GLP-1 Hub: Support, Community, and Weight Loss

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If breast cancer runs in your family, you may be wondering whether you're getting the right screening and what else you can do to lower your risk. Ana Reisdorf talks with Dr. Anne Peled about how GLP-1s may shift the balance, what everyday habits you should build, and why weight can become harder to manage during and after treatment. You'll learn which questions to bring to your care team, how to protect your nutrition, and what emerging GLP-1 research still hasn't answered.

**IN THIS EPISODE**

- How family history and breast density can shape your screening conversation
- Exercise, alcohol, and food choices in the discussion about lowering breast cancer risk
- Why weight, inflammation, and cancer risk are more complicated than a single cause
- What early GLP-1 research suggests, and why prevention questions remain unanswered
- Why hormone-blocking medications and other cancer treatments can affect weight
- Protecting protein and nutrient intake while coordinating weight management with cancer care
- Personalized treatment, emerging research, and advocating for yourself

**ABOUT THE GUEST**

Dr. Anne Peled is a breast cancer and reconstructive surgeon in San Francisco and a two-time breast cancer survivor. She earned her medical degree at Harvard Medical School and completed plastic and reconstructive surgery training and a breast surgical oncology fellowship at UCSF. She is co-director of the Breast Care Center of Excellence at Sutter Health California Pacific Medical Center. Her work focuses on improving breast surgery and reconstruction outcomes, and she brings both a surgeon's and a patient's perspective to care.

**CONNECT WITH DR. ANNE PELED**

Website: https://www.annepeledmd.com
Instagram: https://www.instagram.com/drannepeled/

**SPONSOR**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 Body fat, estrogen, and breast cancer risk
00:24 Ana's personal connection and the questions this episode explores
01:33 Meet Dr. Anne Peled
03:29 Early detection, family history, and breast density
05:59 Mammograms and questions about additional scans
07:33 Exercise, alcohol, and nutrition
10:05 Weight, inflammation, and emerging GLP-1 research
11:18 GLP-1s for prevention: What we still don't know
13:39 Sponsor: Tyde Wellness
15:05 GLP-1 cancer concerns and unanswered questions
16:30 Why breast cancer treatment can affect weight
18:58 Discussing GLP-1 treatment with your care team
20:12 Protecting nutrition during cancer treatment
22:53 Survivorship and personalized treatment
25:12 Emerging microbiome research
26:44 Beyond the Shot guide
27:46 Genetics and the future of personalized screening
31:03 Self-advocacy, second opinions, and everyday movement
32:46 Connect with Dr. Peled

MORE FROM GLP-1 HUB
📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub
*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.
*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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How are GLP-1 type medications and weight control changing the landscape of heart health? If you're using a GLP-1 for weight or blood sugar, which habits and risk factors still deserve attention? Ana Reisdorf talks with Dr. Melanie Icard about stress, sleep, muscle, food choices, and questions to bring to your healthcare team when heart disease runs in the family.

Dr. Icard shares how her experience with prediabetes shaped her practice and why she asks patients, "What are you doing to relax?" Ana brings the GLP-1 user's perspective: how to eat well with a smaller appetite and make strength work realistic when life is already full. They also discuss what Ana's family history has prompted her to ask about lab markers and heart imaging.

**IN THIS EPISODE**

- Why stress and sleep belong in a conversation about heart and metabolic health
- What it can look like to make room for real rest during a busy week
- How strength work and everyday movement fit into GLP-1 weight loss
- Choosing nourishing meals when your appetite is smaller
- Questions to ask your clinician about family history, lab markers, and heart imaging
- Building habits you can keep up as your health goals change

**ABOUT THE GUEST**

Dr. Melanie Icard, NMD, is a naturopathic and regenerative medicine physician with 24 years of clinical experience, including 11 years in hospital medicine. She leads Dr. Mel Holistic, a cardiovascular and metabolic medicine practice in Scottsdale and Sedona, Arizona, with a national virtual practice. Her Biohacked Heart Blueprint™ examines how chronic stress and HPA axis dysregulation (changes in the body's stress response) may relate to cardiovascular and metabolic health. She teaches the framework to medical professionals nationally.

