LONGEVITY with Nathalie Niddam

Today, I've got a conversation that goes deep into the cutting edge of regenerative skin health with two exceptional guests: Debbi Barber, founder and muse of Vitali Skincare, and Dr. Jordan Plews, a biochemical engineer and stem cell researcher. We discuss the science and practical realities of exosomes, stem cells, and copper peptides—breaking down not just what makes skin look younger, but what truly keeps it biologically healthier and more resilient as we age.

Visit https://www.vitaliskincare.com/?ref=Nat20 and use code Nat20
 
Episode Timestamps:
Welcome and podcast purpose ... 00:00:00
Shift from beauty to science and health ... 00:09:23
GHK-Cu's role in longevity and skin repair ... 00:10:15
Dr. Plews on regenerative medicine and stem cells ... 00:11:14
From peptides to exosomes: product evolution ... 00:13:35
Stem cell exhaustion and need for exosome signaling ... 00:14:07
Copper peptides vs. exosomes: complementary actions ... 00:18:00
Why source and age of exosomes matter ... 00:25:20
Quality, safety, and labeling in exosome products ... 00:35:01
How exosomes and peptides benefit skin deeper layers ... 00:44:35
Visible results: barrier, redness, scars, texture ... 00:58:05
What to expect: younger vs. older skin ... 01:00:01
Proof and stories: customer transformations ... 01:01:59
More isn't better: exosome dosing myth ... 01:07:03
Supporting ingredients: vitamin C, glutathione, SOD2 ... 01:11:31
Skin as a window into systemic aging ... 01:19:08
The future: personalized, organ-targeted exosome therapies ... 01:24:02
 
Our Amazing Sponsors:
Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order.
 
Manukora Honey - rich, creamy Manuka honey packed with powerful bioactives, all in just one heaped teaspoon a day. Go to MANUKORA.com/NAT to save up to 31% plus $25 in free gifts with the Starter Kit.

PW1 by Puori — A clean, high-quality whey protein that's third-party tested for over 200 contaminants and smooth enough to feel like a treat while supporting muscle, metabolism, and bone strength. Go to puori.com/NAT and use code NAT for 32% off your first subscription or 20% off anything on the site.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by Dr. Stephen Hussey—a clinician, author of Understanding The Heart, and a powerful force in rethinking everything we thought we knew about heart disease. Dr. Hussey's own journey began with type 1 diabetes as a child, and despite living a healthy, active lifestyle, he experienced a widowmaker heart attack at just 34 years old. In our conversation, he opens up about what it was like to face this crisis with "perfect" lab numbers, how it challenged his entire perspective, and ultimately led him to a radical new understanding of heart health and longevity.
 
Episode Timestamps:
Podcast introduction and heart disease focus ... 00:00:00
Dr. Stephen Hussey's health story and diabetes management ... 00:04:16
Heart attack, hospital experience, and challenging cholesterol dogma ... 00:15:04
How Dr. Hussey reversed arterial plaque ... 00:21:47
Rethinking heart function: vortex vs. pump ... 00:24:17
Structured water, hydration, and blood flow ... 00:36:39
Sunlight, grounding, and circadian rhythm for heart health ... 00:46:13
Impact of EMFs on blood and cellular energy ... 01:01:03
Actionable strategies to future-proof your heart ... 01:08:17
Trauma and emotional health in longevity ... 01:10:14
Evaluating your healthcare team holistically ... 01:12:28
Dr. Hussey's philosophy on nature and letting go ... 01:21:05
Closing thoughts and how to find Dr. Hussey ... 01:28:14
 
Our Amazing Sponsors:
Cozy Earth by Cozy Earth – Thoughtfully designed bedding and bath essentials that turn your home into a calm, elevated retreat and actually hold up wash after wash. Give your space a reset at cozyearth.com with code LONGEVITY for up to 20% off, and don't forget to mention this podcast in the post-purchase survey.
 
O₃RACLE™ by Wizard Sciences — A daily ozonated oil capsule designed to support immune balance, cellular communication, and antioxidant production without clinics, machines, or complicated routines; learn more at wizardsciences.com and use code NAT15 for 15% off.
 
