The Hunter Williams Podcast

• Why You’re Stuck: GLP-1 Plateaus (And How to Break Through)

  Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/In this video, I dive deep into the reasons behind the infamous “GLP plateau”—that frustrating point where fat loss on GLP-1 peptides like semaglutide, tirzepatide, and retatrutide comes to a grinding halt. I break down the physiological, hormonal, and lifestyle factors that drive plateaus, plus practical, science-backed solutions to get results moving again.⸻Timestamps0:00 – Introduction: Why Do GLP-1 Plateaus Happen?0:35 – Why Weight Loss Plateaus Are Universal1:22 – How GLP-1s Work (Mechanisms: Semaglutide, Tirzepatide, Retatrutide)2:36 – Typical Weight Loss Trajectory on GLP-1s3:18 – When (and Why) Most People Plateau4:55 – Plateau ≠ Failure: The New Weight Set Point5:39 – Physiological & Metabolic Causes of Plateaus6:26 – Resting Metabolic Rate Drop & Adaptive Thermogenesis7:31 – Decreased Thermogenesis, Exercise Efficiency, & Mitochondria8:42 – Muscle Loss and Its Impact on Plateaus9:44 – NEAT (Non-Exercise Activity Thermogenesis) Drops10:18 – Why the Body Adapts: Our Ancestral Survival Mechanism11:06 – Hormonal Adaptations: Leptin, Ghrelin, Insulin13:03 – Leptin Drop: Increased Hunger, Lower Metabolism13:41 – Ghrelin Rise: Appetite Returns15:17 – Insulin, Metabolic Health & Fat Loss17:20 – Thyroid Hormones: T3, Metabolic Rate, and the Plateau19:03 – Cortisol, Stress, and Fat Storage20:07 – Sex Hormones: Testosterone, Fat Loss, and Plateaus21:46 – Amylin, Neuropeptide Y, and Brain Pathways22:44 – Behavioral & Lifestyle Factors: NEAT, Adherence, Calorie Creep24:44 – Psychological Fatigue, Sleep, Diet Quality, & Hydration28:27 – Is It a True Plateau? Body Fat vs. Weight Loss28:32 – Pharmacological Tolerance & Dosing Issues30:00 – Appetite Pathways and Receptor Desensitization31:52 – Dose Ceiling: When More Isn’t Always Better33:26 – Strategies to Break Through a Plateau34:16 – Re-evaluating Diet: Macros, Sugar Diet, and Tracking34:45 – Activity, Resistance Training, and NEAT35:03 – Sleep, Stress, Thyroid, and Other Medications35:44 – Add-On Pharmacology: LDN, Cagrilintide, Leptin Analogs37:01 – Mitochondrial Pathways: BAM15, SLU-PP-332, Carnitine37:50 – Cycling, Refeeds, and Metabolic Resensitization39:55 – Fasting, Intermittent Fasting, and Nutrition40:08 – Recap: Everyone Plateaus—How Will You Respond?41:02 – Thank You & Outro

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  41:23
• GLP-1 Fatigue: Why You’re Tired & How to Get Your Energy Back

  Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/If you’re struggling with fatigue, low motivation, or brain fog while on GLP-1 agonists like tirzepatide or retatrutide, you are NOT alone! I get asked about “GLP-1 fatigue” constantly, and in this video, I dive deep into why so many people experience tiredness on these meds, the science behind it, and—most importantly—what you can do to overcome it and get your energy back.I cover everything from calorie restriction and dehydration to hormone and mitochondrial slowdown, and even the toxic load released during rapid fat loss. Whether you’re new to GLP-1s or have hit an energy wall, this is the comprehensive review you need!Timestamps:0:00 – Intro: Why are GLP-1 users so fatigued?1:33 – What are GLP-1s, and why do people use them?2:30 – How common is fatigue on GLP-1s?3:24 – Who gets prescribed GLP-1s and why fatigue might be worse for some4:10 – Calorie restriction and appetite suppression5:43 – Metabolic adaptation: Why your metabolism slows down6:20 – Nutrient deficiencies and low protein7:37 – Weight loss itself: Why rapid fat loss can make you feel weak7:41 – Dehydration and electrolyte imbalances8:39 – Reduced thirst and GI side effects9:56 – Blood sugar fluctuations and hypoglycemia11:03 – Brain effects: Dopamine, mood, and motivation12:15 – Hormonal changes: Leptin, thyroid, testosterone13:40 – Neurological factors: GLP-1 in the brain15:49 – The “detox effect” of rapid fat loss17:06 – How toxin release and inflammation cause fatigue18:47 – Mitochondrial slowdown: Why you feel so flat20:45 – Practical fixes: What to do about GLP-1 fatigue22:57 – How to eat, hydrate, and adjust your dose24:15 – Timing your injections and microdosing25:30 – Circadian rhythm, sunlight, and lifestyle tips26:42 – Closing thoughts and community feedbackIf you’ve experienced fatigue or brain fog on GLP-1s, comment below—share what worked for you! And if you want a deeper dive into peptides, hormones, and biohacking, grab my free peptide cheat sheet in the description and join Fully Optimized Health, the best community for health optimization.Thank you for being here—I’m grateful for every one of you! If you found this helpful, like, comment, and subscribe for more science-backed content.

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  27:59
• Why The Sugar Diet Works: My Results, Full Protocol & Science Explained

  Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Discover My Experience With The Sugar Diet: Results, Protocol, and The Truth About Carbs!0:00 - Introduction: What Is the Sugar Diet?0:46 - Shout Out to Mark Bell & How I Found Out About the Sugar Diet1:57 - Why Everyone’s Sugar Diet Will Look Different3:13 - My Sugar Diet Protocol: Reasoning and Methodology4:12 - The Science: FGF-21 and Rethinking Carbs6:32 - The Problem with Keto and Low-Fat Dogma7:20 - What Is the Sugar Diet? Four Core Pillars8:39 - Why the Sugar Diet Works: Mechanisms and Flexibility10:11 - How to Implement the Sugar Diet10:42 - My Training Day Meal Plan13:42 - The Pre-Workout Carb Protocol15:31 - Training Approach: High Rep, Short Rest, Push/Leg/Pull16:14 - Post-Workout Nutrition: Protein, Carbs, and Glycogen17:46 - Lunch and Dinner Strategies19:23 - Protein Sources and Starch Choices20:46 - Evening Snack: Carbs Before Bed, Sleep Benefits21:48 - Cardio/Fasting Days and “Sugar Fasting”22:41 - What I Eat On Cardio Days24:44 - Fasted Cardio vs. Carbs Before Cardio25:27 - Protein Cycling Windows & Maximizing Results27:02 - Saturday Cheat Meal and Flexibility28:27 - My Sunday Fasting Routine29:44 - The Importance of Refeed Meals30:31 - Macro Targets and Weekly Structure31:08 - Specific Food Choices and Training Recap33:44 - Example Macro Breakdown for Training and Fasting Days35:01 - Starch as a Lever for Rate of Fat Loss35:53 - How to Adjust for Muscle Growth or Fat Loss36:16 - Final Thoughts: What’s Working and How I’m Tweaking36:23 - Results After Two Weeks: Weight, Aesthetics, and Energy37:04 - Community: Sharing Experiences & Your Questions37:46 - Thank You & Closing Thoughts⸻Welcome! I’m Hunter Williams and today I’m breaking down everything you need to know about the sugar diet, my personal protocol, and why this approach is changing the fitness and weight loss world. After following the sugar diet for several weeks (inspired by Mark Bell), I’m sharing my real-world results, the science behind why carbs (especially sugar!) can actually accelerate fat loss, and how you can adapt the diet to your goals—whether you want to lose fat, build muscle, or maximize metabolic health.In this video, you’ll learn: • Why the “sugar diet” isn’t about eating junk food but optimizing carb intake for hormone health (FGF-21!) • The best foods to eat and what to avoid for metabolic flexibility • How to set up your training and cardio days for maximum fat loss • How to cycle protein and fat for best results • Why so many people—including former keto and carnivore followers—are losing weight faster than everI lay out my exact meal plan, explain the science in simple terms, and show you how to make the sugar diet work for you. Whether you want to drop fat, keep muscle, or just feel amazing, this is your no-BS guide to the sugar diet.