**CONNECT WITH DR. MELANIE ICARD**

Website: https://www.drmelanieicard.com/
Instagram: https://www.instagram.com/drmelholistic/
YouTube: https://www.youtube.com/@Itsdrmel

**SPONSORS**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 What are you doing to relax?
00:18 Ana's family history and heart health beyond the scale
01:11 Meet Dr. Melanie Icard
06:23 Family history, calcium scoring, and prevention
07:09 Stress and sleep in the heart health conversation
08:44 Heart imaging and risk questions
12:58 Finding time to truly relax
15:42 Sponsor: Tyde Wellness
17:19 Stress, blood sugar, and GLP-1 goals
20:41 Meal habits and nutrient dense choices
23:54 Lab markers, imaging, and family risk
26:53 GLP-1s and preserving muscle
28:09 Making relaxation realistic
29:23 Beyond the Shot guide
30:24 Workload, boundaries, and healthy habits
32:10 Who Dr. Icard works with
33:42 Connect with Dr. Icard

MORE FROM GLP-1 HUB
📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub
*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.
*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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If you're taking a GLP-1, you've probably heard plenty about protein and strength training. Where does creatine fit, and what does it mean if the scale rises after you start taking it? Ana Reisdorf talks with Kristin Kirkpatrick about muscle health, the practical choices involved in taking creatine, and what the research can and cannot yet tell us about benefits beyond the gym.

Kristin explains how creatine works alongside resistance training, why a loading phase may not be necessary, and what to consider when choosing a form. She and Ana also discuss bloating, water retention, early research on brain health, and whether you can build muscle after starting a GLP-1.

**IN THIS EPISODE**

- What creatine does in the body and why it comes up in the muscle-health conversation
- How creatine, protein, and resistance training fit together during GLP-1 weight loss
- What emerging research suggests about brain health and what it does not establish
- Creatine monohydrate, HCl, powders, and gummies: questions to consider when choosing a product
- Loading phases, dose, and timing, and why individual needs vary
- Water retention, bloating, and why a change on the scale may not mean fat gain
- Building strength and muscle after starting a GLP-1

**ABOUT THE GUEST**

Kristin Kirkpatrick, MS, RD, is a registered dietitian at Cleveland Clinic and president of KAK Consulting, LLC. She has worked in nutrition and integrative care for more than 20 years, contributes to TODAY.com, and co-authored Skinny Liver and Regenerative Health with gastroenterologist Ibrahim Hanouneh, MD.

**CONNECT WITH KRISTIN**

Website: https://www.kristinkirkpatrick.com/
Instagram: https://www.instagram.com/fuelwellwithkrissy/

**SPONSOR**

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

Velogenix's Project Aeterna offers a free at-home mobility baseline and Pro assessments of strength, balance, and gait. Use code OFF for $50 off your first year of Pro.
https://velogenix.com

**CHAPTERS**

00:00 Why creatine is getting attention beyond the gym
01:30 Meet Kristin Kirkpatrick
03:22 Kristin's approach to integrative nutrition
06:09 What creatine does in the body
08:05 Creatine myths: Is it just for bodybuilders?
09:09 What the brain-health research can and cannot tell us
12:03 Creatine, strength training, and GLP-1 muscle health
15:13 Sponsor: Tyde Wellness
16:39 Monohydrate vs. HCl, dose, and timing
19:29 Gummies, powder, and the coffee question
23:24 Water retention, side effects, and the scale
26:07 Do you need a loading phase?
28:11 Sponsor: Velogenix
29:14 Muscle, mobility, and healthy aging
31:55 Can you build muscle after starting a GLP-1?
32:58 Connect with Kristin

MORE FROM GLP-1 HUB
📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub
*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.
*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

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What can getting out of a chair tell you about your muscle health? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins muscle and bone researcher Mark Hamrick to explore staying strong during GLP-1 weight loss, perimenopause, and menopause. You'll learn what three simple assessments can reveal about physical function, and why muscle size alone doesn't tell the whole story.

Mark explains the differences between muscle mass, quality, strength, and power, and how they connect to everyday movement and healthy aging. Ana shares her own assessment results and asks whether her regular exercise routine is enough. They also discuss bone density, fall risk, and finding an approach to exercise that works when pain or physical limitations get in the way.

**IN THIS EPISODE**

- Why losing muscle size doesn't necessarily mean losing the same amount of strength
- What chair rises, single-leg balance, and walking speed can tell you about physical function
- How menopause, sleep, and activity levels enter the muscle-health conversation
- Resistance training, protein, and the research Mark discusses on creatine
- Adapting exercise with help from a physical therapist when movement is painful
- Bone density, DEXA scans, fall risk, and questions to bring to your healthcare provider

**ABOUT THE GUEST**

Mark Hamrick is president and co-founder of Velogenix and a former Regents Professor at the Medical College of Georgia. His research on muscle and bone aging has received NIH funding over the last two decades. He has published more than 225 peer-reviewed papers and advised NASA on muscle and bone loss in space. At Velogenix, he is applying that experience to tools for quickly assessing muscle health at home.

