PodcastsHealth & WellnessThe Obesity Guide with Matthea Rentea MD

The Obesity Guide with Matthea Rentea MD

Matthea Rentea MD
The Obesity Guide with Matthea Rentea MD
Latest episode

212 episodes

  • The Obesity Guide with Matthea Rentea MD

    GLP-1s and Vision Loss: Separating Fact from Fear with Dr. Mina Farahani

    2026/03/02 | 17 mins.
    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
    There’s a lot of noise online about semaglutide, sudden vision loss, and scary eye complications. If you’re taking a GLP-1 (or thinking about it), you might be wondering: Am I putting my vision at risk? 
    In this episode, I sit down with Dr. Mina Farahani, a cornea, cataract, and refractive specialist, to get the real story on GLP-1s and eye health. We cover what the latest data actually says about vision loss risk, why a baseline eye exam matters before starting treatment, what symptoms should never be ignored, and the simple habits that protect your eyesight long-term.
    References
    Connect with Dr. Mina Farahani:
    Instagram
    Website

    Get the free podcast roadmap for The Obesity Guide

    Audio Stamps
    01:40 - Meet ophthalmologist Dr. Mina Farahani, answering all your GLP-1 and eye health questions.
    02:52 - GLP-1s and sudden vision loss: what NAION is and how low the risk actually is.
    06:24 - What to ask for at your eye exam.
    07:16 - Should you get an eye exam before starting a GLP-1? 
    09:10 - Eye symptoms that should never wait for further attention.
    11:00 - Dr. Mina's top tips for protecting your eyesight long-term.
    13:16 - Contrave, Qsymia, and eye pressure: what you need to know.
    All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

    If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
    Not Sure Where to Start With the Podcast? I’ve Got You.
    Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.

    Support the show
  • The Obesity Guide with Matthea Rentea MD

    Restarting GLP-1s? 5 Reasons It Feels Harder This Time

    2026/02/23 | 19 mins.
    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
    Back on your GLP-1 medication… but confused why it isn’t working this time?
    Lots of people stop these medications for valid reasons. Cost, side effects, pregnancy plans, or simply because things were going well and it felt like the right time to try managing without them. But when weight creeps back on and you restart, it can feel really frustrating when results don’t look the same.
    In this episode, I talk through why that happens. Factors like muscle loss, metabolism changes, weight regain patterns, and higher stress levels can all change how your body responds the second time around. If you’re feeling stuck or wondering what changed, this episode will help you make sense of what’s going on and figure out your next steps without beating yourself up.
    References
    Get the free podcast roadmap for The Obesity Guide
    Jane Pilger: The Gathering
    A monthly guided experience to help you slow down and learn how to trust yourself.

    Slowing Down to the Speed of Joy by Matthew Kelly 
    Back to Basics Mini Podcast Series 2025
    Ep. 100: Hydration
    Ep. 101: Protein
    Ep. 102: Fiber
    Audio Stamps
    00:30 - Why GLP-1 medications may stop working when you restart them after taking a break.
    01:20 - Book recommendation: "Slowing Down to the Speed of Joy" and how constant busyness prevents you from addressing behaviors that aren't serving you.
    04:04 - The common pattern: success, stopping medication, weight regain, then struggling when restarting.
    06:25 - Why it's harder the second time: muscle loss, weight cycling, and mismanaged expectations all impact your results.
    09:00 - The importance of updated lab work and comprehensive metabolic assessment before restarting.
    10:35 - How chronic stress and high cortisol prevent weight loss, even on medication.
    14:35 - The real work: learning nervous system regulation instead of constantly fighting cravings and urges.
    All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

    If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
    Not Sure Where to Start With the Podcast? I’ve Got You.
    Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.

    Support the show
  • The Obesity Guide with Matthea Rentea MD

    Perimenopause, GLP-1s, and What's Actually Affecting Your Sex Drive with Dr. Kristen Wolfe

