This episode provides a comprehensive review of supplementation in cycling performance, based on recent research from the UCI sports nutrition project. Cam Nicholls and RCA coach Ben Treble discuss food-first approaches, effective supplements like caffeine, creatine, beta alanine, nitrates, and more, emphasizing evidence-based choices for cyclists.
Research:Â https://pmc.ncbi.nlm.nih.gov/articles/PMC12912213/Â
AIS: https://www.ausport.gov.au/ais/nutrition/supplementsÂ
Stanndards: https://stannards.com.au/Â (podast sponsor)Â
Key Takeaways Prioritize whole foods for macro and micronutrients before supplements.
Use the AIS framework to identify high-efficacy supplements (Group A).
Caffeine can improve performance by 2-5% and should be dosed 3-6 mg/kg about an hour before effort.
Sodium bicarbonate (bicarb) and beta alanine buffer muscle acidity, effective for high-intensity efforts.
Nitrates from beetroot juice reduce oxygen cost of submaximal exercise, beneficial in hot conditions.
Hyperhydration with glycerol or sodium can improve thermal regulation in long endurance events.
Avoid unverified supplements; choose those with third-party testing and certification.
Supplements like ketones currently show mixed results and are not recommended for performance enhancement.
Chapters
00:00 Introduction to the episode and guest
00:26 The context of cycling performance and supplement discussion
01:28 Overview of the UCI sports nutrition project and key authors
02:53 Navigating supplement marketing noise and the food-first approach
03:43 The importance of macro and micronutrient intake from whole foods
04:49 Training on 100 grams of carbs per hour and its benefits
05:46 Using the AIS supplement framework to guide supplement choices
07:35 Key supplements in Group A: caffeine, creatine, bicarbonate, beta alanine, nitrates, hyperhydration, exogenous ketones
08:23 Caffeine: dosing, effects, and practical tips
12:24 Sodium bicarbonate: buffering capacity and application in high-intensity efforts
16:40 Beta alanine: muscle carnosine loading and effects
28:59 Nitrates from beetroot juice: reducing oxygen cost of exercise
33:27 Hyperhydration with glycerol and sodium: benefits for endurance in hot conditions
35:06 Exogenous ketones: current evidence and performance implications
39:07 Summary and practical advice on supplement strategy
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Transcript:
Cam Nicholls (00:01.804)
Welcome to the RCA podcast designed for recreational and amateur road cyclists with a focus on performance. We dive into cycling training, nutrition, strength training for cyclists and even bike fitting tips all designed to help you train smarter, ride faster and hopefully tear your mates legs off. So without further ado, let's dive into today's episode.
Welcome back to the RCA podcast where today I'm joined by RCA coach and science geek Ben Treble and we're in a hotel room in Sydney. We're here supporting the boys at the RCA Bikes Online boys at the Pro Velo. Ben, what are you doing?
Ben Treble (00:40.53)
I'm filling in some big shoes from Ryan, our team manager in DS and playing the DS role while Ryan's on the pedals.
Cam Nicholls (00:47.458)
Nice. And I'm here to try and make some content. So we thought we'd use the opportunity to get together for a couple of podcasts. And today we're to talk about a comprehensive review on supplementation in cycling performance that was released recently, February, 2026. And this was a paper that Ben brought to my attention, I think via Instagram story, I saw you share it. And I was like, that's pretty interesting. And it kind of sort of validates a lot of supplements that are
you know, we know that work, but also highlights an area that I think a lot of people tend to forget about. So Ben, you've looked at the paper in detail. What do you make of it?
Ben Treble (01:28.054)
I love it. My caveat is, I'm, I'm, very biased on this one. So firstly, it's one paper out of, think there's 15 papers that are being slowly released. So they're not all released yet. And it's part of a much bigger project where the UCI commissioned essentially the world experts in all their different topics related to nutrition. And it's called the UCI sports nutrition project. And there are many, many papers on different topics about cycling. So.
Yeah. One of the papers is the sports nutrition paper. It's on the use of sport foods and supplements to improve performance in cycling. One of the key authors is Jamie Whitfield, who was a supervisor of mine when I did placement at a lab in Melbourne. cool. I hold him in very high respect. He's, he's much smarter than myself. I would think of him more of a biochemist, sports scientist actually, but he's brilliant. You know, of course, Burke was a big part of that paper. Who's probably one of the top.
I would argue the number one sports nutritionist in the world. contribution to both research and practice within Australia in a global context is phenomenal. So very good paper, highly recommend. We will link it that paper, I'm sure, for people to have a look in the potty. So what are we doing about this paper? Well, they just really want to dig into, as you all know, you probably all get bombarded on media from a hundred million companies about take this supplement, take this, take oxygenated water. There's so much noise.
