Boundless Life

Full show notes: bengreenfieldlife.com/pharma
In this special repeat episode, Dr. Sandra Kaufmann breaks down which pharmaceuticals mimic the effects of things you already do for your health: what replaces a sauna session, what replaces a fast, what replaces a cold plunge (use code BENFORGE for $500 off select products), and what she takes with meals to blunt the damage from glucose spikes. I'm re-airing it now because of a new Nature paper finding that lithium is a naturally occurring brain nutrient, and that losing it may be one of the earliest steps toward Alzheimer's, at a dose in exactly the range Dr. Kaufmann described on this show years earlier.
You'll hear why she prefers pioglitazone over metformin for autophagy, how a Japanese gastritis drug connects to Alzheimer's, and how she worked her way up on an emergency blood pressure medication, starting at a dose that nearly knocked her off her feet and climbing to 100mg with no effect at all. The centerpiece is lithium (code BGL10 for 10% off): why the doses hidden inside popular nootropics are a fraction of what she considers useful, and everything it appears to do beyond mood, from controlling a pore in your mitochondria to building bone and growing new neurons. You'll also get her honest take on gene therapy versus pharmaceuticals, why peptides underperform in an older cell, and which molecule finally knocked astaxanthin off the top of her ranking system.
Episode Sponsors:
Xtendlife Prosta Support Advanced: A comprehensive daily prostate support formula combining saw palmetto, beta-sitosterol, vitamins, minerals, and botanicals to support prostate health, urinary function, and healthy aging. Visit Xtendlife.com/BensChoice and use code GREENFIELD for 15% off your order today.
BON CHARGE: BON CHARGE is a holistic wellness brand whose products help you sleep better, perform better, recover faster, balance hormones, and reduce inflammation. Go to boncharge.com/GREENFIELD and use coupon code GREENFIELD to save 15%.
Tecton Ketones: Tecton Ketones deliver bioidentical D-beta-hydroxybutyrate (BHB), the same ketone molecule your body produces during ketosis, for clean cognitive support and stable energy with no conversion step. Visit tectonketones.com/ben and use code BEN for 16% off your first order.
Dr. Murray Natural Products – ThymoQuin®: ThymoQuin® is a clinically researched black seed oil formulated to support healthy cortisol levels, improve resilience to everyday stress, and promote overall well-being. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products.
Hiya: Give your kids the full-body nourishment they need to grow into healthy adults. I've secured a special deal with Hiya on their best-selling children's vitamin, 50% off your first order. Go to hiyahealth.com/BEN (it is not available on their regular website).
See omnystudio.com/listener for privacy information.

Full show notes: bengreenfieldlife.com/505
In this solosode, you'll get the latest on microplastics, spinal disc health, and what a heart scan sees that a cholesterol panel misses. A new seven-day trial pitted five plastic-avoidance strategies against each other, and the results tell you exactly where to spend your effort if you can't overhaul everything at once. You'll hear which plastic sources matter most and what I now take before bed with BrocElite® (use code BEN for 25% off your first month) to help clear microplastics from tissue. Then I get personal about my back. I'll walk you through my full-body MRI results, which show significant degeneration from L1 to S1, and explain why I still have almost zero back pain, from Dr. Stuart McGill's Big 3 to inversion hanging, the couch stretch, the founder stretch from Foundation Training, and my WALKOLUTION® treadmill desk ($100 off, enter your email for a unique code). You'll also learn why running was the only activity linked to healthier spinal discs in a study of more than 4,000 people, and why none of the sports people assume are hard on your back showed harm. Finally, you'll hear what a coronary CT angiography measures that your cholesterol panel cannot, why a 6,061-person study found plaque volume beats any standard risk calculator, what my own scan revealed, and the surprisingly simple thing that appears highly protective even when your plaque is already elevated.
Episode Sponsors:
ULTRA: ULTRA is a clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, with no jitters, crashes, or sleep disruption. Visit takeultra.com and use code BENGREENFIELD for 15% off.
Forkful: Forkful delivers chef-cooked, fresh, ready-to-eat meals made with premium ingredients like grass-fed bison and wild-caught salmon, with zero seed oils and no prep or cleanup, ready in under 3 minutes. Visit ForkfulMeals.com and use code BEN50 for 50% off your first order.
Quantum Upgrade: Recent research revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20 to 25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io.
Supzential: More Than a Toothpaste: Created by biological dentist Dr. Dome, it combines highly bioavailable hydroxyapatite, a patented probiotic, xylitol, and lactoferrin to support enamel remineralization and a healthy oral microbiome, with no fluoride, SLS, or titanium dioxide. Visit Supzential.com and use code BEN20 for 20% off your order today.
Active Skin Repair: Active Skin Repair uses hypochlorous acid, a molecule your body naturally produces, to support skin repair and defense without harsh chemicals, from post-workout irritation to everyday skin support. Go to ActiveSkinRepair.com and use code BEN for 20% off, or find it on Amazon and at your local CVS.
See omnystudio.com/listener for privacy information.

