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Live Long and Well with Dr. Bobby

Dr. Bobby Dubois
Live Long and Well with Dr. Bobby
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  • #56 Change exercise as you age?
    Send us a textExercise is the most powerful longevity tool we have, but after 50 the recovery curve, injury risk, and bone/muscle changes mean the smartest plan blends strength, power, impact, and slightly more recovery—so you can train hard without derailing progress.What we coverWhy this matters now: record-setting older endurance athletes (and I’m racing at 69) show what’s possible—if we train wisely.The “aging triad”: loss of muscle (especially fast-twitch/power), bone density shifts (sharpest around menopause), and rising osteoarthritis risk.The injury paradox: the fitter you are, the more a single layoff can cost; preventing setbacks is a longevity strategy.A practical framework: build strength, protect fast-twitch fibers, add tolerable impact for bone, and consider an extra rest day after hard sessions.Evidence, in plain English (linked)Muscle changes: We preferentially lose type-2 (power) fibers with age; quads are especially affected. Training can target this. Review.Women & men both lose muscle mass percentage-wise; patterns differ but loss is universal. Same review.Bone density: Women can lose ~2–3%/yr at the spine around menopause; men decline more gradually. CDC data brief.Running & knees: Long-term cohorts show no higher knee OA in runners vs. non-runners (Stanford cohort; systematic review, ~14k people), and even runners with established OA didn’t worsen—and reported less pain. Prospective OA cohort.Strength at any age: Even adults 85+ can add ~10% quad size and ~40% leg strength in 12 weeks; heavy strength work is safe when programmed well. Overview.Power/fast-twitch support: Short (30–120 s) high-intensity efforts and plyometrics can improve type-2 fiber function and neuromuscular drive in older adults. Narrative review.Bones respond to signal: In 80 trials (5,500 postmenopausal women), combined resistance + impact training improved spine and hip BMD regardless of menopause timing or baseline status. Meta-analysis.Recovery with age: Some data show more soreness and temporarily lower strength 24–72h post-lifting in middle-aged vs. young adults—supporting a touch more recovery after hard days. Study.Practical takeawaysLift twice weeklyAdd brief power: 20–30-second hard intervals or controlled mini-hops/step-downs; keep impact tolerable.Build bones: pair resistance work with  impact (jog/jump rope as tolerated). If you have osteopenia/osteoporosis, get your plan cleared first.Recover like it matters: if a session is truly hard, consider one extra easy/recovery day.Audit risk: dial back higher-risk activities that would sideline you for weeks; prevention preserves gains.If this episode helped, please rate the show and share it with a friend. To get my newsletter with practical, evidence-backed steps for living long and well, visit DrBobbyLiveLongandWell.com.
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  • #55 The 5" food rule: safe to eat? Or misguided?
    Send us a textBe honest—have you ever rescued a French fry from the floor? In this bite-size myth episode, I test the famous “5-second rule.” I walk through what actually transfers to your food (fast), when that matters, and why a little microbial exposure isn’t always the villain—while drawing a hard line for high-risk settings and situations.Key Topics & TakeawaysThe verdict meter: The 5-second rule is false—bacteria can transfer in <1 second. In a Rutgers lab study, juicy foods like watermelon picked up the most, gummies the least; tile/steel transferred more than carpet (Applied and Environmental Microbiology / PubMed).Foodborne illness is common: ~48M illnesses/year in the U.S., ~128k hospitalizations, ~3k deaths. Usual suspects include Salmonella, E. coli, Campylobacter, Listeria, and norovirus. Symptoms are typically GI, but severe cases occur—especially in the very young, elderly, pregnant, or immunocompromised (CDC overview).Context matters: Moisture and surface trump “time.” High-moisture foods collect more microbes; visibly dirty or high-traffic floors (think convenience stores) raise risk—regardless of seconds.When to skip the floor food—no debate: If you’re immunocompromised, pregnant, very young/elderly, or you’re in a hospital/clinical setting, don’t eat it. Full stop.Nuance: Are microbes always bad? Early, diverse exposure to benign environmental microbes associates with more resilient immunity. Farm-exposed kids had lower asthma/atopy rates (≈20–40%) versus city peers (NEJM). Greening urban daycare yards (adding soil/plant matter) increased skin/gut microbial diversity and shifted immune markers in a favorable direction (Science Advances). This doesn’t mean “eat off the floor”—it means the bigger story is about exposure diversity and context.My practice: At home, I don’t stress over a quick drop on a clean surface; out in public or medical settings, I pass.Bottom Line Microbes hop on fast; the “rule” doesn’t save you. But danger depends on what fell, where, and who is eating it. Be smart, especially if you or your environment are higher risk.Call to Action What health saying should I myth-test next? Text me your favorites (include your email so I can reply), and please rate the show on Apple/Spotify. Want my newsletter on practical, science-backed longevity? Join me at DrBobbyLiveLongAndWell.com.