Out there, it's difficult for people to navigate what actually works.
Cam Nicholls (02:57.422)
I'm in an ad actually promoting AgeMade. guess a lot of people would have seen that ad.
Ben Treble (03:02.319)
I have received this head many times. I'm in my mid thirties and I've received the age mate.
Cam Nicholls (03:07.926)
Yeah, sorry about that. It's a good supplement though. I did my blasts, my bloods it worked for me. So, okay. I stand by that one. Okay.
Ben Treble (03:14.222)
Cook me up and I'll try it. Back on topic. I'm not talking about age made in my list today, just for the reference. Sorry for your plug. What this paper does is it tries to really break down what's important and what's not for people. And I think the first point that we really want to get across to the audience today is you should really try to have a food first approach, which means try to get your macros and micronutrients from, you know, like
natural whole foods first.
Cam Nicholls (03:45.582)
Feats any supplement, hands down, every day of the
Ben Treble (03:48.152)
Every time the bio availability of all the important things you really need from whole foods is just so much more important than worrying about spending too much money on supplements. Yep. Good. We can agree on the first point. Did everybody hear that? Yeah. Food first approach. Yeah.
Cam Nicholls (04:03.918)
The last training block I did for Grafton to Indoveral, which is a big bike race here in Australia last year, was the first time I properly did train on 100 grams of carbs per hour. And I know that's not necessarily whole food, that's a lot of sugar, but it's part of the macro nutrient approach. And I'd never trained so well in my entire life and I'd never recovered so well as well. Like for example, a five hour ride, hard, on a Saturday.
used to leave me like in pieces in the afternoon, fatigued, tired, grumpy, but training at 100 grams per hour, I was recovering better, I was sleeping better, I wasn't grumpy, and then the adaptation was better, and then you can take that adaptation to the next training session. So just this is one small example of getting my macronutrients right for training, made such a big difference.
Ben Treble (04:49.198)
Yeah, I can think of a new RCA athlete of mine and we've spent, you know, the first few weeks not even talking about power or doing fancy VO2 intervals. The entire focus has been how do we get you eating more food on the bike? And that's what's making the difference. Trying to slowly build up the ability and experimenting with different foods. Is it bars, gels, liquids? What works for her and her stomach?
and what's going to help her get more fuel in to do the effort. There's no point doing the efforts until we know we can get the right fuel in. So yeah, big point on that, but we're not here to talk about that right now. We're here to talk about the juicy stuff, which is supplements. So, the first part of this conversation is what is this paper reference and what do I tell all my athletes when we first talk about food and supplements? And that's probably one of the best resources out there. Firstly, because it's free.
You know, I would argue, you know, they don't have any bias because they're not leaning towards any certain company. It's published from the Australian Institute of Sport. So the AIS has a supplement framework and there's an entire team of sports scientists and researchers who are digging through the research, doing their own research. And they publish a framework where they're grading certain supplements based on their efficacy. Like does the supplement do what it's supposed to do?
If they claim it has a certain performance benefit, does it actually do this? How strong is the body of research behind it that then supports that? How safe is it? And what are the downsides or the risks from an antidoping perspective or a health risk, health hazards? And they factor all that in and then they grade it. Is it an A group, which would be like the highest level? You know, this is the group that you can pretty confidently say it will do what it says it does. It's safe to take and.
That's where your focus should be on this group, group A. Group B would be there's some evidence for it. It's interesting and we're keeping an eye on it. And you'll see supplements move between these groups as the research bodies grow. So an interesting one would be, you know, for example, nitrates, beetroot, that used to be a B group supplement. And as the research has grown to support it more,
Ben Treble (07:06.126)
It's been lifted to a group A. Supplements. That's just, they're regularly updating this framework. So I tell people to keep an eye on it. And then you've got group C and D, which are essentially supplements you should ignore in my eyes. I would just check the list because maybe you want to try something that you've got a marketing ad for. And if you see it in these groups, maybe it's a good sign to just keep an eye on it, but not touch it yet. So today we're going to focus on, we're going to talk about quite a few different supplements that are within the group A category. So I'm just going to...
wrap them off real quick. The ones that we care about. Caffeine, creatine, bicarb, that includes sodium citrate, beta alanine, nitrates, hyperhydration, that's through glycerol, and then exogenous ketones are added to the list. That is a B group supplement. I've just put it there because I know it's a hot top.
Cam Nicholls (07:54.866)
Interesting and it's relatively new in comparison to the other ones as well. So there's a fair chance it might end up at the top of the tree, would you say? okay, interesting, I already saw that.
