Plain English with Derek Thompson

Donald Trump’s polling has continued to edge down week after week. And yet approval of the Democratic Party is still stuck near its all-time low, according to Gallup and other surveys.

One interpretation of these polls is that the deep unpopularity of the party is an albatross around the neck of Democratic candidates. But there’s another interpretation that I think is more interesting—and perhaps more true. The fact that the party has no clearly defined national leader, and no clearly defined “brand” (sorry), is an opportunity for young Democrats to define themselves as individuals. Rather than act like a congregation all singing from the same hymnal, they can experiment, disagree, and adapt their message to their electorate. And that might ultimately prove to be a strength of the party heading into the 2026 midterms rather than a weakness.

Senator Ruben Gallego (D-Arizona) joins the show to talk about the Iran war, immigration, affordability vs. aspiration, and the future of the Democratic Party.

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If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek ThompsonGuest: Ruben GallegoProducer: Devon Baroldi
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Dramatic regime change. Moderate regime evolution. A calamitous regional conflict. Or … no change at all. Today we consider how the Iran conflict might evolve following the killing of Supreme Leader Khamenei with Karim Sadjadpour, an American policy analyst at the Carnegie Endowment for International Peace.

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If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek ThompsonGuest: Karim SadjadpourProducer: Devon Baroldi
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The modern world swims in numbers: work metrics, fitness metrics, health metrics, social media metrics. Sometimes the quantification of life can make things better. But very often, I think they force us to play the games we can measure rather than the games we value. The quantified life has become a modern religion: a system of values that takes us over and keeps us from living the life we want.

Today’s guest is the philosopher C. Thi Nguyen. He is the author of the book The Score: How to Stop Playing Somebody Else's Game. We talk about metrics, the games of life, and how to listen to the parts of ourselves that cannot be reduced to numbers.

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If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek Thompson

Guest: C. Thi Nguyen

Producer: Devon Baroldi
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The GLP-1 drug revolution has taken the medicine world by storm. I’ve done several episodes on the science of GLP-1s. But we’ve never done an episode like this before, where we talk to one of the most important people in charge of guiding the GLP-1 drug revolution.

Our guest is Dave Ricks, the CEO of Eli Lilly, the largest pharmaceutical company in the world. First we talk about what makes the GLP-1 drug category special and the science that Lilly is doing to improve these drugs. Then, we talk about the pharmaceutical industry more broadly. How it works. How it could work better. And I don’t shy away from the question that I think Pharma CEOs need to take much more seriously: If the pharmaceutical industry is theoretically more devoted than any other economic category to saving people’s lives, why do Americans distrust it more than any other industry in the entire economy?

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek ThompsonGuest: David RicksProducer: Devon Baroldi
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Donald Trump suffered a huge blow Friday when the Supreme Court struck down the centerpiece of his economic policy: his vast system of tariffs. So, what happens now? Harvard’s Jason Furman explains the implications for the U.S. economy, consumers, global trade, and Trump’s strategy of centralizing power in the executive branch and using trade policy as a means of wringing concessions out of other counties.

Subscribe to our YouTube channel here: https://www.youtube.com/@PlainEnglishwithDerekThompson

If you have questions, observations, or ideas for future episodes, email us at [email protected].

Host: Derek ThompsonGuest: Jason FurmanProducer: Devon Baroldi
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