    2026/02/16 | 56 mins.
    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
    If you've noticed your sex drive has tanked, whether from GLP-1s, perimenopause or menopause, postpartum changes, or simply the mental load of being a woman in 2026… you're not imagining it. And you're definitely not “broken”.
    In this episode, I talk with Dr. Kristen Wolfe, OB-GYN and women's sexual health specialist at Evermore Women's Health. She breaks down why 85% of women experience desire differently than we're told and what’s actually behind the drop in libido so many women experience.
    We talk about how hormones, stress, medications, busy lives, and relationship dynamics all play a role, and why so many women blame themselves for changes that are completely normal. Dr. Wolfe also shares practical strategies that can help, from understanding responsive desire and reducing the “brakes” on libido, to scheduling intimacy, practicing mindfulness, and using tools like arousal creams or medical treatments when appropriate.
    References
    Connect with Dr. Kristen Wolfe
    https://www.evermorewomenshealth.com/
    https://www.kristenwolfemd.com/
    Books:
    Come As You Are — Emily Nagoski
    You Are Not Broken — Kelly Casperson
    A Tired Woman’s Guide to Passionate Sex — Laurie Mintz
    Better Sex Through Mindfulness — Lori Brotto
    Becoming Cliterate — Laurie Mintz
    Online resources:
    Dipsea, an app offering erotic audio stories designed for women
    OMGYes, an educational platform where women share techniques and insights about pleasure and orgasm
    The International Society for the Study of Women's Sexual Health (ISSWSH)
    Products:
    Vella Bioscience
    Überlube
    Documentary:

    All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

    If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
    Not Sure Where to Start With the Podcast? I’ve Got You.
    Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.

    Support the show
  • The Obesity Guide with Matthea Rentea MD

    Understanding PCOS: From Diagnosis to Long-Term Health with Dr. Sabrina Huq

    2026/02/09 | 49 mins.
    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
    If you’ve been told you have PCOS (or suspect you might), you’ve probably been left with more questions than answers. It’s one of the most misunderstood conditions out there, and a lot of people are misdiagnosed, under-treated, or given the same tired advice: “just lose weight” or “take the pill and see.” 
    In this episode, I’m joined by endocrinologist Dr Sabrina Huq to clear things up. We talk about what PCOS actually is, how to get properly diagnosed (including the key lab tests), and why spotting it early can change your long-term health, including your ability to have a healthy, natural pregnancy. Tune in for Dr Huq’s practical approach to managing PCOS through food, movement, sleep and stress, plus when meds like metformin or GLP-1s might make sense.
    References
    Flo.health 

    Connect with Dr. Sabrina Huq:
    Instagram
    Tiktok
    Clinic

    Audio Stamps
    01:08 – Dr. Sabrina Huq introduces herself and her approach to treating PCOS patients.
    02:26 – What PCOS actually is and why you don't need ovarian cysts to have it.
    06:45 – The essential labs to diagnose PCOS and rule out serious conditions.
    15:15 – Diet strategies for elevated blood sugar: why breakfast and whole foods matter.
    22:34 – Exercise that works: strength training three times weekly and post-meal movement.
    27:35 – Why stress management and sleep quality are critical for PCOS symptoms.
    28:45 – Hidden endocrine disruptors in plastics and takeout + simple swaps to reduce exposure.
    32:57 – Dr. Huq's supplement approach: prenatals and vitamin D over trendy options.
    38:12 – What CGM reveals about insulin resistance in PCOS patients.
    43:06 – Why early diagnosis matters and the reality of GLP-1s for young PCOS patients.
    All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

    If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
    Not Sure Where to Start With the Podcast? I’ve Got You.
    Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.

    Support the show
  • The Obesity Guide with Matthea Rentea MD

    Your Friday Five: Season One Wrap + A Short Hiatus

    2026/02/06 | 3 mins.
    Send a Text Message. Please include your name and email so we can answer you! Please note, this does not subscribe you to our email list, it's just to answer if you have a questions for us.
    All of the information on this podcast is for general informational purposes only. Please talk to your physician and medical team about what is right for you. No medical advice is being on this podcast.

    If you live in Indiana or Illinois and want to work with doctor Matthea Rentea, you can find out more on www.RenteaClinic.com
    Not Sure Where to Start With the Podcast? I’ve Got You.
    Get my free Podcast Roadmap—a simple guide to help you find the episodes that matter most to your journey. Whether you're on GLP-1s, navigating plateaus, or just starting out, there's something here for you.

    Support the show

More Health & Wellness podcasts

About The Obesity Guide with Matthea Rentea MD

Matthea Rentea MD leads discussions on obesity and chronic weight management. Her guests range from experts in the fields that intersect with obesity and wellness, to individuals successful in their weight journey. She is a Board certified Internal Medicine and Diplomate of the American Board of Obesity Medicine and founder of the Rentea Metabolic Clinic, a Telehealth clinic for residents of the state of Indiana and Illinois that helps comprehensively with weight management. This podcast is for information and education purposes only. No medical advice is being given. Please talk to your physician for what is right for you.
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