
Inside Metabolic Collective: Fueling Change in Mental Health
2026/1/12 | 42 mins.
The science of metabolic psychiatry is advancing, but the movement behind it is just getting started. In this episode, Dr. Bret Scher sits down with Natasha Smikles and Eddie Rodriguez from Metabolic Collective, a new nonprofit working to build an international advocacy network for ketogenic and metabolic therapies.Their goal: accelerate awareness, adoption, and support for metabolic interventions in mental health.They cover:The personal journeys that led Natasha and Eddie to metabolic therapyWhy lived experience is such a powerful driver of changeWhy Metabolic Collective was created, and who it’s forHow Metabolic Collective is organizing community-led advocacy and educationWhat tools, resources, and events are available to help you get involvedHow to support others, start a local group, or bring metabolic psychiatry into your communityMetabolic psychiatry is growing, and movements like this are helping close the gap between research and real-world impact. From mental health challenges to neurological disorders, the Metabolic Collective hopes to spread the word about metabolic therapies and empower patients with alternative options to standard of care.👉Learn more about the Metabolic Collective at https://metaboliccollective.org. 👉Read the Metabolic Collective case for support at https://metaboliccollective.org/case-for-support/.#MetabolicMind #KetogenicTherapy #MetabolicPsychiatry🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.Experts Featured:Natasha [email protected]://www.instagram.com/natasha.smikles/https://x.com/NatashaSmikleshttps://www.linkedin.com/in/natasha-smikles-93753523a/Eddie Rodriguezhttps://www.instagram.com/brainheal_th_/?hl=enhttps://www.youtube.com/@BrainHeal_th_https://x.com/BrainHealth919Resources Mentioned:

Q&A: Caffeine, Carnivore, Meds, and Ketones—What’s Helping or Hurting Your Mental Health?
2025/12/29 | 27 mins.
Is caffeine sabotaging your mental health progress? Should you try a carnivore diet if keto isn't working? What if your meds lower ketones?In this new Metabolic Mailbag episode, Dr. Georgia Ede joins Dr. Bret Scher to answer your most pressing questions about metabolic therapies, mental health, and more.Together, they dive into nuanced, evidence-informed conversations about:The real impact of caffeine on mood, sleep, and ketosisWhether the carnivore diet is “too high” in proteinWhy some people see mental health improvements on carnivore when a ketogenic diet hasn’t workedWhat to do when medications interfere with ketone levels, and why deprescription must be done safely and strategicallyAnd moreMetabolic psychiatry is a promising frontier, and we’re here to empower individuals navigating serious mental illness with tools and knowledge rooted in science, compassion, and real-world experience.🔎Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.🔔 Subscribe to Metabolic Mind and join the growing community exploring metabolic therapies for mental health: https://www.youtube.com/@metabolicmind#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd/https://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Change Your Diet, Change Your Mind by Dr. Georgia Edehttps://www.amazon.com/Change-Your-Diet-Mind-Powerful/dp/1538739070 Taper Down Slowly: A Beginners Guide to Psychiatric Drug Tapering (Part 1)https://www.youtube.com/watch?v=RVMvi-vU5E8 Go Slowly: A Beginners Guide to Psychiatric Drug Tapering (Part 2)

Rethinking Serotonin And Depression: What SSRIs Really Do & What May Work Better
2025/12/22 | 39 mins.
Do SSRIs help your brain?SSRI medications are among the most widely prescribed antidepressants, but what if we’ve misunderstood how they work? In this interview, Dr. Bret Scher sits down with biochemist and nutrition scientist Dr. Chris Masterjohn to explore a deeper, more systemic view of mental health and how we treat it.Dr. Masterjohn reveals why serotonin isn’t just a “mood booster,” how SSRIs may be disrupting mitochondrial function, and why focusing on lifestyle strategies that support brain energy metabolism could unlock new paths for treating depression.🔍 What you’ll learn:Chris’s personal journey from veganism to carnivoreThe importance of testing for nutrient deficienciesHow mitochondria influence mood and cognitionWhy SSRIs may disrupt brain energy metabolismThe truth about serotonin and morning sunlightWhy exercise & nutrition often outperform medicationWhat SSRIs really do (and what they don’t)If you've ever questioned the serotonin theory of depression, or sensed there’s more to the story than what mainstream medicine tells us, this conversation fills in some of the missing pieces.🔎 Have questions about how to apply metabolic therapies effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.👉 Subscribe to Metabolic Mind for more interviews, research, and updates in the field of metabolic psychiatry.Expert Featured:Dr. Chris Masterjohnhttps://www.chrismasterjohn-phd.com/https://substack.com/@chrismasterjohnphdhttps://x.com/ChrisMasterjohnhttps://www.facebook.com/chrismasterjohn/https://www.instagram.com/chrismasterjohn/Resources Mentioned:Substack: Prozac is a Performance Enhancing Drughttps://chrismasterjohnphd.substack.com/p/prozac-is-a-performance-enhancingMitome: Mitochondrial Analysishttps://www.mito.me/Free CME Clinician Trainings:Are you a clinician...

