Powered by RND
PodcastsHealth & WellnessThe Empowering Neurologist Podcast
Listen to The Empowering Neurologist Podcast in the App
Listen to The Empowering Neurologist Podcast in the App
(471)(247,963)
Save favourites
Alarm
Sleep timer

The Empowering Neurologist Podcast

Podcast The Empowering Neurologist Podcast
David Perlmutter
The Empowering Neurologist is an interview series with some of the most exciting thought leaders in the field of health and wellness.

Available Episodes

5 of 197
  • How to Make Your Brain Ageless: Prevent Cognitive Decline & Supercharge Your Mind - with Dale Bredesen | EP 197
    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.comThe idea that we can live however we want and then rely on a magic treatment for cognitive issues is unrealistic and dangerous. The reality is that our daily choices profoundly impact our brain’s future, and once cognitive decline begins, there is no clear-cut pharmaceutical solution.I had the pleasure of speaking with Dr. Dale Bredesen, whose book The Ageless Brain is an incredible resource for protecting brain health. He has pioneered a comprehensive approach to preventing and even reversing cognitive decline. This book offers a powerful blueprint not only for sharpening your mind but also for building resilience against neurodegenerative diseases.In The Ageless Brain, Dr. Bredesen distills decades of research into actionable steps. He explores key lifestyle factors—nutrition, sleep, exercise, stress management, and supplementation—that influence cognitive performance and long-term brain resilience. What’s exciting is his proactive, personalized approach. Rather than waiting for symptoms to appear, Dr. Bredesen shows us how to build a brain that resists aging from the start.Today, we’ll unpack some of the most impactful strategies from his book, discuss major breakthroughs in neuroscience, and explore how we can all take charge of our cognitive health. If you’ve ever wondered what it takes to maintain lifelong clarity and vitality, you won’t want to miss this conversation.Dale Bredesen, MD, is an internationally recognized neurologist specializing in neurodegenerative diseases. He is the Senior Director of Precision Brain Health at Pacific Neuroscience Institute® and the Chief Scientific Officer at Apollo Health.Guided by his belief that Alzheimer’s is not just preventable but reversible, Dr. Bredesen’s groundbreaking research has helped explain the biological mechanisms behind memory loss. His decades of study have led to new treatment approaches, including the ReCODE Protocol™—also known as the Bredesen Protocol—a strategy designed to prevent, slow, and even reverse cognitive decline associated with Alzheimer’s, dementia, and mild cognitive impairment.Timestamps:0:00 Introduction to Guest2:48 Phase 3 Trial Upcoming10:11 Alzheimer’s: Different Triggers, Different Outcomes13:11 Could Brushing Your Teeth Save Your Brain? (Oral Microbiome & Alzheimer’s18:45 The 3 Major Players in Brain Health22:24 How to Make Sure You Never Get Dementia22:33 Blood Markers for Alzheimer’s: What Your Tests Reveal28:10 Diabetes and Alzheimer’s: The Hidden Connection34:18 The #1 Contributor to Cognitive Decline: Insulin Resistance39:54 How to Match Your Brainspan to Your Lifespan40:31 Top Supplements for Brain Health43:15 The Power of Nitric Oxide for Your Brain48:07 Leaky Gut & Cognitive Decline54:15 Metformin & Brain Longevity57:31 Why Do More Men Than Women Get Parkinson’s1:05:24 ADHD & Alzheimer’s: The Fruit Fly Discovery ("Alzflymers")___________________________Dale Bredesen, M.D., is an expert in neurodegenerative diseases such as Alzheimer’s. He is a graduate of Caltech and received his MD from Duke University Medical Center. His career includes serving as Chief Resident in Neurology at UCSF, working as an NIH Postdoctoral Fellow, and holding faculty positions at UCSF, UCLA, and UC San Diego. He was the director of the Program on Aging at the Burnham Institute and the founding President and CEO of the Buck Institute. His work has led to a new therapeutic approach for treating Alzheimer’s. He is the author of The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline.___________________________Instagram: https://www.instagram.com/davidperlmutter/Website: https://www.drperlmutter.com/Subscribe to our channel: https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
    --------  
    1:09:07
  • The Stress Paradox: How to Harness Pressure for a Stronger, Healthier Life - with Sharon Bergquist | EP 196
