Fat Science

• More Mailbag

  On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright open the mailbag and answer questions from listeners all over the world.Dr. Cooper provides expert insights into complex questions about metabolic health, covering topics including metabolic dysfunction, the effects of chemotherapy on metabolism, a discussion of GLP-1s and those trying to get pregnant and the role of iodine in the diet. Engaging and informative, this episode also arms you with the vocabulary and understanding needed to discuss metabolism with your healthcare provider.Key Takeaways: Metabolic medications like GLP-1s are not just for weight loss; they target the metabolic system, improving fertility and metabolic health. The jury is still out as to whether taking GLP-1s are safe for those trying to become pregnant, but management is possible knowing the half-life of the various GLP-1 drugs. Chemotherapy can impact metabolism; a comprehensive metabolic assessment post-treatment is essential for recovery. Iodine is crucial for thyroid function, and deficiencies may arise from using non-iodized salts; checking iodine levels can guide supplementation. Managing mindset and mechanical eating is essential when using metabolic medications to avoid calorie-counting traps.Personal Stories & Practical Advice: Andrea shares her journey of freeing herself from calorie counting and embracing a healthier mindset. Listeners' questions reflect global engagement and common challenges faced in managing metabolic health.Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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• The Metabolic Links to PCOS

  On this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the intricate metabolic ties to Polycystic Ovarian Syndrome (PCOS). Dr. Cooper provides expert insight into how understanding these links can transform what seems like a permanent condition into a reversible one. “ I feel like there's so much despair around PCOS when it actually doesn't have to be a long-term condition,” says Dr. Cooper. “I know some of that desperation comes from the infertility piece of it… so it's really important to calm down the (metabolic) dysfunction to be successful in fertility.”Key Takeaways: PCOS is often misunderstood as solely an ovarian issue, but it is deeply rooted in neuroendocrine and metabolic imbalances. Diagnosing PCOS involves analyzing menstrual irregularities, androgen levels, and related physical symptoms like hirsutism and acne. Traditional treatments include metformin and spironolactone, but focusing on overall metabolic health can lead to reversal of PCOS symptoms. The importance of comprehensive metabolic health, including regular fueling, sleep quality, and potentially targeting specific metabolic pathways, is emphasized. Misguided advice to lose weight often exacerbates PCOS; instead, enhancing metabolic signals offers a sustainable solution.Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  36:08
• Letting Go of Calories-In, Calories-Out

  On this episode of Fat Science, it’s time to let go of the old paradigm “calories in, calories out.” Join hosts Dr. Emily Cooper, Andrea Taylor and Mark Wright as they kick CICO to the curb. The idea that a person’s weight is determined only by the ratio of calories consumed and calories burned is an over-simplification and often not true, especially for people with metabolic dysfunction. Dr. Cooper reveals the real key to weight management is not calorie counting but understanding metabolic function influenced by the  neuroendocrine system. Through personal stories and insights, they explore why diets don’t work and how acknowledging the complexity of metabolism can lead to better health.Key Takeaways: Caloric intake does not have a static burn rate; it's controlled by dynamic neuroendocrine signals. Metabolic adaptations occur with calorie restriction, reducing metabolic rate, making weight loss unsustainable over the long term. The science holds answers to metabolic dysfunction, revealed by metabolic testing and hormone imbalance recognition. Education and communication can challenge and change the stigma and bias around weight, leading to a more informed society.Personal Stories & Practical Advice: Andrea shares her journey about ignoring diets and focusing on metabolic health for long-term benefits. Dr. Cooper recounts her challenges in communicating her findings in a positive way, leading to greater acceptance and understanding among patients, healthcare providers and the general public.Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram.Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice.If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected] Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  37:56
• Straight Talk on Compounded Drugs

  In this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore the world of compounded drugs. These are medications prepared by pharmacists to meet specific needs of patients when commercially-available products are not an option. Changes in dose, accommodating patients with allergies or sensitivities and drug shortages are some of the reasons the FDA allows compounded drugs to be made and sold. Key Takeaways: Compounded drugs are manufactured by pharmacies to offer alternatives to brand medications but lack FDA approval for safety and efficacy. Loopholes in drug shortage laws have allowed a surge in compounded GLP1s, though these shortages are now being resolved. Concerns arise over the quality, dosing, and potential immune reactions that compounded drugs might provoke, especially when not FDA-tested. Choosing FDA-approved drugs ensures strict regulation, accountability and proper testing to safeguard health. Consumers face aggressive marketing tactics aiming to sell compounded drugs at lower prices without guarantees of safety or effectiveness. Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram. Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice. If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected]. Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  36:08
• Cravings: Culprit or Symptom.

  n this episode of Fat Science, Dr. Emily Cooper, Andrea Taylor and Mark Wright explore cravings and the role they play in metabolic dysfunction. If you watch some drug company commercials these days, you’d think cravings are the culprit for obesity. In reality, they are just a symptom of a deeper metabolic problem.  This episode of Fat Science uncovers why this oversimplification is not just misleading but harmful to those struggling with metabolic dysfunction.  Join us as we explore the science behind cravings, debunk common myths and highlight the importance of understanding your metabolic health. Key Takeaways: Not Just an Overeating Problem: Learn why targeting cravings alone is not the answer to managing weight and metabolic health. Metabolic Dysfunction Explained: Discover how metabolic dysfunction manifests in various forms, such as irregular appetite signals, and why addressing the root cause is crucial for effective treatment. The Role of Medications: Dr. Cooper breaks down commonly-prescribed medications like Contrave, Qsymia, and Saxenda—explaining their true function in strengthening metabolic pathways rather than merely suppressing cravings. Misleading Advertising: Understand the detrimental effects of current advertising campaigns that focus on willpower and cravings and how they perpetuate weight stigma and misinformation.   Resources: Connect with Dr. Emily Cooper on LinkedIn. Connect with Mark Wright on LinkedIn. Connect with Andrea Taylor on Instagram. Fat Science is a podcast on a mission to explain where our fat really comes from and why it won’t go and stay away. We are committed to creating a world where people are empowered with accurate information about metabolism and recognize that fat isn’t a failure. This podcast is for informational purposes only and is not intended to replace professional medical advice. If you have a question for Dr. Cooper, a show idea, feedback, or just want to connect, email us at [email protected]. Fat Science is supported by the non-profit Diabesity Institute which is on a mission to increase access to effective, science-based medical care for those suffering from or at risk for diabesity. https://diabesityresearchfoundation.org/

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  39:11

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