Vitali - combines pharmaceutical-grade copper peptides with zero-age exosomes to support clearer cellular signaling and long-term skin resilience, working with your biology instead of forcing change. Visit VitaliSkincare.com and use code NAT20 for 20% off.
 
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Dr. Bill Lawrence Episode

Today, I'm joined by the wonderful Dr. Shivani Gupta, a true force in bridging ancient Ayurvedic wisdom with cutting-edge modern research on inflammation and healthy aging. She recently authored The Inflammation Code. Dr. Shivani opens up about her deeply personal motivation—from witnessing her grandfather's preventable health decline to spending years in both traditional and scientific studies, ultimately earning a PhD focused on turmeric and chronic inflammation.
For Dr. Shivani's Turmeric and sleep gummies visit https://fusionaryformulas.com/?sca_ref=9671225.dtSyos3QQx1c and use code NAT15 for 15% off.
 
Episode Timestamps:
Welcome & Introduction to Longevity Podcast ... 00:00:00
Autophagy & Spermidine Supplementation ... 00:02:41
Personal Connection & Product Experience ... 00:03:46
Health Declines in Modern Indian Culture ... 00:07:47
Reversing Disease: Ayurveda & Biohacking ... 00:11:11
Discovering Ayurveda & Turmeric's Power ... 00:15:12
Turmeric vs. NSAIDs: Scientific Support ... 00:19:52
PPIs, Gut Health, and Curcumin ... 00:21:26
Inflammation as the Root of Chronic Disease ... 00:23:24
Sleep Rituals & Circadian Timing ... 00:28:59
Elemental Design / Doshas Explained ... 00:32:13
Aligning Lifestyle with Dosha for Health ... 00:42:46
Mental Inflammation: Stress & Burnout ... 00:46:00
Turmeric Science, Uses & Myths ... 00:54:20
Personalized Spice Use & Dosha Guidance ... 01:03:48
Top Spices for Longevity ... 01:07:44
Cautions: Medications & Turmeric ... 01:10:03
The Future of Inflammation in Medicine ... 01:11:11
Rapid-Fire Longevity Habits ... 01:15:03
 
Our Amazing Sponsors:
Complete Liver Complex by LVLUP Health - supports your liver's natural detox pathways so your body can reset without suffering. Go  to lvluphealth.com and use code NAT for 20% off.
 
Primeadine by Oxford Healthspan — A food-derived spermidine supplement that supports autophagy and cellular renewal without fasting, made from Japanese wheat germ with clean, rigorously tested ingredients (including a gluten-free option); visit oxfordhealthspan.com/BIONAT20 and use code BIONAT20 at checkout.
 
Gut Essentials Bundle by Just Thrive — A powerful duo of a clinically proven probiotic and digestive bitters to reduce bloat, boost energy, curb cravings, and help you feel your best fast, backed by a 100% money-back guarantee — Take the Feel Better Challenge and save 20% at JustThriveHealth.com/NAT20 with promo code NAT20.
 
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Today, I'm joined by the inspiring Dr. Jeffrey Gladden—a trailblazer in longevity medicine who once spent decades as an interventional cardiologist, only to challenge everything he knew after his own health hit a wall. Dr. Gladden opens up about the moment he refused to accept "normal for your age" as a diagnosis, launching himself into the world of functional and age-management medicine to reclaim his vitality and help others do the same.
 
Episode Timestamps:
Welcome and episode introduction ... 00:00:00
Health crisis and discovering personal optimization ... 00:07:05
From "sick care" to health optimization ... 00:10:46
Vision for personalized, youthful longevity ... 00:12:17
Personalized medicine: why one size doesn't fit all ... 00:16:00
Linear versus exponential aging; fixing a flawed approach ... 00:18:02
Five circles of exponential health: key longevity domains ... 00:19:23
Curiosity, growth mindset, and quantum thinking in longevity ... 00:22:22
Why individualization is crucial for diet and interventions ... 00:28:52
Insulin resistance: the hidden driver of aging ... 00:33:41
Environmental and internal (psychospiritual) factors in health ... 00:38:40
Healing through meditation, stress management, and flow ... 00:41:15
Robustness, resilience, and anti-fragility as longevity superpowers ... 00:57:09
Safe, personalized hormone therapy and the importance of tracking ... 01:03:33
Integrating mindset, purpose, and psycho-spiritual work ... 01:08:50
Peptides and advanced therapies: preparing for optimal results ... 01:09:56
Common test misconceptions in longevity medicine ... 01:12:56
Debunking the myth of single biological age ... 01:16:38
Resources, connect with Dr. Gladden, and closing ... 01:18:09
 
