Longevity Optimization with Kayla Barnes-Lentz

Muscle is not just something you build in the gym. Dr. Gabrielle Lyon has spent her career arguing it's the organ that actually determines how well you age, and almost none of us have been taught to think about it that way.
Dr. Gabrielle Lyon, DO, is the founder of Muscle-Centric Medicine and the New York Times bestselling author of Forever Strong. She's spent over two decades studying muscle as the most overlooked organ in medicine.
The line that stuck with me most: she believes we're on track to trade an obesity epidemic for a sarcopenia epidemic, and most people won't see it coming until it's already happened. It's the kind of prediction I can't stop turning over, especially knowing how many women are on these medications right now without anyone telling them how to protect their muscles while they're on them. 
Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.
https://kayla-barnes-lentz.circle.so/checkout/become-a-member
This conversation explores:
Why muscle, not weight, decides how you age

Why most women are not eating enough protein

The protein habit most people get backwards

Why menopause doesn't have to mean muscle loss

What GLP1 users need to know to protect muscle

Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054
Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Learn more about Dr. Gabrielle Lyon:YouTube: https://www.youtube.com/@DrGabrielleLyon
Instagram: https://www.instagram.com/drgabriellelyon/
X: https://x.com/drgabriellelyon
Website: https://drgabriellelyon.com/

#longevity #musclecentricmedicine #muscle #proteinintake #strengthtraining #womenslongevity #sarcopenia #menopause #perimenopause #womenshealth #hormonereplacement #longevityoptimization #biohacking #GLP1

Brain aging does not start when memory loss shows up. It starts around age 25, decades before anyone notices anything is different. By the time a symptom appears, the window for the highest-leverage prevention has usually already closed.
Today I'm talking with Dr. Christin Glorioso, an MD and PhD who has spent her career studying Alzheimer's, partly because of her own family history and partly because she carries the ApoE4 gene herself. She has since used her own brain scans, blood work, and lifestyle changes to lower her own brain age, and she's built a company around helping other people do the same.
This conversation covers what actually causes Alzheimer's versus what we got wrong for decades, why the brain can grow back the same way muscle does, and why a ten minute daily habit has better evidence behind it than any drug currently on the market. We also get into hormone therapy, cholesterol, the ketogenic diet, and why women are so consistently underserved on all three.
Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.
https://kayla-barnes-lentz.circle.so/checkout/become-a-member
Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054
Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Learn more about Dr Christin Glorioso, MD, PhD
LinkedIn: https://www.linkedin.com/in/christin-glorioso-md-phd-39627719/ 
Website: https://www.neuroagetx.com/
#BrainHealth #AlzheimersPrevention #DementiaPrevention #BrainAging #Neuroscience #CognitiveHealth #HRT #Perimenopause #Menopause #Cholesterol #Nootropics

Most people think of the gut as a digestive organ. It is not. It is the upstream controller of your metabolism, immune function, brain health, skin, and hormones and almost everyone is running it on a depleted, misfed microbiome without knowing it.
Dr. Colleen Cutcliffe, PhD is the co-founder and CEO of Pendulum Therapeutics, holds a PhD in biochemistry from Johns Hopkins, and spent over 15 years in pharma and biotech before pioneering next-generation probiotic science. Her team was the first in the world to manufacture Akkermansia, a strain found at high levels in virtually every centenarian population studied and depleted in almost every major chronic disease. 
What makes this conversation different from most gut health discussions is the level of scientific rigor behind it. This is not wellness theory. This is published research, clinical data, and a decade of actually building the science from the ground up.
Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.
https://kayla-barnes-lentz.circle.so/checkout/become-a-member
In this conversation we explore:
How your gut produces its own GLP-1 naturally and why synthetic versions may blunt that system over time

Why Akkermansia is elevated in centenarians and depleted across virtually every chronic disease

The fiber gap: 95% of people are under-threshold and it is driving metabolic and colon health decline

What early antibiotic use does to the microbiome and how to rebuild at any age

Why soap may be fueling the allergy and asthma epidemic by stripping the skin's protective barrier