Full show notes: https://bengreenfieldlife.com/holyhealth
In this episode with Justin Roethlingshoefer, you'll hear from a former NHL performance coach turned health entrepreneur whose new book, Holy Health, is the one I chose for my father-son book club this month. This is not another eat-honey-and-drink-milk Bible health book. Justin is a genuine biohacker who works with pro athletes worldwide, and he has woven deep spiritual and physiological science into the same framework.
You'll learn why the modern obsession with optimization can quietly become idolatry, how the drive to control your metrics keeps your nervous system stuck in fight-or-flight and lowers your HRV, and the five "hearts" that trap high performers in striving. You'll also get the practical side: his full morning and evening rhythms, why he starts his day at 6 p.m. rather than at sunrise, the breathwork he does midday in the grass, his exact zone two and zone five weekly targets, and how he folds three and a half hours of zone two into family walks with a weighted vest. It's a conversation about doing less frantic optimizing and more intentional stewardship, and it may reframe how you think about every biohack you own.
Episode Sponsors:
Tiny Health: An at-home microbiome test that uses metagenomic sequencing to analyze your full gut ecosystem and give personalized, evidence-based diet, lifestyle, and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN.
Timeline: Give your cells new life with Mitopure, which unlocks a precise dose of the rare Urolithin A molecule to promote healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN.
JOYMODE: Spice things up in the bedroom and boost your sexual performance naturally, without prescription drugs. Visit tryjoymode.com/BEN or enter BEN at checkout for 20% off your first order.
Supzential: More Than a Toothpaste: Created by biological dentist Dr. Dome, it combines bioavailable hydroxyapatite, a patented probiotic, xylitol, and lactoferrin to support enamel remineralization and a healthy oral microbiome, with no fluoride, SLS, or titanium dioxide. Visit Supzential.com and use code BEN20 for 20% off.
BIOptimizers Magnesium Breakthrough: Seven essential forms of magnesium in one full-spectrum serving to help you relax, unwind, and sleep deeply so you wake up refreshed. Go to bioptimizers.com/ben and use code ben15 for 15% off any order.
See omnystudio.com/listener for privacy information.