Ben Treble (08:02.67)
My view is it won't. Well, there's multiple papers now across different sports that show it actually has a detrimental effect on endurance performance. Interesting. Yeah.
Cam Nicholls (08:17.102)
Okay, alright, maybe that's a rabbit hole for another day. We'll leave it at that. I like that, we're on the caffeine right now.
Ben Treble (08:23.672)
I'm on number three for the day already and let's, it's just after nine and we've got races starting at just before lunch. So hot topic. Let's kick it off on caffeine, Ken. I don't think we need to a lot of time on this, but caffeine does what it says it does. know, caffeine at the end of the day, the primary mechanism it's via the central nervous system. It reduces your perceived effort and fatigue whilst improving focusing and pacing strategies.
What I've done for this conversation is I've had a look at what was put out in the UCI paper and I've gone and, you know, cross-checked it with what's in the AIS framework from a dosing perspective. Just as a heads up to listeners, the UCI paper is, from my eyes, is fairly focused on acute dosing. Whereas if you go into the AIS framework, they often provide acute and chronic dosing strategies for these supplements. So I would actually tell people, if you see something in the UCI paper you're interested in,
go check it out in the AIS framework where you can get, you know, they have these great PDF infographics on each supplement with dosing strategies and guides and things to watch out for. So I'm just
Cam Nicholls (09:31.406)
Just conscious a lot of our listeners are European, USA, Canada. So the AIS, which is the Australian Institute of Sport, would you say that their guidelines here would be similar to that in the US and Canada and Europe? Do they tend to be aligned or have you seen discrepancies in the past?
Ben Treble (09:49.8)
Not that I've done a lot of digging, but of all of my American and my European athletes I work with, none of them have ever seen anything like the AIS framework before. Okay. And they don't know of anything in their home countries. Okay. With that available. So whether they hold that information internally, because they think of it as IP or a competitive advantage, would be my guess that they probably do. And they might provide it to certain athletes and teams or performance staff.
But it's probably internal only, they don't publicly share it. Okay. So then, yeah, we don't know if it's the same or not. Okay.
Cam Nicholls (10:23.918)
guess AIS1 though can be trusted because we all know Australians are good at sport. We know what we're doing so it's a good reference point.
Ben Treble (10:31.502)
Yeah. I think we're an over performer in the winter sports as well. There you go. For the size and not being a winter country. Off topic. Back to caffeine. We'll go through this one quick. Cause I think it's, everyone knows caffeine does do what it does. It works well. Main things to be aware of the dose is probably anywhere from three to six milligrams per kilogram of body mass. Ideally you take it around an hour before your exercise, or if you have a longer event, you can stagger it through the event. So you don't have a massive dose.
AIS recommends a max of three milligrams. Caffeine used to be a banned substance on the anti-doping water list. It is no longer a banned substance, but it's just, you you need to keep an on that. This gets updated every year. So who knows if in two years they'd ban it again. Unlikely, but yeah. Other than that, you just probably need to be aware of if you take too much excessive use gives you anxiety, jitters and sleep disruptions, which most people are aware of. yeah.
Cam Nicholls (11:24.194)
Sounds like May every day.
Ben Treble (11:25.87)
What I thought was cool, I've never actually looked at it, but they do reference in the paper, you know, the expected performance improvement is from two to 5%. And that's been proven across multiple sports and distances. So caffeine guys, if you're not taking it, second point on caffeine I would have, I typically get my athletes to switch from coffee in terms of racing to, we call it anodos here in Australia, which would be caffeine pills. So you know exactly how much you're taking for your race if you want to take.
50 milligrams at half an hour before the line and then halfway through the race, you take the other half, whatever you want your dosing to be. Typically large people take a little bit more, but yeah, I would recommend that you switch over to pills because you know, a standard cappuccino, the range and how much caffeine you get from that varies massively. So you don't actually know how much you're taking. True. Let's move on to probably one of the supplements that Kem is a big fan of. And I'm a big fan of as well.
setting by car. Yeah.
Cam Nicholls (12:26.67)
buffering the lactate. Yeah. Just grind at threshold all day long.
Ben Treble (12:31.148)
Yeah. Yeah. So this one's a good one. Sodium bicarb. Cause one it's cheap. It's easily available and accessible. Everyone's supermarket has this within the same group is sodium citrate. They're essentially the same thing for the point of this conversation. What does it do? It's, it improves your buffering capacity of the hydrogen ions. So it slows down the rate of acidity and the shifting pH as the intensity goes up. So at the end of the day, what is it doing? It delays your exercise induced.
acidosis during high intensity efforts. The research shows that the performance benefits are in that like one up to 60 minute efforts, but the research is a lot less supportive the longer you go outside of that range. So when we talk about road racing or a Gran Fondo event where it's anywhere from two to four or five hours, the efficacy for using bicarb gets a lot lower.