How butyrate links gut health, colon cancer risk, and natural GLP-1 production

Why most probiotics on Amazon do not contain what the label claims

Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054
Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Learn more about Dr Coleen
Instagram: https://www.instagram.com/drcolleencutcliffe/
Pendulum Life Instagram: https://www.instagram.com/pendulumlifeco/
Website: https://pendulumlife.com/

Dr. Elizabeth Yurth, co-founder of Boulder Longevity Institute, is one of the rare physicians who spent 30 years in orthopedic and sports medicine before pivoting to longevity and regenerative medicine. This episode covers joint health in women, osteoarthritis, bone density, peptides, perimenopause, hormones, mitochondrial health, and the regenerative protocols most women have never been offered.
What she found after decades of patching people together: we have been thinking about joint disease completely wrong. Osteoarthritis is not a wear and tear condition. It is a metabolic disease driven by mitochondrial dysfunction, hormonal decline, and chronic low-grade inflammation, and it can be prevented, slowed, and in many cases reversed if you start addressing it at the root.
Most women wait until something breaks before paying attention. By then, the damage has been building for years. The interventions that actually work are available now. They are just not in the standard conversation.
Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.
https://kayla-barnes-lentz.circle.so/checkout/become-a-member
In this conversation we explore:
Why osteoarthritis is not a wear and tear disease and what the research actually shows

How progesterone protects your ligaments, tendons, and bone (and why estrogen gets all the credit)

Why birth control creates the perfect storm for joint and ligament injury

Why mitochondrial dysfunction is at the root of joint disease, muscle loss, and brain decline and why you have to repair before you rev

Hip fractures carry a 25% mortality rate in women, and most have never had a DEXA scan

Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054
Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Learn more about Dr. Elizabeth Yurth:
Website: https://boulderlongevity.com/ 
Instagram: https://www.instagram.com/dryurth/
YouTube: https://www.youtube.com/@dryurth 
#longevity #womenslongevity #peptides #jointhealth #bonedensity #musclebuilding #mitochondria #regenerativemedicine #perimenopause #womenshealth #biohacking #osteoarthritis #hormones #longevityoptimization

Sleep is not just something women need more of. It is something women struggle with in ways that are fundamentally different from men and almost nobody explains why.
Dr. Wendy Troxel, PhD is one of the most respected sleep scientists in the world. Her research has shaped sleep policy in the US military. Her book, Sharing the Covers, is one of the most practical and science-backed guides to partnered sleep available. She is the rare researcher who can speak to the biology of sleep, the hormonal shifts of perimenopause, and what is actually happening in your bedroom, all in the same conversation.
This episode is sponsored by Zen Basil. Their certified edible basil seeds are designed for human nutrition, deliver 15g of fiber per serving, and are batch-tested for glyphosate and over 400 pesticides. 
Use the code KAYLA20 for 20% off.
https://zenbasil.com/shopzenbasil/zenbasilseedbag

Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women’s health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you’ll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.
https://kayla-barnes-lentz.circle.so/female-longevity-community
In this conversation:
Why women are twice as likely to have insomnia as men

What the new sleep duration research actually says (and why the magic number is not the point)

How relationship quality affects women's sleep and long-term health differently than men's

Why perimenopause is a perfect storm for sleep disruption

The 5 things that most reliably improve sleep quality

Connect with Kayla:
Instagram: https://www.instagram.com/kaylabarnes/
TikTok: https://www.tiktok.com/@femalelongevity
Twitter:https://x.com/femalelongevity
Website:https://www.kaylabarnes.com/
Spotify:https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054
Apple:https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227
Follow Her Female Protocol: https://www.protocol.kaylabarnes.com
Connect with Dr Wendy:
Instagram: https://www.instagram.com/drwendytroxel/ 
Website: https://www.drwendytroxel.com/
LinkedIn: https://www.linkedin.com/in/dr-wendy-troxel  
Shownotes:
Society of Behavioral Sleep Medicine: https://www.behavioralsleep.org
Dr. Wendy Troxel's TEDx Talk:
https://youtu.be/G0Zj_InJ4BQ?si=4-p3Iac2gItHlxtX