Full show notes: https://bengreenfieldlife.com/504
In this solosode, you'll get the latest research on three questions I keep getting asked. First, seed oils: a brand-new randomized controlled trial put 52 adults on either a low or a typical Western intake of linoleic acid for 12 weeks, and the results are important less for what they found than for what they didn't. You'll hear why arachidonic acid didn't move, why EPA dropped instead, what that does to your inflammatory balance, which seed oils I still think are worth avoiding, and the one dietary adjustment that matters most if seed oils are part of your diet.
You'll also learn the surprisingly small amount of strength training that delivers the biggest longevity payoff, according to a 30-year study of more than 147,000 people, plus why pairing it with cardio is the single best exercise combination for blood pressure. I break down concurrent training, the interference effect between AMPK and mTOR, and when combining strength and cardio in one session helps you versus when it holds you back. Finally, I answer a listener question on peptides with six practical rules for stacking them safely, including which ones should never share a syringe, which ones cancel each other out at the receptor, and an honest look at how thin the human evidence really is behind the popular Wolverine stack.
Episode Sponsors:
Young Goose: Cutting-edge skincare that supports your skin's cellular health. Visit younggoose.com and use code BGF10 for 10% off.
ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off.
ButcherBox: Premium, responsibly sourced protein delivered to your door, from 100% grass-fed beef to pasture-raised chicken and wild-caught seafood. New customers get a free protein for a year, plus $20 off the first box and free shipping, at ButcherBox.com/BEN.
Larine: A better-for-you chewing gum that uses nano-hydroxyapatite, the same mineral your tooth enamel is made of, to support stronger teeth and fresher breath. Visit BuyLarine.com/BEN to get up to 50% off your order.
Nuchido: Nuchido TIME+ is a science-backed supplement that optimizes your body's NAD metabolism across multiple pathways to support energy, cognition, recovery, and vitality. Visit BenGreenfieldLife.com/Nuchido and use code BEN20 to save 20%.
See omnystudio.com/listener for privacy information.

Full show notes: https://bengreenfieldlife.com/juliepodcast
In this episode with Julie Gibson Clark, I'm highlighting a throwback conversation because the gap it exposed has only gotten wider. There's a leaderboard called the Rejuvenation Olympics where people submit a blood test that measures how fast they're aging. When we recorded, Julie was a 55-year-old single mom in Phoenix making under $100,000 a year, sitting at number two in the world, aging at roughly two-thirds the speed of the calendar, and ahead of people like Bryan Johnson, who was spending $2 million a year chasing the same number. Her budget was $27 a month for a gym membership and $79 a month for a supplement. This February, Bryan Johnson opened an elite longevity program at $1 million a year with three spots, an interview process, and a requirement that you hire a dedicated assistant to keep up with the protocol.
You'll learn what Julie actually does: sleep protected like it's sacred, walking and rucking, strength training and VO2 max work, a pile of vegetables every day, one supplement, prayer, and stillness. Nothing that requires an executive assistant. You'll also hear her full health history, from heavy metal toxicity and chelation therapy to the genetics that shaped her approach, exactly what she eats and when, her supplement stack, her sleep and sauna routines, and why she refuses to name a target lifespan. Now 56 and teaching as founding faculty at a longevity academy, Julie is proof that the affordable end of longevity practice still gets you remarkably far.
Episode Sponsors:
Dr. Murray Natural Products – ThymoQuin®: A clinically researched black seed oil that supports healthy cortisol levels, resilience to everyday stress, and overall well-being, and the only one that meets U.S. Pharmacopeia guidelines. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products.
ZBiotics Pre-Alcohol Probiotic: The world's first genetically engineered probiotic that helps break down the toxic byproduct of alcohol so you can enjoy your night out and feel great the next day. 100% money-back guarantee and 15% off your first order at zbiotics.com/BEN15.
Tiny Health: An at-home microbiome test that uses metagenomic sequencing to analyze your full gut ecosystem and give personalized, evidence-based diet, lifestyle, and supplement recommendations. Get $50 off your first kit at TinyHealth.com/BEN.
ULTRA: A clean, nicotine-free, caffeine-free pouch that delivers smooth, sustained energy and focus using clinically backed nootropics and adaptogens, without the jitters or crash. Visit takeultra.com and use code BENGREENFIELD for 15% off.
TruDiagnostic: An advanced at-home epigenetic test measuring over a million biomarkers for personalized, data-driven insights into your aging, energy, and overall health. Visit TruDiagnostic.com and use code BEN20 for 20% off.
See omnystudio.com/listener for privacy information.