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4-Quarter Lives

Avivah Wittenberg-Cox
4-Quarter Lives
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  • Implementing the Longevity Future - Where the Rubber Hits the Demographic Road
    Welcome to 4-Quarter Lives, a podcast exploring the profound impact of longer, healthier and more engaged lives, not only for ourselves and our couples, but also for companies and countries. I’m Avivah Wittenberg-Cox, and today, I’m doing a summary of our 9th season of this podcast.Each season of 4-Quarter Lives feels like a tapestry—woven from voices, visions, and lived experiments in the age of longevity. Season 9 may be the most practical yet: full of builders, architects, and reimagineers of how we live, age, and contribute across life’s 4 Quarters.Instead of summarising episode by episode, I’ve stepped back to distil the bigger picture. Across ten cool conversations, three conclusions emerged that I believe are shaping the future we need—urgently, optimistically, and globally.Longevity is Inspiring a New Generation of Products & ServicesOne of the clearest patterns to emerge this season was the burst of creativity in the longevity economy—services that meet both the challenges and possibilities of longer lives.There’s a beautiful throughline here: that midlife and later life are not just about winding down, but winding differently. These new services are creating options for housing, purpose, income, and legacy—often in deeply intergenerational ways.* Lisa Goldsobel’s work at Two Generations was a standout. Matching older homeowners with younger renters is more than a housing fix—it’s a loneliness solution, a purpose-provider, and an empathy engine.* Laurie Kilby reminded us that fostering isn’t just for the young. An innovative new platform, Now Foster, inspired by Now Teach founder Katie Waldegrave, taps into the experience and spaciousness of midlife to invite people to support children in care—through flexible roles that are redefining what caregiving can look like - one weekend a month.* Farah Baxter and Ignacio Moreno reframe legacy as something emotional and accessible. Their platform, Soalma, helps people record and share their stories, values, and advice (as well as admin details and paperwork)—a kind of “emotional will” that may turn out to be more lasting than any financial or legal one.* Julianne Miles runs Career Returners, and her new book Return Journey shares the lessons of thousands of people who’ve gone back to work after an extended break. As lives and careers lengthen, we’ll need more breaks, more returns and a better understanding of how to manage it all. For both individuals and companies. Here, she shares her summary view.* Neeraj Sagar’s WisdomCircle is a professional headhunter’s mature passion project. It connects retirees with companies and causes that value their insights. It’s a quiet revolution in how we value age, experience, and time. A placement platform that values wisdom and experience, not screens it out with AI. And supported by some of the top people in the business.These aren’t fringe ideas—they’re scalable, smart, and deeply human. And they share a philosophy I deeply believe in: that connection is the gift - and essential survival skill - of longevity.Conclusion: Intergenerational design isn’t just nice—it’s necessary. Longevity done well serves - and benefits - all ages.It’s Not Just Lifespan. It’s Also Healthspan—and Fullspan.This season deepened my conviction that living longer isn’t the point, despite billions being invested to do just that. The goal is simpler and a lot cheaper. Live better, longer. And to do that, we need new definitions, new metrics, and new mindsets.Three guests stood out in shaping this thinking:* Richard Leider, a global pioneer in ‘purpose’ coaching, reminded us that meaning is a biological imperative. Purpose doesn’t just extend our years—it enriches them. And it’s most powerful when it’s practical, everyday, and shared. And it doesn’t have to have a capital ‘P.’* Melinda Blau, with her signature blend of warmth and research, reframed ageing as a relational journey. It’s not about the family you’re born into, but the “wisdom friends” you cultivate. She shares her latest book, The Wisdom Whisperers, showcasing her deep friendships with nine ‘old ladies’ who taught her how to age.* Mileham Hayes brought the physician’s lens—one sharpened by decades in cardiac care. His message was sobering but hopeful: most of the major killers in older age are preventable. But only if we start testing and treating risk early and personally. So he shares what is most likely to kill you in every decade and what tests you should run to prevent that happening to you.Together, they drew a new kind of longevity triangle: Purpose. Prevention. People. The three “Ps” of fullspan health.Conclusion: We must stop treating ageing as a condition to be endured and start designing for energy, connection, and meaning at every stage.To Matter, Longevity Must Be Local—and GlobalThe final message of the season took us beyond the West—and into the rich, diverse realities of aging in the Global South. We often talk about longevity as if it’s only happening in wealthy countries. But the data says otherwise—and so do our guests.