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Digital Pathology Podcast

Aleksandra Zuraw, DVM, PhD
Digital Pathology Podcast
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  • 167: Future of Pathology AI, Training & The Next Generation of Diagnostics
    Send us a textLive from Pathology Visions 2025 in San Diego, I share highlights from Day 2 of the world’s leading digital pathology conference, where experts explored how AI, empathy, and training are shaping the next generation of pathologists.This episode captures the shift from technology as a tool to technology as a bridge — helping us connect with patients in more meaningful ways.What I Talk About1️⃣ From Pixels to Patients We’ve built the infrastructure; now it’s about applying it. Pathology is no longer just digital — it’s personal, accessible, and human-centered.2️⃣ Dr. Leah Lijah Joseph’s Keynote — Pathologists as Patients Dr. Joseph, a cancer pathologist and survivor, shared her journey from diagnosing others to understanding her own slides. She now runs a patient pathology clinic, empowering people to see and learn from their own tissue samples.3️⃣ The Power of Visualization Dr. Joseph described how visualization and mental imagery support healing — a reminder that empathy and imagination can coexist with precision science.4️⃣ AI & Imaging Innovation From Google Research’s JPEG AXL format reducing file size by 30%, to discussions on color fidelity with DICOM’s David Clooney, we explored how innovation and accuracy must move hand-in-hand.5️⃣ Cytology Goes Digital With Hologic’s Genius Digital Diagnostic and AIXMed’s AI-assisted QC, cytology is entering a new era — faster, more accurate, and fully traceable through 100% AI quality control.6️⃣ The Human Side of AI I also share a personal story about my mother’s medical experience — and how even with all the tech, empathy remains the missing link. AI can’t replace compassion, but it can help us focus on it by automating what takes time away from patients.Key TakeawaysAI is enhancing accuracy and accessibility in diagnostics.Pathologists are taking on more patient-facing roles.Cytology digitization is revolutionizing quality and speed.Innovation must balance efficiency with color and data integrity.Empathy and communication will always define great medicine.I hope this episode helps you see how AI, empathy, and education are shaping the next era of diagnostics.Let’s continue building the bridge from pixels to patients, one slide at a time. 💡#PathVision25Support the showGet the "Digital Pathology 101" FREE E-book and join us!
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  • 165: How AI Is Changing Cancer Diagnosis Insights from PathVision 2025
    Send us a textLive from Pathology Visions 2025 in beautiful San Diego, I sat down with Imogen Fitt from Signify Research to explore how AI, digital pathology, and interoperability are transforming the way we diagnose cancer and deliver patient care.The conference theme, “From Pixels to Patients,” perfectly captures this year’s shift — from theoretical discussions about AI to real-world implementation and measurable outcomes.We’re no longer just asking “what can AI do?” — we’re seeing how it’s actually improving accuracy, reducing barriers, and connecting pathologists and labs worldwide.What We Discuss1️⃣ From Hype to Application This year, the buzz wasn’t about AI’s potential — it was about how it’s being used. We highlight case studies showing how digital tools are reducing diagnostic errors, improving collaboration, and even helping smaller labs digitize faster and more affordably.2️⃣ PathPresenter’s Expanding Role We dive into PathPresenter’s innovative model that gives users access to digital pathology at no initial cost, opening the door for over 75,000 professionals across 62 institutions. I share why I personally use PathPresenter for teaching and how it’s helping lower the barrier to entry for education, consultations, and patient care.3️⃣ New Scanning Technology and Accessibility We talk about compact scanners like Grundium’s four-slide scanner and new miniature models that make digitization possible even in smaller labs. The message is clear: you don’t need a massive system to start going digital.4️⃣ Collaboration and AI in Action Imogen shares updates from across Europe and Asia, including how hospitals are tackling storage, AI regulation, and workflow efficiency. We discuss emerging partnerships—Fujifilm, Voicebrook, Dolby, and others—that are making voice dictation, chat agents, and real-time AI insights part of the modern pathology cockpit.5️⃣ The Human Side of AI Adoption We also reflect on how digital pathology is changing careers and training. Younger pathologists expect digital tools as part of their workflow — and many won’t settle for less. We discuss how this new generation is driving adoption and pushing institutions to modernize.My ReflectionsI still remember when digital pathology felt intimidating — when only a few people were “allowed” to touch the scanner. But today, that’s changed completely.Now, we’re living in an era where AI and digital pathology are not optional — they’re essential. The technology has matured, and so has the mindset around it. What excites me most is seeing how collaboration and accessibility are becoming central to innovation.Key TakeawaysAI in pathology is moving from hype to practice — focused on improving patient outcomes.Accessibility matters: smaller, affordable scanners and open platforms are democratizing digital pathology.Collaboration between vendors, clinicians, and technologists is key to faster, smoother adoption.The next generation of pathologists expects — and demands — a digital-first workflow.Listen Now to Learn:How AI is reshaping cancer diagnosisThe tools driving real change in labs todayHow collaboration fuels digital transformation in pathologySupport the showGet the "Digital Pathology 101" FREE E-book and join us!