Q&A: Healthy Fats, Alcohol, Perimenopause, & More
2025/12/15 | 31 mins.
Is carb-cycling okay on a ketogenic diet? What about high histamine foods?In this episode of Metabolic Mailbag, Dr. Bret Scher and Dr. Georgia Ede answers questions on everything from the best sources of dietary fat to how to handle anxiety, perimenopause, and alcohol while maintaining ketosis.They unpack how to build a nutrient-dense, brain-supportive ketogenic diet using whole foods, why “keto-friendly” processed products can sometimes derail progress, and when supplements might be beneficial. You’ll also learn why histamine sensitivity, caffeine, or cycling in and out of ketosis can affect mood, and how to troubleshoot each.This conversation covers:Why a whole food ketogenic diet can be ideal for mental healthHow to identify the best fat sources and avoid “factory fats”Ketogenic dieting for women’s healthWhy anxiety can worsen mid-journey, and how to adaptThe truth about alcohol, carb cycling, and ketosisIf you’re exploring ketogenic therapy for mental or metabolic health, this episode offers practical, science-based guidance to help you refine and personalize your approach.🔎 Have questions about ketogenic diets or how to apply ketogenic therapy effectively? Submit them at metabolicmind.org/questions to be featured in a future Metabolic Mailbag episode.👉Stay up to date with the latest, news, insights, and research on metabolic psychiatry by subscribing to Metabolic Mind: https://www.youtube.com/@metabolicmind#MetabolicMind #KetogenicTherapy #FoodAsMedicine #QuestionAndAnswerExpert Featured:Dr. Bret Scherhttps://x.com/bschermd/https://www.linkedin.com/in/bret-scher-08baaa102/Dr. Georgia Edehttps://www.diagnosisdiet.com/https://www.linkedin.com/in/georgiaedemdhttps://www.facebook.com/GeorgiaEdeMd/https://www.instagram.com/georgiaedemd/?hl=enResources Mentioned:Dr. Bret Scher’s Carb Cycling Video: https://www.youtube.com/watch?v=b5bUc7TbS6oDr Madison Kackley: Keto for Women https://www.youtube.com/watch?v=IQ8aGNwGB9cFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:

Could Stress Be The Hidden Driver of Mental Illness?
2025/12/08 | 34 mins.
New research links chronic stress, brain energy, and psychiatric conditions, including PTSD, depression, and bipolar disorder.Stress doesn’t just impact your mood; it affects how your brain allocates energy. In this interview, Dr. Bret Scher sits down with Dr. Parker Kelly, a postdoctoral fellow at UCSF and the San Francisco VA, to unpack the Allostatic Triage Model of Psychopathology, a new framework proposing that psychiatric symptoms may emerge when the brain is forced to triage limited metabolic resources under chronic stress. Co-authored with mitochondrial researcher Dr. Martin Picard, this model could shift how we understand and treat mental illness.In this conversation, you’ll learn:How stress drives brain energy dysfunctionWhy mitochondria and metabolism may be central to mental illnessWhich brain networks are impacted by energy deficitsThe role of predictability and routine in stress resilienceHow metabolic therapies like nutrition, sleep, and even psychedelics, may support brain energy regulationThis conversation bridges neuroscience, metabolism, and mental health, offering a unique and unifying lens on complex psychiatric conditions.👉Subscribe to Metabolic Mind for more conversations about metabolic health, metabolic psychiatry, and mental health: https://www.youtube.com/@metabolicmind.#MetabolicMind #KetogenicTherapy #NeuroscienceExpert Featured:D. Parker KelleyX.com/sequencemyneurohttps://bsky.app/profile/sequencemyneuro.bsky.socialhttps://www.linkedin.com/in/dparkerkelleyphd/Resources Mentioned:The allostatic triage model of psychopathology (ATP Model): How reallocation of brain energetic resources under stress elicits psychiatric symptomshttps://doi.org/10.1016/j.neubiorev.2025.106419Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of...



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