* Saher Mehdi, a molecular biologist turned health entrepreneur in India, is creating AI-guided diagnostics specifically for women. Her work on biological age is brilliant—but her motivation is even more striking. She’s filling a gap that most Western systems barely acknowledge: affordable, gender-informed longevity care in low-resource settings.* Maria Clara Pinheiro, who leads Ashoka’s longevity work in India, showed how older adults are being empowered not through government policy, but social innovation. She highlighted grassroots leaders—from grandmother-led mental health programmes in Zimbabwe to intergenerational educators in Brazil—who are reframing age as an asset.Their work reminded me that ageing may be universal, but the solutions must be rooted in culture, context, and equity. Longevity is not just a science—it’s a social contract.Conclusion: The future of aging is not one-size-fits-all. It’s local, lived, and deeply varied. Listening is the first act of innovation.Where Do We Go From Here?Looking back on Season 9, what struck me most was how tangible it all felt. These weren’t just ideas. They were already becoming reality. Quietly, bravely, and beautifully.If Season 8 explored the demographic disruption, Season 9 revealed the builders. People crafting new scaffolding for longer lives: services, tools, mindsets, and movements that meet the realities of Q3 and Q4 with grace and ambition.So what are we left with?* A reframing of ageing as something profoundly creative.* A call to think beyond “lifespan” toward “fullspan.”* And a reminder that if we design this right, longevity could be not just an extension—but an expansion.What are you building for your next quarter?We’ll be back in the fall with Season 10. I’ll be featuring the Directors of many of the world’s leading midlife transition programmes in top universities - from Harvard’s ALI, Stanford’s DCI to Oxford and Cambridge’s more recent additions. If ever you’re tempted by some later life educational breaks, this one will be for you.Until then—stay curious, stay connected, and keep designing a life, and a Quarter, that fits who you are becoming.You can find Season 9 on a phone near you, on any podcast platform, or right here on Substack. Get full access to Elderberries at elderberries.substack.com/subscribe
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  • Julianne Miles: The Power of Career Breaks
    This week on 4-Quarter Lives, Avivah Wittenberg-Cox welcomes Julianne Miles, career psychologist and co-founder of Career Returners, to discuss her forthcoming book Return Journey: How to get back to work and thrive after a career break. A leading voice in the returner space, Julianne has spent over a decade supporting thousands of professionals - many in midlife - relaunch their careers after extended breaks.In this conversation, Julianne reveals her own return-to-work story and why writing Return Journey was both personal and timely. She outlines the book’s three-stage structure - from initial mindset shifts, to finding ‘work that works’, to thriving once back at work - and explains why internal blockers like guilt and perfectionism can be just as limiting as external biases and ageism in the workplace.We explore what makes Q3 returners unique in this ‘return journey’, the myths around age and ability, and why employers should view returners not as charity hires but as motivated, experienced talent. Julianne also offers practical exercises, the value of ‘realistic optimism,’ and why intuition may be your most overlooked superpower.Whether you’re returning, hiring, or simply curious about the future of work trends, this episode - and Julianne’s book - offers a roadmap to getting ready for navigating the ins and outs of our new, 60-year careers.Return Journey is out in September 2025.Julianne Miles MBE is a chartered occupational psychologist, INSEAD MBA graduate, and, since 2014, cofounder, CEO and now Executive Chair of Career Returners (formerly Women Returners). After an early career in strategy consulting, and marketing at Diageo in the UK and Australia, she took a fouryear break to raise her children before obtaining an MSc in Organisational Psychology. Identifying the “career break penalty,” she launched Career Returners to build returntowork programs (“returnships”) and a peer network community, partnering with over 200 organisations and supporting over 3,500 professionals. With 10,000 network members, this social impact business reshapes hiring norms. In 2019 Julianne was awarded an MBE for services to business and equality.USEFUL LINKS* Buy Return Journey: How to get back to work and thrive after a career break, (To be published on 4 Sept 2025)* Visit Career Returners website* Join the Career Returners Community* Listen to the Career Returners Podcast Get full access to Elderberries at elderberries.substack.com/subscribe