    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱Yes, we need stress in our lives! Staying in our comfort zone may be doing us more harm than good. That’s probably surprising to hear from me having spoken about the importance of reducing stress over the years. But, nonetheless, a level of stress that is not overly damaging, and that may actually have positive benefits. Today we are going to learn much more about that will be looking at the book, The Stress Paradox with Dr. Sharon Horesh Bergquist. We're going to learn about the"Stress dilemma" that we face, how stress enhances, cellular resilience, how our life compares to the lives of our ancestors in terms of the physical stresses that we endure. We will explore how stressing ourselves in relation to the times that we eat, our physical exercise, and even explore how sleep or lack of sleep, may affect us in negative and even perhaps positive ways. All in all, we"re learning these days how we want to do our best to leverage the value of being out of our comfort zone but also recognizing ourboundaries. 00:00 Introduction02:00 Welcoming Sharon and Introducing The Stress Paradox06:33 Sleep is Critical07:12 Good Stress (HIIT) vs. Bad Stress (Financial Hardship)09:50 Hormetic Stress? Current Environment vs. Ancestors' Stress Levels13:20 Stress Responses Stored in Phytochemicals and our Evolutionary Relationship with Plants19:01 10,000 DNA Injuries Any Given Day, 7 Per Minute22:03 The Biggest Factor Related to Longevity26:01 Relationship with Decreased Risk of Alzheimer’s & The Role of Myokines30:17 Microglia Cells Can Share Mitochondria (Before & After)35:13 Heat Exposure Mimics the Benefits of Exercise38:01 Key Strategies for Longevity and Vitality45:32 Personalized Health Strategies for Optimal Performance50:25: The Cortisol Spike and Why It is Necessary 58:20 Why You Need Non-negotiables In Your Physiology50:20 Conclusion====Sharon Horesh Bergquist, MD, is an award-winning physician, innovative healthcare leader, and visionary researcher renowned for spearheading a science-based approach to applying lifestyle as medicine. She has helped lead numerous clinical trials, including the Emory Healthy Aging Study and the NIH funded Emory Healthy Brain Study. Dr. Bergquist is widely published in peer-reviewed journals and has contributed to over 200 news___________________________Instagram: https://www.instagram.com/davidperlmutter/Website: https://www.drperlmutter.com/Subscribe to our channel:https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
    --------  
    1:00:37
  • Yes, Stress Can Be Good: The Health Benefits of Doing Hard Things - with Jeff Krasno | EP 195
    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱We all want to live a stress-free life. But as it turns out, this may not necessarily be in our best interest having a low level of stress of various types turns out to be good for our physiology and can even help us recover from illness. When stress is implemented in this way, it is termed, other words, the upside of low-grade stress. That stress can be exercise, immersion ourselves in cold or hot temperatures, time restricted eating, or even various forms of light exposure all of which we will explore on my podcast today, which is an interview with my good friend, Jeff Krasno. His new book, Good Stress, that he wrote along with his wife Schuyler GrantHe is the CEO and founder of Commune Media, a masterclass platform for well-being that features renowned authors and teachers. He hosts the Commune podcast, which has over 520 episodes and generates more than 750,000 monthly downloads, featuring interviews with luminaries such as Deepak Chopra, Marianne Williamson, Matthew McConaughey, and Gabor Maté. Additionally, Jeff writes a weekly "Commusing" essay exploring well-being, spirituality, and culture, distributed to an email list of over one million subscribers.Prior to founding Commune Media, Jeff co-created Wanderlust, a global series of wellness events that have significantly contributed to popularizing yoga practices and principles in the U.S. and beyond. In 2016, Oprah Winfrey selected him as part of the SuperSoul100, recognizing him as one of the nation's leading entrepreneurs.Jeff's latest book, "Good Stress: The Health Benefits of Doing Hard Things," co-authored with his wife, Schuyler Grant, is set to be released on March 25, 2025. I've had the opportunity to read the galley and it's a terrific book that will open a lot of doors for each and every one of you in terms of regaining your health.TIMESTAMPS00:00 Introduction and Personal Connection with Jeff Regarding the Los Angeles Wildfires8:51 Introducing Jeff’s Book, Good Stress: The Health Benefits of Doing Hard Things13:42 The Personal and Societal Costs of Poor Health18:27 Jeff’s Background and Personal Approach to Wellness22:54 Homeostasis as the Foundation of Health25:42 Rethinking "Normal"—The Flaws of the Bell Curve Perspective29:24 Evolutionary Perspectives on Health and Adaptation34:55 Thermoregulation