Interesting. So would I use it for a road race? Probably not, personally. Would I use it for a crit race or if you do any track cycling or sprint work, would I use it in training for a sprint session? Yes. So is it worth using in training, even if it's not going to be used in your race? Potentially. Yeah.
Cam Nicholls (13:46.54)
I think there's a bit of a gash prone issues that people can experience with this one as well. They need to be aware of. So like slowly dose it in kind of thing.
Ben Treble (13:54.638)
Yeah. So from a dosing and a risks perspective, the biggest risk on bicarb is gastro issues. I mean, at the end of the day, it's almost like the more you can take the better. But at some point you get significant gastro issues, which will stop you performing. So there's a little bit of trial and error for individuals and you can progressively, you know, train yourself to take more to reduce those gut issues. Another tactic you can do is some companies will sell bicarb in pills.
even better and harder to find is they sell it in a slow release capsule. Yeah. Okay. So if you take bicarb, you know, just from the supermarket in a powder and you mix it in water or however you want to take it, it tastes terrible. If you can put it into a slow release capsule, it's probably going to help with the gastro issues. The loading protocol is typically one to three hours pre-exercise, two to 300 milligrams per kilogram of body mass. The chronic dose is big.
which would be 500 milligrams per kilogram for five days. Wow. So big chronic loading dose. They also recommend that if you do that acute dose that you can either take it with fluids or take it with a carb meal. And that will help with the gastro issues. Yeah.
Cam Nicholls (15:10.38)
I know what got me onto it. I was at the Tour de France behind the scenes, 2024, Visma Leesa Bike and Nathan Van Hoede, something like that, who I can't pronounce his surname. He's a very good Belgian rider. He actually had a heart attack the previous year. So he was racing with Visma. He was just in the car. But he was telling me that the number one supplement that the team was using at the time that everyone loved was the Morton gel mix by carb. And I was like,
Pro athletes are saying that it's the best supplement that they're using at the time. I need to get onto this. And think there was a famous scene of a, I think it's, don't know the writer's name. He was the Canadian world champ though, in a road race, actually eating bicarb because their races are like five, six hours, like halfway through the race, having a bicarb gel mix and eating it out of a tub during a race. obviously it's held in high regard, that elite level bicarb.
Ben Treble (16:05.698)
Yep. I mean, it works. Right. And at of the day, one of the biggest things that often holds people back during high intensity racing is, you know, their ability to clear lactate, right. And reduce acidosis. The longer you can hold that back, it's going to give you a performance gain. So cheap, accessible, safe. Just have to do a bit of trial and error for gastro issues and with your loading protocol. yeah, sodium bicarb is a really good one to jump on if you've never tried it.
The other one that has a, it's a very similar outcome via a different mechanism is beta alanine. I think you tried it.
Cam Nicholls (16:40.194)
I use it for years. Yeah, I like that one as well. I love the little tingling sensation you get on your neck when you have it, which is so odd. But it's the only one that as soon as you take it, there's like some not within seconds, but like within five minutes, you get a little bit of a skin tingle, which is weird.
Ben Treble (16:56.43)
Yeah, it's a funny one. So what is beta alanine? At the end of the day, what it's doing is it tries to overload your muscle carnosine levels. And what that does is it, again, it improves the buffering of the hydrogen ions. So it holds back the acidosis. What is it good for? It's good for one to 10 minute max efforts. There's some research showing that maybe it has a better effect for longer durations than bicarb. Interesting. So this is a supplement that...
I used for Grafton to Inveral. The downside to beta alanine compared to bicarb is from the research, the loading protocol to take it, there's no acute protocol because you have to flood the muscle carnivore levels and this takes weeks with very high doses. So it's very difficult because the body is very good at self-regulating these kinds of things. And so it's very difficult to get it to actually increase muscle carnivore through exogenous supplementation.
So that's why the loading protocol is it's around four to six grams per day for at least four weeks. Four weeks. So I remember taking, I split that dose into four doses per day. And that was, I think it was four pills every dose. I had 12 pills to take every day and I did it for six weeks prior to my event. they say once you've done that four week loading, they say the maintenance dose is only 1.2 grams per day.