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  • Maria Clara Pinheiro: Social Entrepreneurship as a Lifelong Contribution
    In this week’s 4-Quarter Lives, Avivah Wittenberg-Cox talks with Maria Clara Pinheiro, Co-lead of Ashoka’s New Longevity Initiative. Ashoka, the world’s largest network of social entrepreneurs, has identified longevity as a key emerging trend through a bottom-up approach, observing a growing number of its fellows tackling issues related to ageing populations. This led to a global mapping of 100 fellows’ work and the launch of Ashoka’s “New Longevity” initiative. Five key themes emerged: changing the narrative around ageing, lifelong learning and work, health and care, intergenerational relationships, and economic security and inclusion.Maria Clara emphasizes the unifying concept of “lifelong contribution,” where every individual, regardless of age, is seen as a potential changemaker. She shares powerful examples, including Dixon Chibanda’s Friendship Bench project in Zimbabwe, where grandmothers are trained to provide mental health support.The conversation also explores cultural and regional differences, noting how countries like Brazil, India, and Indonesia are aging rapidly without the same infrastructure as the West. To respond, Ashoka is launching localized “Longevity Labs” to drive systems change and foster collaboration among entrepreneurs, universities, companies, and governments. India, despite its youthful reputation, is revealed to have over 150 million older adults—a powerful yet underrecognized force in shaping the country’s future. Maria Clara paints a compelling picture of how countries like India, Brazil and Zimbabwe are incubating the next wave of ageing innovation – community-driven, tech-enabled, and radically inclusive.Ashoka is a nonprofit organization that promotes social entrepreneurship by connecting and supporting individual social entrepreneurs. It invests in over 4,000 social entrepreneurs in over 90 countries worldwide. The aim is that these individuals in turn become the people that others will try to follow by example.Maria Clara Pinheiro co-leads Ashoka’s Global New Longevity initiative. She joined Ashoka in 2003 and has held leadership roles in Brazil, The United States and India. Over that time she has supported social innovators, built entrepreneurial teams and led a range of global programmes and partnerships for Ashoka. Useful Links:* Ashoka’s New Longevity Initiative website* Ashoka website* Friendship Bench website Get full access to Elderberries at elderberries.substack.com/subscribe
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  • Mileham Hayes: A Q4 Doctor on Longer Lives – Avoiding the Big Killers
    This week, on 4-Quarter Lives, Avivah Wittenberg-Cox talks with Dr Mileham Hayes, author of ‘Live Longer: Revealing Today’s Secrets of Longevity and Wellbeing’ and a specialist in preventative medicine. As he says, "preventive medicine has never realized its promise or potential...until now". Mileham, who launched the world’s first longevity clinic and has spent nearly six decades in coronary care, shares how much of heart disease—still the world’s top killer - is preventable, yet persistently neglected. He discusses key diagnostic tests such as ApoB, Lp(a), and coronary artery calcium scans, many of which he began using in the 1990s but still remain underused. He advocates a targeted 20-test health screening battery for anyone over 40, customized by age and gender, which is downloadable with the episode.He critiques the broader health ecosystem where profit-driven industries—from pharma to fast food—drown out preventive efforts, leaving doctors and patients with minimal influence. He shares sobering statistics on the top causes of death by decade and gender across the US, UK, and Australia—highlighting suicide as a leading killer of younger men. Rather than obsessing over radical life-extension strategies, Hayes urges a back-to-basics focus on preventing known, measurable threats. Witty, forthright, and deeply experienced, Hayes is a passionate advocate for practical, accessible healthcare that prioritizes staying alive—and healthy—as the first rule of longevity.Dr Mileham Hayes is a Specialist Physician and a Fellow of both the Royal College of Physicians of London and Edinburgh. He was appointed to the world's first Coronary Care Unit and researched prevention of heart attacks – still the greatest cause of premature death. He has now spent some 50 years in clinical