as a Pathway to Homeostatic Flexibility38:15 Hypoxia and Its Role in Physiological Adaptation47:04 The Therapeutic Potential of Thermal Shock49:51 The Concept of Good Stress and the Evolutionary Mismatch of Modern Lifestyles55:01 Optimal Timing and Approaches for Cold Plunging1:00:46 Jeff’s Personal Biohacking Journey1:07:08 Exploring the Benefits of Light Therapy and the Revival of Raw Milk Consumption====Jeff Krasno is the co-founder and CEO of Commune, a masterclass platform for personal and societal well-being and co-creator of Wanderlust, a global series of wellness events. He hosts the Commune podcast, interviewing a wide variety of luminaries from Deepak Chopra and Marianne Williamson to Matthew McConaughey and Gabor Maté. His latest venture expands Jeff’s personal story and protocols into a book, Good Stress: The Benefits of Doing Hard Things (Hay House, March 2025). The book dives deeper into the concepts from the course, distilling insights from over 400 podcast conversations Jeff has conducted, along with his personal experiences applying these ideas to transform his own health. It explores deliberate, self-imposed behaviors that promote social, psychological, and physical well-being, offering both a philosophical exploration of true wellness and practical steps to achieve it.Instagram: https://www.instagram.com/davidperlmutter/Website: https://www.drperlmutter.com/Subscribe to our channel:https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
    --------  
    1:20:54
  • Is Lifting Weights the Best Dementia Prevention? Muscle’s Impact on Brain Health - with Dr. Austin Perlmutter | EP 194
    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱We all know that exercise is good for the body and specifically, very good for the brain. In fact, exercise is the most important inroad to better brain health, better brain function, protecting the brain against decline, and even with respect to mood issues like depression.But it's reasonable to ask how in fact does this work? How is it that exercising muscles does good things for the brain?On today's episode of the Empowering Neurologist we spent time with Dr. Austin Perlmutter. He takes us on a deep dive exploring the exact connection between muscle and its endocrine function in terms of creating various chemicals that are so helpful for better brain health. It's a great discussion that looks at things like how much exercise is appropriate, what type of exercise is best, how much protein we should be consuming, and what other supplements will augment the benefits of exercise in terms of better brain health. I think you will really enjoy this episode. I know I sure did, after all, getting to spend time with my son is always special!=====00:00:00 Introduction & Welcoming Dr. Austin00:01:56 The Relationship of Muscle Health, Mental Health, and Brain Health00:09:15 The Power of Exercise to Improve Cognition vs Pharmaceuticals & The Muscle as an Endocrine Organ00:16:36 The Molecules Produced by Muscles: Myokines 00:20:10 Myokines, Inflammation, and Metabolic Health 00:26:43 Sarcopenia and The Risk of Dementia00:31:50 Brain Derived Neurotropic Factor, Neuroplasticity & Weight Training 00:39:40 Animal versus Plant Protein to Build Healthy Muscle00:46:26 Cycling Anabolic and Catabolic States00:51:31 Why Women Are 2x More Likely to Develop Alzheimer's and What Supplementation Is Necessary to Compliment Building Muscle01:05:40 Conclusion and Wrap Up=====Dr. Austin Perlmutter is a board-certified internal medicine physician, New York Times bestselling author, researcher, educator, podcaster and entrepreneur. His mission is to help people get their brains unstuck for better mental and cognitive health. Dr. Perlmutter’s work on how environment and diet influences brain health has been featured on PBS, Rolling Stone, Newsweek, NPR, Fox, CBS and other top media outlets. He has co-produced and hosted some of the world’s largest online brain health events including Alzheimer’s, the Science of Prevention and the Better Brain Blueprint. He is the Managing Director of Big Bold Health, where he led a pioneering study exploring plant nutrient effects on human aging. He is the CEO of Lichen Air, which provides science-backed indoor air solutions for better brain health and longevity. He is also a research consultant to the Helfgott Research Institute, where he studies the epigenetic, metabolic, microbiome and immune effects of ayahuasca. Website: https://www.austinperlmutter.com/YouTube: https://www.youtube.com/@draustinperlmutterIG: https: https://www.instagram.com/draustinperlmutter/Lichen AIr: https://lichenair.com/Dr. Austin Perlmutter's Muscle-Brain eGuide: https://www.austinperlmutter.com/muscleguide___________________________Instagram: https://www.instagram.com/davidperlmutter/Website: https://www.drperlmutter.com/Subscribe to our channel:https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