Our Amazing Sponsors:
Youth Daily by Young Goose — An all-in-one moisturizer powered by NAD+ nano precursors to boost elasticity, smooth wrinkles, and keep your skin looking fresh, dewy, and full of life; grab yours at younggoose.com and use code Nat10 for first orders or 5NAT for returning customers.
 
Quantum Upgrade - Supports nervous system balance without wearables or apps—just effortless, 24/7 quantum energy streaming. With 21+ studies showing measurable improvements in stress and cellular function, it's easy to try for yourself. Visit quantumupgrade.io/NAT and use code NAT10 to start the free trial.
 
Mitopure®️ Longevity Gummies by Timeline — Clinically backed Urolithin A supports mitochondrial health to boost energy, recovery, and healthy aging, all in an easy daily gummy instead of another pill; go to timeline.com/nat20 for 20% off Mitopure®️ Gummies.
 
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Today, I'm sitting down with Dr. Gus Vickery, a good friend and one of my favorite collaborators when it comes to cutting-edge insights in personalized health and longevity. In this episode, I put myself under the microscope as we walk through my own metabolomics testing after a period of heavy travel, stress, and—yes—a break from my usual supplement routine. If you've ever wondered whether skipping your foundational health habits "just for a little while" really matters, you're about to find out.

If you are a clinician and would like to offer the Aristotle test to your patients please use this link to learn more about the Theriome test: therio.me/niddam 
If you are a patient and would like to run the Theriome Aristotle test and get a full interpretation and protocol based on your results from Dr Vickery & his team please use this link: https://authentichealth.com/precision-health-evaluation/
 
Episode Timestamps:
Introduction to Longevity Podcast and episode overview ... 00:00:00
Metabolomics and interpreting health data – practitioner guidance needed ... 00:05:05
Combining metabolomics, gut, and blood data for whole-system insights ... 00:06:02
Nutrient depletion and oxidative stress: critical findings ... 00:18:57
Supplementation essentials for aging well ... 00:27:05
Metabolomics comparison by age group and optimization goals ... 00:29:03
Stacking interventions: why less is more with diagnostics ... 00:31:05
Functional health markers and the value of context ... 00:34:47
Sympathetic dominance, mindset, and impact on longevity ... 00:35:26
Restoring nervous system balance – inner work and tech tools ... 00:42:38
Toxins, heavy metals, and practical detox strategies ... 00:49:11
Clean environment, resiliency, and realistic lifestyle shifts ... 00:55:29
Key nutrient deficiencies revealed by metabolomics ... 01:09:15
Genetic and metabolomic tests: what's actionable? ... 01:15:07
Hope for the future: human resilience and expanding technology ... 01:22:24
Weekly actionable: walk outside for mitochondria and stress relief ... 01:26:55
 
Our Amazing Sponsors:
Cozy Earth – Thoughtfully designed bedding and bath essentials that turn your home into a calm, elevated retreat and actually hold up wash after wash. Give your space a reset at cozyearth.com with code LONGEVITY for up to 20% off, and don't forget to mention this podcast in the post-purchase survey.
 
Nature's Marvels Bioregulators - provide gentle, organ-specific support — and the Liver Bioregulator is a favorite this season for supporting detox pathways and metabolic flow. Head to profound-health.com and use code NAT15 for 15% off your first order.

Blue Peptide Spray from Young Goose brings the message back loud and clear. With NAD+ APEX to refuel energy, methylene blue to recharge your mitochondria, and GHK-Cu to tell your skin, "Hey, start making that collagen again!" It's longevity science, not cosmetic hype. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.
 
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