CoinDesk Podcast Network

On this episode of CoinDesk's Public Keys from the New York Stock Exchange, host Jennifer Sanasie is joined by Strike CEO Jack Mallers, who explains why he stepped down as CEO of Twenty One Capital, makes his case for bitcoin as "the most American money," and unpacks the launch of Strike Private. Zero Knowledge Group Founder and CEO Austin Campbell breaks down the CLARITY Act's failure to advance in the Senate, why the GENIUS Act has already reshaped the regulatory landscape, and how crypto has become caught in a broader fight over congressional ethics heading into the midterms. Plus, Christian Lopez, Managing Director and Head of Blockchain and Digital Assets at Cohen & Company Capital Management, on the Fed's rate hike, how Anthropic's looming IPO is soaking up market liquidity, and why the tokenization of real-world assets is pulling Wall Street into crypto.

-

Learn more at bullish.com.

-

Register now for CoinDesk's Policy and Regulation event on September 22, 2026: policy-regulation.coindesk.com.

-

To get market-moving news delivered daily, download CoinDesk's mobile app: linktr.ee/coindeskapp.

-

Chapters/Timecodes:

00:00 Welcome to Public Keys

00:26 Markets: Bitcoin Tops $85K After the Fed Hike

00:50 Oil, Iran and the Trump-Xi Summit

01:13 Anthropic Pushes Its IPO to November

01:31 Strike CEO Jack Mallers Joins

02:04 Why Mallers Left Twenty One Capital

04:28 Mallers' Bitcoin Outlook and Advice

06:22 Why Bitcoin Doesn't Need the CLARITY Act

08:19 Bitcoin as Legal Tender and 'The Most American Money'

09:50 Inside Strike Private and Bitcoin-Backed Loans

13:10 Austin Campbell on the CLARITY Act's Senate Defeat

14:58 Why GENIUS Already Changed the Game

16:01 Crypto, the Midterms and the Ethics Fight

18:00 Could a Future Administration Undo the Rules?

19:47 Stablecoins as the Leading Force

21:35 Bitcoin and Ether ETF Flows

22:24 Christian Lopez on the Fed and Risk Assets

24:28 How the Anthropic IPO Soaks Up Liquidity

26:21 Q3 Earnings and Tokenizing Real-World Assets

28:44 Why TradFi Is Racing Into Crypto

The SEC approved its "innovation exemption" that brings stocks on-chain.

Google and Apple are both hiring for digital-asset roles, from tokenizing real-world assets in Asia to Apple Pay strategy, a sign that stablecoins and tokenization are becoming core expertise inside Big Tech. CoinDesk's Uyen Truong hosts "CoinDesk Daily."

-

This episode is brought to you by RealFi, a smarter stablecoin, backed by real-world assets. Find out more at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ realfi.co⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

-

This episode is brought to you by Grayscale, the world's largest digital asset-focused investment platform. Grayscale's mission is to make digital asset investing simple and open to every investor. Learn more at grayscale.com.

-

This episode was hosted by Uyen Truong. “CoinDesk Daily” is produced by Jennifer Sanasie and edited by Victor Chen.

The SEC approved its "innovation exemption" that brings stocks on-chain.

The SEC approved a five-year "innovation exemption" that lets firms trade real tokenized U.S. stocks on public blockchains, favoring tokens that carry full shareholder rights over synthetic price-tracking products. The move opens a regulated lane for DeFi and puts pressure on offshore offerings like Robinhood's stock tokens and Kraken's xStocks. CoinDesk's Uyen Truong hosts "CoinDesk Daily."

-

This episode is brought to you by RealFi, a smarter stablecoin, backed by real-world assets. Find out more at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ realfi.co⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

-

This episode is brought to you by Grayscale, the world's largest digital asset-focused investment platform. Grayscale's mission is to make digital asset investing simple and open to every investor. Learn more at grayscale.com.

-

This episode was hosted by Jennifer Sanasie. “CoinDesk Daily” is produced by Jennifer Sanasie and edited by Victor Chen.

Nikhil Chandhok, Chief Technology and Product Officer at Circle, joins CoinDesk Contributor Kate Irwin on Markets Outlook the day Arc mainnet goes live. Chandhok explains why gas on Arc is USDC and not a native token, how opt-in privacy works, why BlackRock and Visa signed on as validators, and what changes for institutions when GENIUS rules take effect in January.

Plus, Beezie Founder and CEO Andrea Miele on why tokenized luxury goods are the next frontier for provenance and liquidity.

-

This episode is brought to you by Grayscale, the world's largest digital asset-focused investment platform. Grayscale's mission is to make digital asset investing simple and open to every investor. Learn more at grayscale.com.

-

This episode is brought to you by RealFi, a smarter stablecoin, backed by real-world assets. Join the Testnet now at realfi.co.

-

Timecodes:

00:00 - Nikhil Chandhok Joins Markets Outlook

00:59 - CLARITY Failed. Why GENIUS Is Circle's Guiding Light

02:37 - Circle Announces Arc Mainnet

03:00 - How Opt-In Privacy Works on Arc

04:35 - Why Gas Is USDC and Not a Native Token

06:52 - Will AI Agents Take Over Onchain Activity?

10:10 - Brand New Rails: Tokenized Luxury with Beezie

13:11 - Why BlackRock and Visa Signed On as Validators

15:20 - DeFi on Arc: Aave, Morpho and Uniswap

16:43 - The Biggest Challenge Facing Institutions

18:45 - Bitcoin, Ethereum, and Why Circle Isn't Bearish

The CLARITY Act comes down to a procedural vote.

The U.S. Senate votes today on whether to advance the Clarity Act, crypto's market structure bill. A pass moves the industry closer to its first clear U.S. rules, while a failure would likely shelve the effort until after the November midterms. Bitcoin slipped to below $77,000 as Polymarket odds on the bill faded. CoinDesk's Uyen Truong hosts "CoinDesk Daily."

-

This episode is brought to you by RealFi, a smarter stablecoin, backed by real-world assets. Find out more at⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ realfi.co⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

-

This episode is brought to you by Grayscale, the world's largest digital asset-focused investment platform. Grayscale's mission is to make digital asset investing simple and open to every investor. Learn more at grayscale.com.

-

This episode was hosted by Jennifer Sanasie. “CoinDesk Daily” is produced by Jennifer Sanasie and edited by Victor Chen.