (10 Free Hacks Rewiring Your Longevity) | Calm Amid Chaos With Nat Niddam
2025/12/19 | 39 mins.
Today, it's just me, and we're doing things a little differently on the Longevity Podcast. With the intensity of the holiday season winding down, I wanted to take a step back from the usual deep-dives and high-tech hacks to focus on something fundamental—free, practical strategies to help you manage stress. Chronic stress is sneaky in how it accelerates aging, impacts your telomeres, and undoes even the most powerful interventions, but thankfully, there are simple ways we can start to turn things around. Episode Timestamps: Welcome and episode introduction ... 00:00:00 Immune support with bioregulators ... 00:00:40 Why focus on free stress management tools ... 00:01:54 How chronic stress accelerates aging ... 00:04:32 Stress undermining longevity interventions ... 00:05:13 The importance of nervous system balance ... 00:06:50 Recognizing hidden stress and using HRV ... 00:07:45 When to seek further medical help ... 00:09:46 Recap: chronic stress shortens your healthspan ... 00:10:21 10 free strategies to manage stress ... 00:12:25 Connection and volunteering ... 00:13:15 Break the doom scrolling habit ... 00:17:37 Benefits of time in nature ... 00:20:02 Exercise for resilience ... 00:22:41 Breath work and vagus nerve support ... 00:25:33 Practicing gratitude daily ... 00:31:33 The power of sleep ... 00:34:30 Taking time for yourself ... 00:35:19 Our Amazing Sponsors: Nature's Marvels by Profound Helath - The Thymus Bioregulator helps keep immune response balanced and small human studies in older adults link it with healthier immune markers and fewer seasonal respiratory issues. The Pineal Bioregulator supports your natural melatonin/circadian rhythm—key when schedules and daylight change—so you get the kind of sleep that underpins immune resilience. Head to profound-health.com and use code NAT15 for 15% off your first order. Fatty15: C15 is 3x more effective than omega-3 and totally vegan. You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/NATNIDDAM and using code NATNIDDAM at checkout. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group



LONGEVITY with Nathalie Niddam