    --------  
    1:07:01
  • Treating Alzheimer’s with Light and Sound - with Christian Howell | EP 193
    🧠 Stay ahead with the latest in science, nutrition, and wellness by subscribing to Dr. Perlmutter’s newsletter at: www.drperlmutter.com. ✉️🌱Over the last several decades, it’s been interesting to watch the progression of ideas for treating Alzheimer’s change from focusing on brain chemistry to targeting the accumulation of proteins in the brain associated with the disease. Recently, there’s been exciting interest in studying how the brain’s electrical circuits and rhythms change in Alzheimer’s and other brain degenerative disorders.The human brain operates in rhythms, with gamma frequencies playing a critical role in cognitive functions such as memory, attention, and learning. In neurodegenerative diseases like Alzheimer’s, these gamma oscillations are disrupted, contributing to the accumulation of harmful proteins such as amyloid-beta and tau. Cognito Therapeutics has developed a pioneering approach using non-invasive light and sound stimulation to restore these rhythms and trigger natural mechanisms for clearing these toxic proteins.In preclinical and early clinical trials, this method has demonstrated remarkable potential. By stimulating gamma oscillations, the therapy has shown the ability to reduce inflammation, enhance synaptic function, and activate microglia—immune cells responsible for clearing debris and maintaining brain health. For families battling cognitive decline, these results offer hope for improving quality of life and potentially slowing disease progression. Cognito’s research focuses on safety, accessibility, and scalability. Unlike pharmaceutical interventions, this approach avoids invasive procedures or systemic side effects, making it an attractive alternative or complementary treatment for Alzheimer’s.As the company advances its clinical trials, the implications extend far beyond Alzheimer’s. Cognito’s technology could pave the way for treatments for neurological conditions like Parkinson’s, MS, and traumatic brain injury.On our podcast today, we are joined by Christian Howell, CEO of Cognito Therapeutics. Howell is committed to advancing the understanding of brain health and delivering groundbreaking therapeutic solutions to improve patient outcomes. Under his leadership, Cognito Therapeutics has made significant strides in the development of gamma-frequency neuromodulation technologies, leveraging light and sound stimulation to address the mechanisms of Alzheimer’s and other neurodegenerative disorders. Howell is a strong advocate for translating cutting-edge research into real-world applications and has spearheaded the company’s efforts to validate its therapies through rigorous scientific studies and clinical trials.Howell holds advanced degrees in neuroscience and bioengineering and has dedicated his career to bridging the gap between scientific discovery and patient care. His work reflects a commitment to improving the lives of individuals and families impacted by cognitive decline and to shaping the future of brain health through innovation and collaboration.====00:00 Introduction00:59 Optogenetic Light & SoundTherapy 11:28 Innovations in Light and Sound Therapy at 40Hz Interval; Generating Neuroplasticity17:48 Rethinking Alzheimer’s Treatment and Gamma Wave Stimulation’s Impact on Proteins20:43 Overview of Cognito Therapeutics at Home Device25:30 Usage for Therapeutic, Preventative, and Performance Enhancement. 28:37 Disease States: Dysregulation of Microglia; Long Covid, Chemo Brain, Sepsis 30:45: Breakthrough Designation from FDA For the Device38:07 FDA Approval, Distribution, and Insurance Approval; Economic Burdens of Alzheimer’s 44:30 Closing Insights on Revolutionary Therapies====Instagram: https://www.instagram.com/davidperlmutter/Website: https://www.drperlmutter.com/Subscribe to our channel:https://www.youtube.com/channel/UCDRl_UAXxbHyOOjklnA0dxQ/?sub_confirmation=1
    --------  
    49:45

More Health & Wellness podcasts

About The Empowering Neurologist Podcast

The Empowering Neurologist is an interview series with some of the most exciting thought leaders in the field of health and wellness.
Podcast website

Listen to The Empowering Neurologist Podcast, Wisdom & Wellness with Mpoomy Ledwaba and many other podcasts from around the world with the radio.net app

Get the free radio.net app

  • Stations and podcasts to bookmark
  • Stream via Wi-Fi or Bluetooth
  • Supports Carplay & Android Auto
  • Many other app features
Social
v7.11.0 | © 2007-2025 radio.de GmbH
Generated: 3/25/2025 - 6:13:08 PM