Episode 142 - Continuing vs. Withholding RAS inhibitors before Surgery
Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent systematic review and meta-analysis that looks at continuing versus withholding RAS inhibitors before noncardiac surgery. Here we go!Evaluating the risks and benefits of continuing versus withholding renin–angiotensin system inhibitors: a systematic review and meta-analysis with trial sequential analysis (0:00 – 8:20).The Good Stuff (8:21 – 9:44):NotebookLMQuestions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
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Episode 141 - Spironolactone in Patients on Maintenance Dialysis and Prophylactic Antibiotics for Upper GI Bleed in Cirrhosis
Send us a textWelcome back Rounds Table Listeners! We are back today with a Classic Rapid Fire episode. This week, Drs. Mike and John Fralick discuss two recent papers: the effects of spironolactone on heart failure and cardiovascular death in patients undergoing maintenance dialysis, and antibiotic prophylaxis in patients with cirrhosis and upper gastrointestinal bleeding. Two papers, here we go!Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial (0:00 – 7:19)Prophylactic Antibiotics for Upper Gastrointestinal Bleeding in Patients With Cirrhosis: A Systematic Review and Bayesian Meta-Analysis (7:20 – 15:08)And for the Good Stuff (15:09 – 17:51):The $500m slugger who helped Canada get to the World SeriesClinical practice guidelines one-pagers coming soon to Trial Files: https://trialfiles.substack.com/Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
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TBT - Airway Management in Acute Poisoning and the PALACE Trial
Send us a textWelcome back Rounds Table Listeners! In this throwback episode (initial release 14 Mar 2024), Dr. Mike Fralick and special guest, Dr. Laiya Carayannopoulos from the Intern at Work Podcast, discuss two papers: one exploring the role of non-invasive ventilation in comatose patients after acute poisoning, and and one on the use of the PEN-FAST Score in the point-of-care risk assessment of penicillin allergy. Two papers, here we go!Effect of Noninvasive Airway Management of Comatose Patients With Acute Poisoning (0:00 – 16:25).Efficacy of a Clinical Decision Rule to Enable Direct Oral Challenge in Patients With Low-Risk Penicillin Allergy (16:26 – 24:17).And for the Good Stuff:Celebrating Research Success! (24:18 – 25:14).Non-inferiority results: everything you need know in 5 minutes! and Is Noninferior Not Inferior? (25:15 – 26:48).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
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Episode 140 - Spironolactone vs. Amiloride for Resistant Hypertension
Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent trial examining whether amiloride is noninferior to spironolactone in reducing systolic blood pressure in patients with resistant hypertension. Here we go!Spironolactone vs Amiloride for Resistant Hypertension: A Randomized Clinical Trial (0:00 – 8:10).Run-in studies:Application and impact of run-in studiesApplication and Impact of Run-In Studies for the Evaluation of Statin Efficacy and SafetyThe Good Stuff (8:11 - 9:14):Trial Files: https://trialfiles.substack.com/Heme Onc Trial Files: https://hemeonctrialfiles.substack.com/Allergy & Immunology Trial Files: https://allergyimmtrialfiles.substack.com/Critical Care Trial Files: https://criticalcaretrialfiles.substack.com/Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
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Episode 139 - Semaglutide in Alcohol Use Disorder
Send us a textWelcome back Rounds Table Listeners! Today we have a solo episode with Dr. Mike Fralick. This week, he discusses a recent phase 2 trial looking at the effects of once-weekly semaglutide on alcohol consumption and craving in adults with alcohol use disorder (AUD). Here we go!Once-Weekly Semaglutide in Adults With Alcohol Use Disorder (0:00 – 10:28).Questions? Comments? Feedback? We’d love to hear from you! @roundstable @InternAtWork @MedicinePods
The Rounds Table is a free recurring medical podcast covering the latest and most important research from major medical journals. It is intended for all practicing healthcare professionals and aims to to help them keep up to date in the care of their patients.
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