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  • 164: What Happens to Human Expertise When AI Takes Over in Medicine
    Send us a textWill AI make doctors and specialists less skilled—or even replace them?That’s the question I explore in this episode of DigiPath Digest #29. As someone working where AI meets digital pathology, I’m both excited and cautious about how automation shapes our skills and professional identity.In this episode, I discuss two studies that ask tough questions about AI, expertise, and the future of medicine.What I Talk About:1️⃣ Endoscopist Deskilling After AI Exposure (Lancet, 2025)A multicenter Polish study found that after frequent AI-assisted colonoscopy use, endoscopists’ adenoma detection rate dropped by ~6% when performing procedures without AI. It suggests overreliance on automation can subtly dull vigilance.It reminded me of how we depend on GPS instead of remembering routes—or how driving an automatic car changes focus. Could medicine be facing a similar shift?2️⃣ “Will My Expertise Be Devalued by Machines?” (Bangladesh, 2024)Healthcare professionals shared concerns about:Job security and evolving roles 💼Ethics, accountability, and trust ⚖️Losing the human touch ❤️The need for AI training and oversight 📚AI adoption isn’t just technical—it’s behavioral, cultural, and deeply human.My Take:I see AI as a partner, not a threat. I use it every day for research and content, but I never outsource judgment. AI can boost efficiency—but only if we stay curious, critical, and engaged.We can’t let convenience replace competence. AI should augment our expertise, not erode it.🌍 PathVision 2025 — Sept 5–7, 2025I’m also thrilled to share that I’ll be livestreaming PathVision 2025 from September 5–7, 2025, on LinkedIn and YouTube! 🎥This year’s conference is packed with innovations in AI, digital pathology, and cancer diagnostics. I’ll bring you live insights, interviews, and key takeaways from the sessions—so mark your calendars and tune in!🧩 Key TakeawaysContinuous AI use may lower independent performance.Professionals worry about trust, ethics, and losing skill.The goal isn’t to resist AI—but to use it critically and consciously.The best outcomes happen when AI and human expertise work together.🕒 Episode Highlights00:00–06:14 | Welcome & PathVision preview06:14–17:46 | AI deskilling question08:27–14:05 | Colonoscopy study results27:11–38:10 | Healthcare workers’ AI concerns43:59–51:05 | Reflections & responsible AI use51:05–52:55 | Closing thoughts + PathVision invite🧭 MentionedLancet Gastroenterology & Hepatology (2025): “Endoscopist deskilling risk after AI exposure”Bangladesh Study (2024): “Will my training be devalued by machines?”My Book: Digital Pathology 101 (Updated Edition Coming Soon)Event: PathVision 2025 – Sept 5–7, 2025 (Streaming Live!)Thanks for listening to DigiPath Digest #29! I hope it inspires you to think critically about how we can embrace AI without losing what makes us human.And don’t miss PathVision 2025 (Sept 5–7, 2025)—I’ll be streaming it live for three days of insights, innovation, and community. Let’s keep learning and leading the future of digital pathology togSupport the showGet the "Digital Pathology 101" FREE E-book and join us!
