The Obesity Guide with Matthea Rentea MD

Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
For decades, Jacqui Cook lived in a cycle many women know all too well: losing weight, gaining it back, and starting over… always wondering why nothing seemed to stick. Food was her love language, life kept getting in the way, and no matter how hard she tried, maintaining her progress felt impossible.
Everything changed after a wake-up moment that led her to try a GLP-1 medication. Now, 115 pounds lighter, Jacqui shares the real, honest side of her journey: navigating maintenance, facing the fear of regain, letting go of guilt, rebuilding lost muscle, and learning to live fully in her body. She also reveals the diet habit she finally ditched, and why it turned out to be one of the best decisions of her life.

References
Body Composition Mini Course
Get the free podcast roadmap for The Obesity Guide
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
If you want to go deeper into the science of fat loss, muscle preservation, and what your body composition numbers actually mean, check out my course Body Composition Decoded, where I break it all down in a clear, practical way.
Support the show

Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
You hit your goal weight. So now what...?
For a lot of people, maintenance feels like uncharted territory. And without the right mindset, it's easy to either white-knuckle it or slowly drift back to old patterns. 
In this episode, I walk through five things I think everyone needs to know about maintenance: why it's not a new phase, how to find the weight you can actually live at, how to monitor without judgment, what to do when your metabolism adapts, and what long-term GLP-1 use really looks like.
References
Body Composition Mini Course
Five Mistakes that People Make on a GLP- 1 Mini Course
Get the free podcast roadmap for The Obesity Guide
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
If you want to go deeper into the science of fat loss, muscle preservation, and what your body composition numbers actually mean, check out my course Body Composition Decoded, where I break it all down in a clear, practical way.
Support the show

Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
There’s a lot of noise online about semaglutide, sudden vision loss, and scary eye complications. If you’re taking a GLP-1 (or thinking about it), you might be wondering: Am I putting my vision at risk? 
In this episode, I sit down with Dr. Mina Farahani, a cornea, cataract, and refractive specialist, to get the real story on GLP-1s and eye health. We cover what the latest data actually says about vision loss risk, why a baseline eye exam matters before starting treatment, what symptoms should never be ignored, and the simple habits that protect your eyesight long-term.
References
Connect with Dr. Mina Farahani:
Instagram
Website

Get the free podcast roadmap for The Obesity Guide

Audio Stamps
01:40 - Meet ophthalmologist Dr. Mina Farahani, answering all your GLP-1 and eye health questions.
02:52 - GLP-1s and sudden vision loss: what NAION is and how low the risk actually is.
06:24 - What to ask for at your eye exam.
07:16 - Should you get an eye exam before starting a GLP-1? 
09:10 - Eye symptoms that should never wait for further attention.
11:00 - Dr. Mina's top tips for protecting your eyesight long-term.
13:16 - Contrave, Qsymia, and eye pressure: what you need to know.
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
If you want to go deeper into the science of fat loss, muscle preservation, and what your body composition numbers actually mean, check out my course Body Composition Decoded, where I break it all down in a clear, practical way.
Support the show

Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
Back on your GLP-1 medication… but confused why it isn’t working this time?
Lots of people stop these medications for valid reasons. Cost, side effects, pregnancy plans, or simply because things were going well and it felt like the right time to try managing without them. But when weight creeps back on and you restart, it can feel really frustrating when results don’t look the same.
In this episode, I talk through why that happens. Factors like muscle loss, metabolism changes, weight regain patterns, and higher stress levels can all change how your body responds the second time around. If you’re feeling stuck or wondering what changed, this episode will help you make sense of what’s going on and figure out your next steps without beating yourself up.
References
Get the free podcast roadmap for The Obesity Guide
Jane Pilger: The Gathering
A monthly guided experience to help you slow down and learn how to trust yourself.

Slowing Down to the Speed of Joy by Matthew Kelly 
Back to Basics Mini Podcast Series 2025
Ep. 100: Hydration
Ep. 101: Protein
Ep. 102: Fiber
Audio Stamps
00:30 - Why GLP-1 medications may stop working when you restart them after taking a break.
01:20 - Book recommendation: "Slowing Down to the Speed of Joy" and how constant busyness prevents you from addressing behaviors that aren't serving you.
04:04 - The common pattern: success, stopping medication, weight regain, then struggling when restarting.
06:25 - Why it's harder the second time: muscle loss, weight cycling, and mismanaged expectations all impact your results.
09:00 - The importance of updated lab work and comprehensive metabolic assessment before restarting.
10:35 - How chronic stress and high cortisol prevent weight loss, even on medication.
14:35 - The real work: learning nervous system regulation instead of constantly fighting cravings and urges.
All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
If you want to go deeper into the science of fat loss, muscle preservation, and what your body composition numbers actually mean, check out my course Body Composition Decoded, where I break it all down in a clear, practical way.
Support the show

Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
If you've noticed your sex drive has tanked, whether from GLP-1s, perimenopause or menopause, postpartum changes, or simply the mental load of being a woman in 2026… you're not imagining it. And you're definitely not “broken”.
In this episode, I talk with Dr. Kristen Wolfe, OB-GYN and women's sexual health specialist at Evermore Women's Health. She breaks down why 85% of women experience desire differently than we're told and what’s actually behind the drop in libido so many women experience.
We talk about how hormones, stress, medications, busy lives, and relationship dynamics all play a role, and why so many women blame themselves for changes that are completely normal. Dr. Wolfe also shares practical strategies that can help, from understanding responsive desire and reducing the “brakes” on libido, to scheduling intimacy, practicing mindfulness, and using tools like arousal creams or medical treatments when appropriate.
References
Connect with Dr. Kristen Wolfe
https://www.evermorewomenshealth.com/
https://www.kristenwolfemd.com/
Books:
Come As You Are — Emily Nagoski
You Are Not Broken — Kelly Casperson
A Tired Woman’s Guide to Passionate Sex — Laurie Mintz
Better Sex Through Mindfulness — Lori Brotto
Becoming Cliterate — Laurie Mintz
Online resources:
Dipsea, an app offering erotic audio stories designed for women
OMGYes, an educational platform where women share techniques and insights about pleasure and orgasm
The International Society for the Study of Women's Sexual Health (ISSWSH)
Products:
Vella Bioscience
Überlube
Documentary:
The Pink Pill: Sex, Drugs and Who Has Control

All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
If you want to go deeper into the science of fat loss, muscle preservation, and what your body composition numbers actually mean, check out my course Body Composition Decoded, where I break it all down in a clear, practical way.
Support the show