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  • #54 What are we to believe? (With Dr. Adam Cifu)
    Send us a textSummary: I unpack why medicine sometimes reverses course—and how you can tell sound evidence from shiny anecdotes—with physician-author Dr. Adam Cifu of the University of Chicago and co-author of Ending Medical Reversal.Key topics & takeawaysWhy medicine “flips”: Plausible theories + observational data → premature guidelines; true answers require randomized trials. Classic examples: menopausal hormone therapy, early peanut avoidance, and stents for stable angina (LEAP trial, COURAGEOpen-minded skepticism: Ask, “What’s the human outcomes evidence?” Cool mechanisms and moving testimonials aren’t proof.Hype outside the clinic: Mitochondria “rechargers,” microbiome panaceas, and biological age tests are intriguing—but not ready for prime time.Nutrition sanity:  For supplement evidence summaries, I like Examine.When AI helps (and when it doesn’t): Tools can orient you to established topics; they’re weaker on breaking studies. Look for linked primary sources.N-of-1 experiments: When evidence is uncertain and the outcome is measurable (sleep, blood pressure, pain), test on yourself—track a baseline, try the change, measure again, and, if possible, stop-start to confirm. Use symptom diaries, validated scales, or wearables.Humility is a signal: Trust sources that sometimes conclude “we don’t know.” I often check Cochrane Reviews for balanced syntheses.About my guest Adam Cifu, MD is a professor of medicine at the University of Chicago, author of 140+ peer-reviewed papers, and co-author of Ending Medical Reversal. He writes at Sensible Medicine.Call to action If this episode helped you think more clearly about health claims, share it with a friend and leave a quick review on Apple or Spotify. For my newsletter on practical, evidence-supported longevity, visit DrBobbyLiveLongAndWell.com.
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  • #53: Ultra-Processed Foods: How Harmful and Why?
    Send us a textI unpack what “ultra-processed” really means, why these foods are so easy to overeat, what the best evidence shows (including metabolic-ward studies), and how I personally navigate them without fear or perfectionism. Key topics & evidence (in plain English):What counts as “ultra-processed”? I walk through the NOVA system—useful, not perfect—and where borderline items (frozen meals, boxed mixes) fit. See an overview of NOVA classifications here. How we got here: post-WWII abundance of refined flour, cheap sugars, oils, and a cultural push for convenience—now ~60% of the U.S. diet comes from UPFs (study). Additives: stabilizers, emulsifiers, preservatives, and colors are generally recognized as safe (GRAS). I explain why, on their own, they’re probably not the main health issue. The bigger problem: UPFs are energy-dense, engineered for bliss (fat/sugar/salt + perfect texture), and easy to eat quickly—driving higher calorie intake.  • Metabolic-ward crossover trial: +~508 kcal/day when participants ate UPFs vs minimally processed (Cell 2019). • Overweight adults in a crossover design: +~814 kcal/day on the UPF week (PubMed). • Another recent crossover RCT reports ~300 kcal/day higher on UPFs (Nature Medicine 2025). What I recommend (and what I do):Prioritize whole foods most of the time; shop the perimeter; cook when you can. Canned tomatoes/beans and frozen fruits/peas are fine helpers. If weight, diabetes, or blood pressure are concerns, be extra cautious with UPFs—they’re designed to be irresistible and calorie-dense. Moderation wins: I enjoy favorites (yes, even boxed mac ’n’ cheese and crunchy peanut butter) without letting them dominate my plate. Takeaways you can use today:Build meals around minimally processed proteins, veggies, fruits, and beans; let convenience items support—not star—in your diet. Watch “calorie-dense + easy to overeat” combos (chips, sweets, fast food). If you have them, portion once, then put the package away. If symptoms or inflammation are puzzling you, try a short UPF-light experiment (2–4 weeks) and see how you feel. If this episode helped, please follow and leave a quick review—and share it with a friend who’s curious about UPFs. For my newsletter and resources, visit drbobbylivelongandwell.com.