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  38:20
• Struggling with Fatigue? My Go-To Peptide Stack for Instant Energy

  Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Feeling drained, exhausted, or battling chronic fatigue? In this video, I’m sharing a powerful peptide stack that I personally tested to boost energy dramatically. After a grueling weekend of minimal sleep and maximum stress from my recent wedding, I found myself desperately needing an energy kick to handle a demanding work week.I combined three potent peptides—MOTS-c, NAD+, and Injectable 5-Amino-1MQ—to create a synergistic energy-enhancing formula. The results blew me away. Not only did my energy soar, but my cognitive clarity and physical performance significantly improved.Watch this video as I detail my exact dosages, injection methods (subcutaneous and intramuscular), and the science behind why this peptide combo works so effectively. Whether you’re recovering from stressful events, jet-lagged from travel, or simply need more daily energy, this peptide stack is a game changer.Timestamps:0:00 - Why I Created My Energy-Boosting Peptide Stack1:03 - How My Wedding Weekend Left Me Drained2:27 - Discovering the Peptide Combo (MOTS-c, NAD+, 5-Amino-1MQ)3:43 - My Exact Peptide Dosages and Mixing Method4:46 - Incredible Energy Results from the First Injection5:34 - Intramuscular vs. Subcutaneous Injection: My Experience6:31 - Is This Peptide Stack Safe to Mix?7:37 - How Each Peptide Enhances Energy and Mitochondrial Health8:17 - Additional Benefits: Energy and Fat Loss Potential9:00 - Who Should Use This Peptide Stack? (Fat Loss, Chronic Fatigue, Low Energy)

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  10:26
• Why I Inject Estrogen | New TRT Protocol Explained

  Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/👉Join The Fully Optimized Health Private Membership Group: https://www.fullyoptimizedhealth.com/start-here1 On 1 Coaching Application: https://hunterwilliamscoaching.carrd.co/Book A Call With Me: https://hunterwilliamscall.carrd.co/Supplement Sources: https://hunterwilliamssupplements.carrd.co/Amazon Storefront: https://www.amazon.com/shop/hunterwilliams/list/WE16G2223BXA?ref_=cm_sw_r_cp_ud_aipsflist_R7QWQC0P1RACB2ETY3DYSocials:Instagram: https://www.instagram.com/hunterwilliamscoaching/Podcast: https://hunterwilliamspodcast.buzzsprout.com/Video Topic Request: https://hunterwilliamsvideotopic.carrd.co/Ever wonder why a man would inject estrogen alongside testosterone therapy? In this video, I dive deep into my personal experience and explain exactly why I started using injectable estrogen, how it transformed my sexual function, cognitive performance, mood, and overall quality of life.You’ll discover my journey with injectable DHT, why balancing estrogen became crucial, and how I fine-tuned my protocol to find the sweet spot. I address common misconceptions about estrogen for men, particularly for those already on testosterone replacement therapy (TRT). If you’re lean, experiencing joint discomfort, decreased libido, or cognitive sluggishness on TRT, estrogen might be exactly what your regimen is missing.Watch to the end as I share my personal dosages, bloodwork insights, and practical recommendations that you can potentially apply to your own hormone optimization journey.⸻Timestamps:0:00 - Why I Inject Estrogen (It’s Not What You Think)2:04 - My Experience with Injectable DHT4:03 - Noticing Low Estrogen Symptoms5:04 - Finding the Ideal Testosterone-to-DHT Ratio6:22 - Injectable Estrogen: A Bodybuilder’s Secret?8:25 - My First Injectable Estrogen Protocol9:51 - Amazing Benefits of Adding Estrogen to Testosterone11:28 - Importance of Body Fat Percentage and Estrogen13:06 - Why Men Fear Estrogen and Why They Shouldn’t14:25 - My Exact Estrogen Dosage and Protocol15:35 - Why Injectable Estrogen is Essential for Leaner Men17:00 - Could Estrogen Resistance Syndrome Exist?17:54 - Final Thoughts on Estrogen Benefits for Men

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  19:07

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