JHLT: The Podcast

JHLT: The Podcast continues its exploration of recent consensus documents this month by discussing "Assessing and Addressing Frailty in Candidates for Lung Transplantation: An ISHLT Consensus Statement."
The statement appears online now at JHLT, and a helpful companion perspective piece from the authors can be read in your October print issue of the Journal.
Today's guests are project leads Michaela Anderson, MD, MS, of the Hospital of the University of Pennsylvania, and Jonathan Singer, MD, MS, of the University of California San Francisco.
In their discussion, they cover:
What real-world teams want to know about frailty and how their document enhances clinical capacity
How programs decide which tools to use to use to measure frailty—and which are most relevant to lung transplantation
The importance of—and best timing for—universal assessment
What's next in studying frailty
Stay up to date with official standards and guidelines documents from ISHLT at ISHLT.org. For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Today, JHLT: The Podcast discusses the recent ISHLT consensus document "Baseline Lung Allograft Dysfunction: Definition, Timing, and Implications for Outcomes—An ISHLT Consensus Document."
Now available online at JHLT—and a helpful companion perspective piece from the authors appears in the print October issue of JHLT.
Today's guests are co-leads on the document, Jens Gottlieb, MD, of Hannover Medical School and Kieran Halloran, MD, MSc, of the University of Alberta.
They discuss:
Why rapid increases in usage of "BLAD" in the literature meant it was time for a formal definition
Major considerations and areas of debate during the writing process
How clinicians should think about patients meeting the criteria for BLAD and how the evaluation of underlying etiologies took place
Interpreting BLAD's potential relationship to CLAD
Stay up to date with official standards and guidelines documents from ISHLT at ISHLT.org. For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

In this episode, JHLT: The Podcast continues the Pulmonary Hypertension theme for the month, exploring the study "Long-Term outcomes of stent-based pulmonary angioplasty for isolated peripheral pulmonary artery stenosis," which appears in the September print issue of JHLT.
Today's guest is author Hiroto Shimokawahara, MD, of the Okayama Medical Center in Japan.
Dr. Shimokawahara's discussion with Digital Media Editor Van-Khue Ton covers:
What the study contributes to the clinical literature with longer-term outcomes of stent-based pulmonary angioplasty in peripheral pulmonary artery stenosis (PPAS)
How the diffuse nature of PPAS and the advanced stage of disease complicates treatment options
The evolution of stent choices and technologies in the last 20 years of clinical practice at their center
Ideal follow-up conditions for monitoring patients after PPAS stenting
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

Today, JHLT: The Podcast discusses "Long-term effects of medical therapy pre- and post-pulmonary endarterectomy—insights from the UK CURATE registry," a manuscript available online now and in the September print issue of JHLT.
Today's guest is first author Paula Appenzeller, MD, of the National Pulmonary Vascular Diseases Unit at Royal Papworth Hospital in Cambridge.
In the episode, Dr. Appenzeller and the editors discuss:
How findings from the UK CURATE registry challenge assumptions about pre-operative therapy in CTEPH
What's important about the 6-minute walk distance test
How hemodynamics help guide post-PEA treatment decisions
If multimodal CTEPH treatment could become the norm
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.

In this episode, JHLT: The Podcast explores the study "The ASSIST CLAD study: A phase 2 randomized controlled trial of mesenchymal stromal cells for new-onset chronic lung allograft dysfunction," which appears in the August print issue of JHLT.
Today's guest is Daniel C. Chambers, MBBS, MD, of The Prince Charles Hospital and Queensland Lung Transplant Service in Brisbane, Australia.
From across the dateline, he and Digital Media Editor Erika Lease discuss:
What inspired the team to explore the use of mesenchymal stromal cell (MSC) infusions in CLAD patients
Preparation and treatment considerations for using MSCs
How despite the negative outcome—the MSCs made no clear improvements in the patient groups—the study still pushes the field forward
For the latest studies from JHLT, visit www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.
Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.