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  • #52: We can reduce our cancer risk
    Send us a textCancer is the second leading cause of death, and while it sparks fear for good reason, 40% of cases are preventable. In this episode, I outline six practical, evidence-based steps that can help reduce your risk.We begin by understanding which cancers are most common based on gender—breast, colon, and lung in women; prostate, colon, and lung in men. While some rare cancers (like pancreatic or ovarian) evoke greater fear, the focus here is on the ones we’re more likely to face and can meaningfully act on.Next, I break down risk factors into two categories. Some are unavoidable—your sex, age, or family history. For example, if a close relative had breast or colon cancer, early screening or genetic testing may be warranted. However, only about 5–10% of cancers are directly linked to inherited genetic mutations (American Cancer Society).The more empowering list? Avoidable risk factors—where our actions matter most. Smoking remains the leading modifiable cause of cancer, responsible for about 19% of all cases. Excess weight and obesity account for another 8% and are especially tied to hard-to-treat cancers like pancreatic and ovarian (ScienceDirect) and PubMed). Visceral fat appears more predictive than BMI alone. Alcohol, especially in large quantities, is also linked to liver, GI, and breast cancers.Some risks are cancer-specific. HPV causes nearly all cervical cancers, and melanoma is largely driven by UV exposure. Air pollution, especially particulate matter, may slightly increase lung cancer risk (ASCO Global Oncology).Step three is to act on what you can. Quit smoking, aim for a healthy weight, wear sun protection, and ensure your kids get their routine HPV and Hepatitis B vaccines. Exercise plays a major role too—high activity levels correlate with 10–20% lower risk of several major cancers (JAMA). In colon cancer survivors, regular exercise reduced recurrence by 30% (PubMed).Step four is awareness: don’t ignore new symptoms like unexplained bleeding or lumps. Early detection can be life-saving.Step five is screening. If you're 45 or older, colonoscopy is now recommended. Women should get regular mammograms and PAP smears, and individuals with smoking history may benefit from lung CT scans. For rarer cancers with family history, targeted screenings may apply. I also address why whole-body MRIs and liquid biopsies aren’t ready for routine use.Step six? Don’t put your hope in supplements. Large trials show omega-3s, vitamin D, beta carotene, and vitamin C offer no real protective benefit (NEJM VITAL Study, Meta-analysis on Vitamin C, JNCI on aspirin).Takeaways: You can reduce your cancer risk by modifying lifestyle factors like smoking, weight, and activity. Don’t delay screenings—they catch cancers early when treatment is most effective. And remember: no supplement replaces proven preventive strategies.Visit drbobbylivelongandwell.com for more evidence-based tools, and listen to the full episode for actionable steps to help you live long and well.
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About Live Long and Well with Dr. Bobby

Let's explore how you can Live Long and Well with six evidence based pillars: exercise, good sleep, proper nutrition, mind-body activities, exposure to heat/cold, and social relationships. I am a physician scientist, Ironman Triathlete, and have a passion for helping others achieve their best self.
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