**CONNECT WITH MARK**

Website: https://velogenix.com
LinkedIn: https://www.linkedin.com/in/mark-hamrick-44b287121/

**SPONSORS**

Velogenix, co-founded by our guest, Mark Hamrick. Project Aeterna offers at-home assessments of strength, balance, and walking speed. Try the free baseline test, or use code OFF for $50 off your first year of Pro.
https://velogenix.com

Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
https://tydewellness.com/GLP1Hub

**CHAPTERS**

00:00 Why muscle and bone health deserve attention
01:27 Meet Mark Hamrick
02:39 Three simple assessments of physical function
05:11 Muscle size, quality, and the menopause transition
09:59 The connection between muscle and longevity
12:21 Walking, strength training, and protein
13:57 Everyday signs your strength may be changing
15:08 Sponsor: Tyde Wellness
16:33 What to do with your assessment results
17:48 Exercising with pain or physical limitations
19:13 Ana's results: Is regular exercise enough?
22:22 Sitting, standing, and moving more
24:08 Bone density, DEXA scans, and fall risk
28:46 Beyond the Shot guide
29:47 Mark's three takeaways for muscle and bone health
34:19 Try Project Aeterna and connect with Mark

MORE FROM GLP-1 HUB
📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub
*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.
*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Send us Fan Mail
You've reached your goal weight on a GLP-1. Now what: stay on it, lower the dose, or take a break? Ana Reisdorf, Registered Dietitian and GLP-1 user, joins pharmacist Dr. Stephanie Redmond to explore microdosing, cycling on and off medication, and the questions coming up around perimenopause and menopause. You'll hear where clinical experience meets unanswered questions—and why a smaller dose can still bring surprises.

Stephanie shares her own experience with low-dose side effects and returning hunger. Together, they discuss concerns about weight regain and muscle loss, telehealth screening, and why your long-term plan deserves as much attention as getting started.

**IN THIS EPISODE**

- What people mean by GLP-1 "microdosing" and why the term can be confusing
- Emerging uses beyond weight loss and diabetes, and where evidence is still limited
- Stephanie's experience with constipation, bloating, and returning hunger
- Questions about cycling, stopping treatment, and maintaining weight loss
- Perimenopause, menopause, insulin resistance, and individualized care
- The role of muscle preservation, nutrition, movement, and ongoing clinical support

**ABOUT THE GUEST**

Dr. Stephanie Redmond, PharmD, CDE, BC-ADM, is a pharmacist specializing in hormone health and diabetes management. She founded the Medication Therapy Management practice at Ridgeview Clinic System in Minnesota and has educated clinicians nationally on GLP-1 therapies. She is also the founder of Dr. Stephanie's®, a clinician-led supplement brand focused on GLP-1 support, hormone health, and women's wellness.

**CONNECT WITH STEPHANIE**

Website: https://drstephanies.com
Instagram: https://www.instagram.com/drstephanies
YouTube: https://www.youtube.com/@drstephanies

**SPONSORS**

Svalto Cooler Pro is a portable, battery-powered cooler for refrigerated medication. Use code GLP1HUB for 15% off.
https://svalto.com

Velogenix's Project Aeterna offers at-home assessments of strength, balance, and mobility. Take the free baseline test, or use code OFF for $50 off your first year of Pro.
https://velogenix.com

**CHAPTERS**

00:00 GLP-1 maintenance: What happens next?
01:34 Meet Dr. Stephanie Redmond
04:08 Emerging uses and gaps in the evidence
07:46 What does "microdosing" actually mean?
11:08 Telehealth screening and questions about inflammation
14:24 Sponsor: Svalto
15:20 Weighing the risks of low-dose use
17:05 Stephanie's personal experience with side effects
18:43 Cycling, returning hunger, and weight regain
22:39 GLP-1s, perimenopause, and menopause
26:59 Sponsor: Velogenix
27:58 The future of GLP-1 use and long-term planning
32:24 Connect with Dr. Stephanie Redmond
34:19 Stay connected with GLP-1 Hub

MORE FROM GLP-1 HUB
📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
📷 Follow on Instagram: @glp1hub
📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub
*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.
*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.