🧬 The $3B Patient Recruitment Crisis: Digital Solutions | Sandra Shpilberg (Part 2/4)
“If you have an entrepreneurial spirit, what was exciting at BioMarin was that we were doing new things, innovating and creating from scratch.”
In this episode of The Biotech Startups Podcast, Sandra Shpilberg, Co-founder and COO at Adnexi, shares her journey from leading commercial launches at BioMarin to discovering the pivotal market gap in digital patient recruitment while at Nora Therapeutics—a realization that sparked her leap into founding her own company.
Her story weaves together the drive for innovation, deep patient connection, and the blend of professional ambition with personal priorities that shaped each career move.
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🧬 How Trauma Informs Purpose: Building Biotech Success | Sandra Shpilberg (Part 1/4)
"I walk around the world wanting to tell everyone that healing is possible. All types of healing are possible: physical healing, mental healing, spiritual healing. Healing is possible."
In this episode of The Biotech Startups Podcast, we explore the remarkable journey of Sandra Shpilberg, Co-founder and COO at Adnexi, from her early childhood in Uruguay to becoming a serial entrepreneur in biotech. Sandra shares the profound experiences that shaped her leadership philosophy, beginning with her family's Holocaust survivor background and her grandparents' courageous decision to start over in a new country with nothing but hope.
Sandra opens up about the defining moments that forged her resilience - from a traumatic accident at age four that sparked her lifelong belief in healing, to her family's immigration to Brooklyn when she was 16. She describes navigating American education without knowing English, watching her parents rebuild their careers, and her own journey from Wall Street to Wharton to discovering her true calling in biotech during a transformative internship at Genentech. The conversation reveals how these experiences instilled the entrepreneurial mindset and fearless approach to starting over that continues to drive her success.
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🧬 Why Drug Discovery Takes 15 Years (And How AI Cuts It to 3) | Andrey Doronichev (Part 4/4)
“If our real mission is to truly help companies get drugs to patients faster and cheaper, the amount of complexity we have to solve goes way beyond science.”
In this episode of The Biotech Startups Podcast, Jon Chee talks with Andrey Doronichev about his leap from tech at YouTube and Google to launching OPTIC and reinventing it as BIOPTIC, an AI-powered drug discovery startup.
Andrey shares the ups and downs of projects like AIorNot, the pivotal link between big data and drug development, and how “agentic AI” now drives BIOPTIC’s rapid progress—proving that real biotech breakthroughs require humility, adaptability, and big-picture thinking.
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🧬 Inside the Google vs. Apple War: Launching YouTube iOS | Andrey Doronichev (Part 3/4)
"If you as a leader of a startup—no matter how small—or you as an employee of a big organization, you could be the agent of change."
In this episode of The Biotech Startups Podcast, Andrey Doronichev traces his path from launching mobile content in Russia to transforming YouTube for mobile, overcoming fierce Google-Apple rivalry to deliver the iOS app, and pioneering VR at Google. He candidly shares lessons in resilience, startup highs and lows, and the critical role of personal influence behind major milestones, culminating in his pivot to AI-powered biotech with OPTIC.
Listeners get practical insights into team-building, dealmaking psychology, and the dynamic realities of entrepreneurship in fast-changing industries.
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🧬 How I Turned Economic Chaos Into My Biggest Advantage | Andrey Doronichev (Part 2/4)
"If you're genuinely passionate and curious about things, people will feed that curiosity. Do not underestimate that."
In this episode of The Biotech Startups Podcast, Andrey Doronichev takes us from his formative years hustling in post-Soviet Russia to launching a mobile startup amid economic chaos, emigrating as political tides shifted, and boldly landing a role at Google—all powered by grit, curiosity, and risk-taking.
Andrey reveals how bootstrapping in Russia’s early Internet boom, betting on mobile YouTube before smartphones were mainstream, and championing innovation at Google transformed both his life and the way billions interact with online video.
The Biotech Startups Podcast by Excedr features weekly conversations with founders, scientists, and investors driving biotech innovation. Host Jon Chee dives into the challenges of building biotech startups, from pre-seed to IPO. New episodes every Monday and Thursday.
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