Science Friday

On February 12, the Environmental Protection Agency dealt a major blow to the government’s power to fight climate change by rescinding a key piece of research called the endangerment finding. The finding, issued in 2009, basically says: Greenhouse gas emissions endanger public health and welfare—and because they’re harmful, they must be regulated. It's the legal basis for the federal government’s regulation of greenhouse gases under the Clean Air Act. So what does it mean that this finding has been thrown out?

Host Flora Lichtman digs into this question with Andy Miller, an original author on the endangerment finding who spent more than 30 years working for the EPA.

Guest:

Dr. Andy Miller worked on air pollution and climate change at the EPA for more than 30 years. He was an original author on Endangerment Finding.

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An estimated 500,000 people are diagnosed with Alzheimer’s disease in the United States each year, but the causes and mechanisms of the condition remain a neurological mystery. A recent study looked at the role of variants in a gene called APOE in Alzheimer’s, and found that while it’s not a simple determinant of developing the disease, that one gene seems to play a significant role in promoting disease risk. Researchers hope work like this could point to new areas to study and even potential treatments.

Epidemiologist Dylan Williams joins Host Ira Flatow to explain the findings and discuss the challenges in tracing a complex disease to its roots.

Guest: Dr. Dylan Williams is a principal research fellow in molecular and genetic epidemiology at University College London.

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Does the availability of “hemp-derived” THC products have you dazed and confused? A legal loophole in the 2018 Farm Bill lets these items be sold over the counter. But state actions, and a federal law that could come in November, aims to snuff these products out. 

Host Flora Lichtman talks to cannabis expert Cinnamon Bidwell about the confusing legal landscape, and the real differences between products. Plus, investigative reporter Joe Hong talks to Flora to break down his findings of what’s lurking in NYC’s dirty snowbanks.

Guest:

Dr. Cinnamon Bidwell is a clinical psychologist focused on cannabis at the University of Colorado. She co-directs the CU Change lab.

Transcripts for each episode are available within 1-3 days at sciencefriday.com.

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Despite major advances in our understanding of the biology of mental health disorders,  there’s no blood test or brain scan that will confirm if you have depression, anxiety, PTSD, or any other psychiatric illness. 

And yet, the American Psychiatric Association recently announced that it will be including biomarkers for mental conditions in the next edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM), which guides diagnosis and treatment of mental illness. So how close are we to pinpointing the biological markers of mental illness, and what does that mean for diagnosis? It’s complicated. 

Host Flora Lichtman untangles some of this science with psychiatry researcher John Krystal.

Guest: Dr. John Krystal is a professor of psychiatry, neuroscience, and psychology at the Yale School of Medicine.

Transcripts for each episode are available within 1-3 days at sciencefriday.com.

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There’s a long-held idea that autism is more prevalent in boys than girls—the CDC says it’s three times as common. But a growing body of research suggests the reality is more complicated. In a new study, researchers tracked autism diagnoses in millions of Swedish people born from 1985 to 2022. They found that the prevalence of autism is actually pretty even across the sexes, but people with “female” stamped on their birth certificate are often diagnosed later in life. 

Host Flora Lichtman speaks with epidemiologist Caroline Fyfe about what this study teaches us about the prevalence of autism. Then, psychology researcher Rachel Moseley, an autistic woman herself, shares how late and missed diagnoses can affect autistic people.

Guests:

Dr. Caroline Fyfe is an epidemiologist at the University of Edinburgh who studied sex differences in autism diagnoses. 

Dr. Rachel Moseley is a researcher in psychology at Bournemouth University in the UK, studying the experiences of autistic adults.

Transcripts for each episode are available within 1-3 days at sciencefriday.com.

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