So that's new since I did it. They're saying you could sort of get away with a four to six week loading protocol. And then there's a maintenance dose once you're in that saturation phase, which is only 1.2 grams per day. As you already brought up, the main downside, there's very little evidence of gastro issues, which is why some people lean towards beta alanine over bicarb. So for those of you who've tried bicarb and get really bad gastro issues, maybe give beta alanine a go. But again, yeah, this side effect is
You get this tingling sort of pins and needles and people get it either all over the body or in different places. I used to get it in my cheeks and my fingertips. I didn't get it in the toes. Some people get it in the toes. You got it in your neck like, it's all, it's quite constant. And if you do this for six weeks, some people can't handle the tingles for six weeks. So maybe before you start this one, be prepared. You have to be ready to have a bit of an unusual sensation for six weeks. I swear by it.
Ben Treble (19:23.296)
I put down a big part of my performance for back when I was racing at Grafton down to beta alanine.
Cam Nicholls (19:30.594)
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to the
starts to come in and your power drops by 10%. I could probably go another half an hour or an hour when I was on better aniline. And that was really, really noticeable.
Ben Treble (21:33.55)
Yeah, I think it makes a big difference. yeah, two, there's two supplements that both work on reducing or buffering the hydrogen ions. So reducing the acidosis or prolonging it, but they're through different mechanisms. There's very little research looking at both of them together. So what happens if you combine them? So I actually think there's a potential big gain to be doing both. Yeah. So it's not well researched, but I'm for certain races. If you have like a hard start race.
Cam Nicholls (21:54.659)
Interesting.
Ben Treble (22:01.624)
I don't see why he couldn't do bike carb to sort of get through the first hour, which is usually a very key part of a race versus beta Alanin. Maybe for our listeners, if you think, for those of you who are in Australia doing a Gran Fondo Worlds at Lawn, where you had a climb, like I think it was in the first kilometre, you go up this like 15, 20 minute berg straight out the gate. Like that's where your bike carb is going to be helpful. But then in the backend of the race, like two hours later, the bike carb's probably not doing anything.
Beta alanine if your muscle carnivine levels saturated that's going to help you buffer the acidosis in the second half.
Cam Nicholls (22:37.518)
Just phase them in though, don't be double dropping both of them. You'll be running to the toilet and tingling at the same time.
Ben Treble (22:43.732)
Yeah, and this was, I mean, for any of my athletes who try this and for the listeners, I trial this ideally, like at least six months prior to an event where they're thinking of using it for the first time. So, we go through a phase where we really test this out and we test it out with a race that they don't necessarily care about, a race we're using for training. And we really test out one, a protocol, and then we know for the race we care about.
Okay. Did it work? Did we have gastro issues? Do we want to tweak the protocol? Did it just not work? Cause you always get some non-responders. Was it worth it? Yes or no. You can make that decision. Don't try this first time at a race you care about. No way. So two very cool supplements. I think, you know, and both of those are in the A group in the AIS framework. So yeah, we'll jump on the next one. Let's talk about creating. Okay. Group A supplement. you on the creating?
Cam Nicholls (23:36.93)
Yeah, I actually take it with my age mate. Splendid, do you? Yeah, so you scoop your age mate into water and then I scoop my creatine, shake it up and I drink it before I have my morning coffee. Then I run to the toilet. Yeah, so I'm on the... because there's a lot of research now that creatine isn't just good for sports performance, it's also good for just general health and wellbeing.
Ben Treble (23:52.684)
Is that a single or a double shot?
Ben Treble (24:03.758)
So jumping on the sport performance side, the paper, you know, essentially what is it supposed to do? It improves high intensity sprint performance and repeated efforts. here we're talking about fatigue resistance. And in my eyes, fatigue resistance is how many times can you repeat your like best sprint power before it drops off a cliff?
Cam Nicholls (24:21.856)
Yeah, it's like watching yesterday's Pro Velo race surround that crypt track. Yeah. Just neurological, you know, if it's neuromuscular, I should say.
Ben Treble (24:29.474)
second laps with a boot up a small hill every 30 seconds for like 60 laps. How many times can you do your best sprint if it's let's say 600 Watts? Can you do that 60 times every 30 seconds for an hour? Yeah. So that's what the paper's talking about. Obviously there's a lot of other benefits to creatine that it's not going into. How does it do that? It increases your intramuscular phosphocreatine stores. And what this does is enhance ATP, which is energy currency.
resynthesis during maximal efforts. What's the loading protocol? It's quite big. It's around 20 grams a day for five to seven days. One of the risks or downside is you do initially get a water retention weight increase. So that's typically from 500 grams up to a kilo. That's in the muscle. Yeah. So as a result of having this increased creatine levels in the muscle, those creatine, you get more water molecules bonding to them.
