PodcastsBusinessWhat's Your Problem?

What's Your Problem?

iHeartPodcasts and Pushkin Industries
What's Your Problem?
Latest episode

185 episodes

  • What's Your Problem?

    Mass-Producing Stem Cells to Cure Disease

    2026/1/15 | 34 mins.

    Nabiha Saklayen is the co-founder and CEO of Cellino. Nabiha’s problem is this: How can you make personalized stem cell therapies quickly and cheaply? Induced pluripotent stem cells, or IPSCs, have shown tremendous promise as treatments for illnesses like Parkinson’s, leukemia, and heart disease. On today’s show, Nabiha explains why IPSC manufacturing is still mostly done by hand, how her background in physics and lasers led her into biology, and what it takes to try and build tiny, automated cell factories.See omnystudio.com/listener for privacy information.

  • What's Your Problem?

    From Kill Switch: The Glassholes Are Back

    2025/12/25 | 39 mins.

    Today, we're sharing an episode of a show that explores the problems that new technology is creating and how we navigate living in the future. It's called Kill Switch, and it's hosted by Pulitzer Prize-winning journalist, Dexter Thomas. The episode you're about to hear is about the latest in wearable tech—stuff like smart glasses, pendants, watches and rings. After the implosion of Google Glass back in 2013, which faced backlash and ridicule, we’re now readily embracing wearables. What’s behind the new fervor of wearables today, and have we moved on from the privacy and surveillance questions that plagued Google Glass? Dexter talks to Victoria Song, a senior reviewer at The Verge whose job it is to test out each new iteration of this technology, about the state of wearables today, why companies are obsessed with getting AI into them, and how they’ve already changed how we talk to each other, and ourselves, IRL. Find more episodes of Kill Switch wherever you get podcasts. Got something you’re curious about? Hit them up [email protected], or @killswitchpod, or @dexdigi on IG or Bluesky.See omnystudio.com/listener for privacy information.

  • What's Your Problem?

    Building a Self-Driving Tractor to Change the Future of Food

    2025/12/18 | 43 mins.

    Please take our survey https://tinyurl.com/wyplistenersurvey about the show! Tell us what you want to hear, and what would make it better. Tim Bucher is a farmer, and the founder and CEO of Agtonomy. Tim's problem is this: How do you build an autonomous tractor that can work for specialty crops like grapes, olives, apples, and almonds? On today’s show, Tim explains what makes certain farming processes so difficult to automate, and how autonomy may soon change how we eat.See omnystudio.com/listener for privacy information.

  • What's Your Problem?

    We’re Going to Need a Better Boat

    2025/12/11 | 35 mins.

    Mitch Lee is the co-founder and CEO of Arc Boats. Mitch's problem is this: How do you build competitively priced electric boats?On today’s show, Mitch explains why water makes electrification so hard, the techno-economic puzzle of building giant battery packs, and how Arc’s high-end wake sport boat opened the door for a new generation of hybrid-electric tugboats.See omnystudio.com/listener for privacy information.

  • What's Your Problem?

    How to Experience the Joy of Giving Right Now: A Giving Tuesday Special from The Happiness Lab

    2025/12/02 | 47 mins.

    According to the science, it really is better to give than receive. Donating a dollar; sharing a kind word or lending someone a hand changes lives, but can also hugely boost your happiness. So we're teaming up with other podcasts from Hidden Brain to Revisionist History to ask you to give to a charity helping some of the poorest people around. We're calling it #PodsFightPoverty. Go to givedirectly.org/happinesslab right now and give whatever you can. And the first $500,000 we donate will be matched thanks to our friends at Giving Multiplier! Even a small donation will make you feel good and have a much larger impact on the world than you thought possible. To help inspire you, this special episode examines the science of giving and shares stories of heartwarming and impactful acts of kindness. See omnystudio.com/listener for privacy information.

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About What's Your Problem?

Every week on What's Your Problem?, former Planet Money host Jacob Goldstein talks with entrepreneurs and engineers tackling the biggest challenges at the forefront of technology. How do you make a trip to space as routine as a plane flight? How do you turn solar energy into clean fuel? How do you use AI to stop deadly infections before they spread? We hear a lot these days about how the world is getting worse. What's Your Problem? learns from the thinkers and doers trying to make our future better. iHeartMedia is the exclusive podcast partner of Pushkin Industries.
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