Psychopharmacology and Psychiatry Updates

In this episode, we examine a surprising repurposing of ondansetron — a common antiemetic — as a potential adjunctive treatment for the notoriously hard-to-treat negative symptoms of schizophrenia. Could a nausea medication help restore motivation and emotional engagement in your patients with residual symptoms despite stable antipsychotic therapy?
Faculty: Oliver Freudenreich, M.D.
Host: Richard Seeber, M.D.
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Earn 0.5 CMEs: Quick Take Vol. 81
Is Ondansetron Effective for Negative Symptoms in Schizophrenia?

In this episode, we explore how to manage SSRI treatment in pregnant patients — addressing common fears around fetal malformations, medication switching, and neonatal withdrawal. Can stopping an antidepressant actually do more harm than continuing it?
Faculty: Amanda Koire, M.D.
Host: Richard Seeber, M.D.
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Earn 0.5 CME: Prescribing in Pregnancy: What Every Clinician Should Know
SSRI Treatment During Pregnancy: A Clinical Case

In this episode, we explore a landmark meta-analysis that challenges decades of fear surrounding IV haloperidol and cardiac risk. Could one of medicine's most persistent myths be costing patients their best treatment option for delirium? Dr. Scott Beach breaks down the evidence.
Faculty: Scott Beach, M.D.
Host: Richard Seeber, M.D.
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Earn 0.75 CMEs: Quick Take Vol. 80
IV Haloperidol: Are Cardiac Safety Concerns Overblown?

In this episode, we explore the complex risk-versus-risk decision of using lithium during pregnancy and breastfeeding. How do you weigh the near-certainty of mood relapse against fetal cardiac risks? Dr. Amanda Koire provides a practical framework every clinician needs when managing bipolar disorder in reproductive-age women.
Faculty: Amanda Koire, M.D.
Host: Richard Seeber, M.D.
Learn more about our memberships here
Earn 0.5 CME: Prescribing in Pregnancy: What Every Clinician Should Know
Lithium in Pregnancy and Breastfeeding

In this episode, we explore new international guidelines for clozapine monitoring following the FDA's REMS rescission. Should patients on stable clozapine continue lifelong monthly blood draws, or can we safely reduce monitoring after two years? Dr. Seeber discusses how these evidence-based recommendations balance patient burden with safety.
Faculty: Oliver Freudenreich, M.D.
Host: Richard Seeber, M.D.
Learn more about our membership here
Earn 0.75 CMEs: Quick Take Vol. 79
New Guidelines for Clozapine ANC Monitoring