Cam Nicholls (25:16.514)
muscles, yeah?
Ben Treble (25:25.966)
So just stores more water in the muscle than normal and water weighs. So yeah, your weight goes up as a result. There's some evidence that says once you go through a period, if you continually have a very high level of creating stores, your body will normalize and the water levels will drop back down. But particularly in that first week or two, like, yeah, don't be surprised if your body weight goes up. So if you have a very, very, you know, what's a big kilogram focused event, don't do this five days before probably, if you care about your weight.
The other loading dose you could do is so around five grams, four times a day for five days, or you can do three to five grams for 20 days. So you could do a more chronic dose. And then once you've done that loading protocol, the maintenance dose is three to five grams daily. And once you stop, it takes about four weeks and your body will return back to normal baseline levels. So it has a pretty long, I would say a pretty long efficacy period. Hmm. Good. Yeah. I think it's a simple one again.
Relatively cheap, not as cheap as bike up, pretty accessible. We can buy it in a supermarkets in Australia. You don't need the fancy stuff. I feel like I've seen some marketing branding for like.
Cam Nicholls (26:33.198)
Don't worry, I'm buying the fancy stuff. I've been sucking. Yeah, the pharmaceutical grade, you know.
Ben Treble (26:35.66)
Yeah
Don't do what chem's doing. The only thing that's worth spending money on is making sure you get creating that's, um, you know, like has to test it in Australia or different countries around the world. have supplements that are, you know, tested by third-party labs to make sure there's no contaminants. So for those of you who race in grand Fondo events, any event that falls under UCI regulations or rules, which includes most grand fondos. I know we have a lot of those writers in our listening group. actually fall under the anti-doping rules. So.
Yeah. Highly recommend that you make sure any of these supplements you take are either has to certified or sport integrity tested. They're the two big testing labels that you'll see on, on the brand. The reason for that is the large majority of doping infractions are from contaminated supplements. So they're not people doping on purpose. For example, they've gone and taken some supplement that wasn't tested and they get contaminated because they're made in a warehouse in the same warehouse often where
they're brewing up, you know, pre-workout extreme mix that accidentally got a bit of meth in it. Yeah. Or speed or something. And literally it only takes a minuscule amount of that that was left in the batch tub to go into your mix, into your system. And then it comes up as a positive result in a doping test. Okay. There we go. Kradian, do you want to say anything else on it?
Cam Nicholls (28:01.358)
I think creatine to me is almost becoming as elevated as caffeine, I feel. Like it's really, it's been around so long now. It's so well researched. Everyone knows about it. Yeah, I just take it daily. It's part of my repertoire, whether I'm training or not.
Ben Treble (28:15.981)
Awesome. Yeah, to be fair, I take it. I think it's probably been a lot more common in the gym goers prior to the endurance bros.
Cam Nicholls (28:23.968)
I'm a bit of a gym bro though, so I can gym doing my beach weights and getting the water retention in the bicep
Ben Treble (28:30.366)
Kam's upper body looks as big as his legs now guys. All righty. Let's everybody go take your creatine. So next stack in the A group supplements, they call it dietary inorganic nitrates. What's that fancy for? Beetroot juice. People have probably seen like people doing these nitrate shots, drinking purple juice after races. That could also potentially just be cherry tart, which is a different supplement, but yeah, beetroot juice.
and have you taken it? Yeah.
Cam Nicholls (29:01.306)
I remember it, but I probably didn't do it. I'm assuming there's a loading protocol. There used to be these little, and I think you still get them, the Beat It, which is like a beetroot concentrate. So I used to take when I was racing down in Caulfield, Carnegie, Glenvale on a Sunday, I'd have one of those. Never really knew if it did anything. I think when you're racing on the limit for an hour, you kind of don't know if anything's doing anything down there. yeah, so I've taken it, but not really. Unlike...
you know, other supplements where there's a noticeable effect, like betalain I've noticed, bicarb I've noticed, never really noticed anything personally with.
Ben Treble (29:39.512)
Beats. So Beats is a interesting one because it was a B group supplement and it's moved up to the A level group because the evidence has got stronger and stronger on it. What's it supposed to do? It's supposed to reduce the oxygen cost of submaximal exercise. What does that mean? When you push the pedals and you push watts, you've got to produce that energy somehow. The effect typically you would say like for one watt you need 12 and a half.
Some people might say 13, it's typically 12 and a half millilitres of oxygen. Push that one watt. So what this does is it reduces the amount of oxygen required to push that one watt. How the heck does, when I heard that, was like, how the holy heck does beetroot juice, you can't reduce the amount of oxygen it takes to push one watt. What? That's ridiculous. This stumped researchers for a long time because we kept finding the same result. You get people.