practice and is the author of two medical textbooks and a series of books on living longer through prevention, nutrition and exercise. His most recent book is ‘Live Longer: Revealing Today’s Secrets of Longevity and Wellbeing’. Mileham studied medicine at the University of Queensland. He has five children, played most sports at a high level, farmed, gardens, writes doggerel and cooks. He also had an ABC radio weekly program and two national TV shows presenting and playing jazz. He has the Order of Australia Medal for his services to Jazz.Useful Links:* Download a pdf by Mileham of a list of actions to Live Longer* Buy Mileham’s book ‘Live Longer’* On Amazon.com* On Amazon.co.uk Get full access to Elderberries at elderberries.substack.com/subscribe
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  • Saher Mehdi: Ageing & Gender at a Cellular Level
    In this week’s 4-Quarter Lives, Avivah Wittenberg-Cox is joined by Dr. Saher Mehdi- molecular biologist, longevity researcher, and healthcare entrepreneur, to explore what it truly means to age well.Saher traces her journey “from molecules to meaning,” beginning with a childhood curiosity sparked by her grandmother’s ageing hands. That moment led to a lifelong inquiry into the biology of ageing, one that took her across continents and disciplines. With a PhD from Durham University and postdoctoral research at Oxford, Uppsala, and KU Leuven, her research has spanned cell fate, cardiac regeneration, epigenetics, and the stress responses that shape how, and how fast, we age.But her understanding of ageing evolved beyond the lab. Living and working in the UK, Sweden, and Belgium deepened her appreciation for how biology is shaped by culture, climate, and inequality. Returning to India, she saw the urgent need to translate cutting-edge science into accessible, personalised tools, especially in a country where 1 in 6 people will be over 60 by 2050, and where rising rates of diabetes and heart disease reveal a unique intersection of genetic vulnerability and environmental risk.Through her company ReWise Health, Saher is building a new approach to ageing — using AI and biomarker data to assess biological age, personalise interventions, and prevent disease before it strikes.She makes the case that ageing itself, not just chronic diseases, is the leading driver of mortality, and that slowing cellular ageing could add more healthy years to life than curing cancer or heart disease. In a striking metaphor, she compares female mitochondria to fuel-efficient hybrid engines, while male mitochondria resemble high-performance machines that burn through energy faster, illustrating the cellular gender gap in ageing.Saher continues to unpack the science of gendered ageing through telomeres, the protective caps at the ends of chromosomes that erode with time and stress. Women, she notes, tend to have longer telomeres and slower attrition, thanks to estrogen and the second X chromosome. But she also critiques the deep male bias in medical research: for decades, women, particularly post-50, have been excluded from clinical trials, creating massive knowledge gaps in care.She calls for a shift in longevity science, away from elite biohacking and toward public health equity, especially for ageing women in low-resource settings. Through ReWise, she’s designing a culturally relevant, scalable model for biological age testing and intervention, one rooted in empathy, science, and real-world impact.Dr. Saher Mehdi is a molecular biologist, epigenetics expert, and two-time founder in the field of preventive health and longevity. She founded Wellowise and now leads ReWise Health, a cutting-edge biotech building tools to personalise ageing and extend healthspan. With a PhD from Durham and postdoctoral research at Oxford, Uppsala, and Leuven, her work spans cell fate, cardiac regeneration, cellular stress, and the biology of ageing. A global voice in the science of longevity, Dr. Mehdi is redefining how we understand, measure, and optimise the experience of growing older with data, compassion, and vision.Useful Links:* ReWise Health website* Saher Mehdi’s Substack blog* Saher’s X account* Saher Linkedin Get full access to Elderberries at elderberries.substack.com/subscribe
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About 4-Quarter Lives

You are likely to live longer than you think. Are you ready? Science has gifted us ever longer, 100-year lives. This impacts… everything! From couples and careers - to companies and countries. We’ll interview the experts who are exploring the consequences – and the individuals applying it to their own lives and choices. Generational and gender expert Avivah Wittenberg-Cox talks with people designing new ways of living, working and loving at all ages – across life’s 4 quarters. elderberries.substack.com
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