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  • 163: Digital Diagnostics Summit 2025 Innovation in Action - Conference Update
    Send us a textWhat if climbing the digital pathology “mountain” isn’t about reaching the summit alone—but knowing where base camp is, and who you bring with you?In this episode, I take you inside the Digital Diagnostic Summit in Park City, hosted by Lumea, where fewer than 100 digital pathology leaders gathered to share their journeys, challenges, and solutions. From resilient metaphors of Everest climbs to practical strategies for workflow ownership, clinical trials, and AI-powered biomarkers, this summit showed that the future of diagnostics is built on collaboration, purpose-driven adoption, and trust in data custodianship.🔑 Highlights with Timestamps[00:03–01:49] Summit kickoff – “Climbing the Digital Pathology Mountain” theme and why this summit feels different.[01:49–03:38] Everest keynote – lessons in resilience and why failure is part of innovation.[03:38–06:02] Collaboration over competition – why base camp is as important as the summit.[06:02–09:18] Workflow ownership – defining value-driven outcomes before choosing tools.[09:18–11:35] Data custodianship – protecting patient privacy while enabling ethical research.[11:35–15:16] Panel insights – choosing digital tools that integrate into workflows and prevent burnout.[15:16–17:31] Horseback networking – why informal conversations matter as much as panels.[17:31–19:18] Emerging health tech – 3D printing prosthetics and synthetic blood innovations.[19:18–23:54] Personalized biomarkers – outcome-driven diagnostics that move beyond human scoring.[23:54–29:16] Digital pathology in trials – Aperture platform launch and patient stratification in global studies.[29:16–31:42] Community impact – stories of career transformation and remote adoption.[31:42–32:37] Closing thoughts – why intimate summits accelerate adoption and what’s next.📚 Resources from this EpisodeFDA Journal of Pathology & Informatics – Research on data custodianship and ethical use.Proscia Aperture Platform – New tool for clinical trial management and patient identification.Astro Zenica Digital Biomarker – Personalized biomarker validated by outcomes.Barco Healthcare White Paper – Why display quality matters in pathology..✨ Key Insights from the Summit✔ Success in digital pathology is not about scaling alone—partnerships matter. ✔ Labs must own their workflows and define outcomes before adopting tools. ✔ Data custodianship is central for protecting privacy while advancing research. ✔ Personalized biomarkers are shifting diagnostics toward outcome-driven AI. ✔ Clinical trials benefit from digital pathology in patient selection and stratification. ✔ Intimate summits provide mentorship, collaboration, and career transformation. ✔ Exciting health tech—from synthetic blood to 3D printing—complements digital pathology innovation.Support the showGet the "Digital Pathology 101" FREE E-book and join us!
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  • 162: How Color Impacts Every Diagnosis |Color Calibration in Digital Pathology w/ Tom Kimpe (Barco) and Monika Lamba Saini
    Send us a textWhat if up to 35% of the diagnostic color data on your pathology slides never reaches your eyes—just because of your monitor? In this episode, sponsored by Barco, I sit down with Dr. Monika Lamba Saini (ADC Therapeutics) and Tom Kimpe (Barco) to uncover why color calibration in digital pathology isn’t optional anymore—it’s critical for diagnosis, efficiency, and AI readiness.Highlights:[00:03:42] Monika’s path from CROs to biopharma and why color consistency matters in clinical trials.[00:09:22] What “color science” means in pathology and why color is one-third of diagnosis.[00:12:40] When the same tissue looks different across labs and scanners—and how this causes diagnostic conflicts.[00:16:19] Why HER2 scoring and IHC rely on color intensity—and how poor color fidelity lowers diagnostic confidence.[00:18:34] Research showing up to 35% of H&E slide colors fall outside of the sRGB color space—meaning you never see them on a standard monitor.[00:22:23] Where the biggest sources of color variability occur across the imaging chain come from.[00:26:26] Calibrated displays and pathologist speed—why confidence = faster reads.[00:35:19] How monitors degrade over time and why calibration is essential.[00:41:27] Why choosing a monitor based on price is short-sighted—and the real ROI of medical-grade displays.[00:43:45] ICC profiles explained: the missing piece in end-to-end color consistency.[00:52:48] Training pathologists on color literacy and internal calibration strategies.[01:00:10] How color variability affects AI algorithm accuracy—up to a 30% drop if scanners differ.[01:14:57] The role of professional societies in building color literacy and regulatory guidance.[01:22:30] Final takeaways: if you’re skeptical about calibration, here’s why you should care.Resources from this EpisodeFDA Research by Cheng – H&E slide colors beyond sRGB Reproducible Color Gamut of Hematoxylin and Eosin Stained Images in Standard Color Space. Barco White Paper – The Importance of Color in Modern Pathology.Barco eBook – Digital Pathology: What Are The BenefitsBarco MDPC-8127 Monitor – Medical-grade display optimized for pathology.Digital Pathology 101 (by me, Dr. Aleksandra Zuraw) – Free PDF & Amazon print edition.Support the showGet the "Digital Pathology 101" FREE E-book and join us!
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About Digital Pathology Podcast

Aleksandra Zuraw from Digital Pathology Place discusses digital pathology from the basic concepts to the newest developments, including image analysis and artificial intelligence. She reviews scientific literature and together with her guests discusses the current industry and research digital pathology trends.
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