On a metabolic cart, we have gas exchange and we can measure the amount of oxygen in carbon dioxide out. And you have two groups. It could be a blinded study where they think they're taking the placebo or the beetroot. And every time the group who had the beetroot, it took less oxygen to push same Watts. Okay. The math is not adding up. No. The mechanism was quite complex. I'm not going to pretend I know a ridiculous amount about it, but in brief.
It came down to talk production at a muscular level and ultimately reduced, you know, the way we produce, you've got velocity times talk to produce power and the amount of talk that your muscles needed got reduced to produce the same Twitch response. And that's what the nitrates were doing. So reduced this, this level of talk required for the same Twitch response, ergo then less oxygen for same power output. it works. The research is consistent.
What do we need to do? You can do an acute dose and that's six millimole of nitrate. I think it's the equivalent of around two of those beta shots, two to three hours prior.
Cam Nicholls (31:42.68)
I wasn't having two shots. I was just having the one shot probably an hour before.
Ben Treble (31:46.53)
So I would smash two shots like two, three hours when you have that last big carb meal before an event. Okay. Yep. I would be doing that. The chronic dose, three to 15 days duration and taking around 350 to 600 milligrams per day as a minimum. And then three days prior to the event, you do three to 600 milligrams and then you can do two to three days before the event. You can even ramp it up again and do just those six millimole shots.
Yeah. So it's pretty big dosage, but research is good. would be doing it. That is nitrate shots are pretty expensive though. So unless you're sponsored by baited or you have a lot of funding. Roots. Yeah. This is where the AIS framework is really good. Cause they talk about the equivalence and it's, it's a lot like, you know, for one baited shot, it was like two or three entire beetroots. That's. Yeah. I don't like beetroots that much. know, or like 500 millilitres of beetroot juice for one shot.
Cam Nicholls (32:27.81)
What if you just ate a lot of beetroot?
Cam Nicholls (32:39.008)
Yeah, no thanks.
Cam Nicholls (32:46.222)
That's when you go to the toilet and you think you're going to the toilet, blood's coming out.
Ben Treble (32:49.966)
Yeah, the Beat It shots are probably the go, they're just a bit pricey.
Cam Nicholls (32:54.23)
Okay, cool. Yeah. How many more on the list? One more?
Ben Treble (32:57.826)
Yeah, there's two more, but we're just going to touch on hyperhydration quickly. This one got me because I hadn't really thought about it that much until I read about it. It does sit as a group A supplement in the AIS framework and it was in the UCI paper. So they call it hyperhydration, but it was via the use of glycerol with your fluids or sodium. So what you're trying to do is increase the total body water and plasma volume in your blood.
offset the sweat loss during prolonged exercise. So it's good. This one is good for the long endurance events or hot conditions, less useful for your short high intensity sort of think track, crit racing. It's improving your thermal regulation and performance by two to 5%.
Cam Nicholls (33:44.258)
Wow, this is a good one for I live in the sunshine ghost where it's quite hot and humid doing these four or five hour rides where I'm cooked at the end. So that's where this sits quite nicely or a big long hot road race. Fondo event, big long Fondo event. Peaks challenge is happening today. Those guys should be doing this.
Ben Treble (34:01.304)
Big time. this kangaroo is on the golf course. Sorry. I'm easily distracted guys.
Cam Nicholls (34:06.382)
We have a lovely view from this hotel room by the way.
Ben Treble (34:09.101)
You have gone all out. The glycerol loading is one to one and a half grams per kilogram of body mass with fluids, or you could do that with sodium. So you could do sodium one to one and a half grams per kilogram. And you just do it pre-exercise. The risk is some people do get GI issues. So you probably want to experiment with this one in training first to find out what works for you. Some people get a body mass increase. I mean, obviously if you drink a liter of fluid.
your weight's going to go up, sorry. So maybe just keep that in mind. But other than that, it's a very simple one. The performance benefit is measurable. It's cheap and accessible. So, yeah, have a read of that one, guys. I would definitely check that one out. That would be high on my list.
Cam Nicholls (34:53.535)
Okay, good. And what's the last one?
Ben Treble (34:55.658)
Last one, caveat, this is a B group. So there's mixed scientific support. It's an emerging supplements. It's probably been a hot topic. I feel like it's not that new anymore, but ketones. Yeah. Exogenous ketones went nuts a few years ago until some of the research started coming out. You know, the first papers that came out were all sponsored by, you know, the companies themselves that were selling these supplements. So in my eyes, I just don't even almost bother reading the paper. just write it off.
Cam Nicholls (35:06.732)
three years ago it was going nuts.
Ben Treble (35:23.03)
And once some actual third-party labs started looking into it, you know, the results either became so mixed that you had to really question it until they did some better repeated studies that were far more controlled. And they started finding detrimental effects of taking escogenes, ketones for endurance performance. So, I mean, why were people taking ketones? The idea is if you go into a ketatonic state, which is like a fasted state, instead of it preserves your glycogen stores for longer in the note that
you you would be using more fat or ketones for energy production instead of glycogen, is your sugar stores, saving your sugar stores for later in the race. The logic makes sense. One of the problems with it is if you're in a race and you do a high intensity effort, your body can't selectively go and use ketones. It's still going to go use glycogen because the way it works is these things have a rate of synthesis to produce ATP. And, you know, when we want to do a high intensity effort,
It uses an anaerobic system with glycolysis. You can't really avoid that. There's no way for your body to go use ketones to produce 400 Watts in a few seconds. Right. You've got to use phosphocreatine for the first five seconds. And then you run into your anaerobic and your glycolysis system to produce energy that quick. So, I mean, we started to have repeated evidence that shows actually people perform worse when they're taking it. So they've done blinded studies on race walkers.
and Maranfonas, I think they've also now done it on cyclists and had the same result where the group that was on the ketones performed worse in their time trials.
Cam Nicholls (36:58.926)
us in
Ben Treble (37:04.686)
Cause there's still some studies that show mixed results. Like some individuals do still do better with it. And there's still, know, we're talking about small sample sizes here where there's, know, probably two, three studies that show it has a bad, a negative effect. But then there's still arguably, you know, four or five papers that show inconclusive results. And there's a couple of papers that were sponsored by the companies that showed positive results. So, so it still sits in this mixed outcomes.
Or it's an emerging supplement. So we still want to keep an eye on it because it's still logic says we need to do more research. It's safe to take, it's accessible. And maybe if we do more research, we'll find something out, but I'm certainly not hopeful and I'm not taking ketones. Yeah.
Cam Nicholls (37:49.334)
Interesting. think when I was kind of, so I was over in sort of France the last two years with Ketone IQ actually, as a sponsor of Isma and from what I could gather, you know, that they do hold their cards slightly close to their chest, but ketones were taken more as a recovery drink than actually a performance enhancing drink.
Ben Treble (38:10.542)
think that's where this paper, you gotta be mindful this paper is all about performance and they're not really focused on recovery as much. So that would be also what I may expect in the future that we find out if you're doing multi-day events where recovery is really important, maybe there's a very marginal gain to be had in terms of recovery from taking ketones post-race, but not in the race or loading pre-race, expecting high power output in the race because you took ketones.
The only reason you'd have this performance benefit is if it lets you recover a little bit better every day in a three week grand tour, by the end of the third week, maybe you can do a higher power output because you've been recovering better a little bit every day accumulated for three weeks. Yep. So that would be my guess as to why Yumbo taking it. Maybe it's also cause they're probably getting a lot of funding from them to take it. You know, there's always that bias. Cool. Yeah. You don't see them downing shots anymore in the ProPello. You used to see teams.
smashing shots mid event. Yeah. And don't see teams and teams used to take it who weren't sponsored by ketone companies. And I think the biggest proof in the pudding here is you no longer see that happening. Or I don't, I haven't seen it. I don't see pro writers who are not sponsored by ketone company taking ketones anymore or spending their money on ketones.
Cam Nicholls (39:27.182)
Yeah, no, I think it's, you know, from the because we need to have a chat with the nutritionists from Visma last year. And I think they're so drilled in on calorie intake and carbohydrate intake during the race that ketones don't make the carbs are better for performance. You know, going back to the start of this conversation, get your macro nutrients right. If you want to perform in a race, know, carbs is the focus.
That's a really comprehensive list, Ben. I think we'll end it there because we've been on this topic for quite a long period of time. But I think what it does shine a light on is, you if people are out there listening and they want to start, you know, implementing some supplements into their regime, do it strategically. Don't just start, as you said, grabbing anything that pops up in your marketing feed. Look at credible lists and maybe we can dump, you know, the AIS list or link.
in the podcast description as well as the link to the research paper. But I think as well, like if you know, if you're working with a coach, know, Ben's an RCA coach and you know, he's working with his members, not just on training, but also on supplementation and when to bring it in and how to bring it in. So if you're looking to bring supplementation into your training, you're interested in working with a coach, make sure you check out the RCA's website, www.roadcyclingacademy.com. Check out One to One Coaching and you can find a coach there. We'll catch you all in the next podcast.